• 8325 Citations
  • 47 h-Index
1980 …2019
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  • 8 Similar Profiles
Mutation Medicine & Life Sciences
Single Nucleotide Polymorphism Medicine & Life Sciences
Genes Medicine & Life Sciences
Jews Medicine & Life Sciences
Prostatic Neoplasms Medicine & Life Sciences
Population Medicine & Life Sciences
Genome-Wide Association Study Medicine & Life Sciences
Genome Medicine & Life Sciences

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Grants 1990 2019

Robust Predictor of Colon Cancer Risk

Ostrer, H.

National Institutes of Health

9/13/188/31/19

Project: Research projectSmall Business Technology Transfer (STTR) Grants - Phase I

Colonic Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms
Mutation
DNA Mismatch Repair
Bile Duct Neoplasms

Robust Predictor of Breast Cancer Risk

Ostrer, H.

National Institutes of Health

9/20/178/31/19

Project: Research projectSmall Business Technology Transfer (STTR) Grants - Phase I

Breast Neoplasms
Mutation
Germ-Line Mutation
Genetic Testing
Genes

Genomics and Predictive Modeling of Prostate Cancer Heath Disparity

Ostrer, H.

National Institutes of Health

9/16/1112/31/16

Project: Research projectResearch Project--Cooperative Agreements

Genomics
Prostatic Neoplasms
Genome
African Americans
Neoplasms

Genome-Wide Study to Identify SNPs and CNPs Associated with Radiation Injury

Rosenstein, B. & Ostrer, H.

National Institutes of Health

8/1/095/31/14

Project: Research projectResearch Project

DNA Copy Number Variations
Radiation Injuries
Single Nucleotide Polymorphism
Genome
Proctitis

MENTORSHIP PROGRAM IN PROSTATE CANCER GENETICS

Ostrer, H.

National Institutes of Health

3/14/012/28/07

Project: Research projectMidcareer Investigator Award in Patient-Oriented Research

Genetic Research
Mentors
Prostatic Neoplasms
Medicine
Translational Medical Research

Publications 1980 2018

10 Citations

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

Schumacher, F. R., Al Olama, A. A., Berndt, S. I., Benlloch, S., Ahmed, M., Saunders, E. J., Dadaev, T., Leongamornlert, D., Anokian, E., Cieza-Borrella, C., Goh, C., Brook, M. N., Sheng, X., Fachal, L., Dennis, J., Tyrer, J., Muir, K., Lophatananon, A., Stevens, V. L., Gapstur, S. M. & 167 othersCarter, B. D., Tangen, C. M., Goodman, P. J., Thompson, I. M., Batra, J., Chambers, S., Moya, L., Clements, J., Horvath, L., Tilley, W., Risbridger, G. P., Gronberg, H., Aly, M., Nordström, T., Pharoah, P., Pashayan, N., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Albanes, D., Weinstein, S., Wolk, A., Håkansson, N., West, C. M. L., Dunning, A. M., Burnet, N., Mucci, L. A., Giovannucci, E., Andriole, G. L., Cussenot, O., Cancel-Tassin, G., Koutros, S., Beane Freeman, L. E., Sorensen, K. D., Orntoft, T. F., Borre, M., Maehle, L., Grindedal, E. M., Neal, D. E., Donovan, J. L., Hamdy, F. C., Martin, R. M., Travis, R. C., Key, T. J., Hamilton, R. J., Fleshner, N. E., Finelli, A., Ingles, S. A., Stern, M. C., Rosenstein, B. S., Kerns, S. L., Ostrer, H., Lu, Y. J., Zhang, H. W., Feng, N., Mao, X., Guo, X., Wang, G., Sun, Z., Giles, G. G., Southey, M. C., MacInnis, R. J., Fitzgerald, L. M., Kibel, A. S., Drake, B. F., Vega, A., Gómez-Caamaño, A., Szulkin, R., Eklund, M., Kogevinas, M., Llorca, J., Castaño-Vinyals, G., Penney, K. L., Stampfer, M., Park, J. Y., Sellers, T. A., Lin, H. Y., Stanford, J. L., Cybulski, C., Wokolorczyk, D., Lubinski, J., Ostrander, E. A., Geybels, M. S., Nordestgaard, B. G., Nielsen, S. F., Weischer, M., Bisbjerg, R., Røder, M. A., Iversen, P., Brenner, H., Cuk, K., Holleczek, B., Maier, C., Luedeke, M., Schnoeller, T., Kim, J., Logothetis, C. J., John, E. M., Teixeira, M. R., Paulo, P., Cardoso, M., Neuhausen, S. L., Steele, L., Ding, Y. C., De Ruyck, K., De Meerleer, G., Ost, P., Razack, A., Lim, J., Teo, S. H., Lin, D. W., Newcomb, L. F., Lessel, D., Gamulin, M., Kulis, T., Kaneva, R., Usmani, N., Singhal, S., Slavov, C., Mitev, V., Parliament, M., Claessens, F., Joniau, S., Van Den Broeck, T., Larkin, S., Townsend, P. A., Aukim-Hastie, C., Dominguez, M. G., Castelao, J. E., Martinez, M. E., Roobol, M. J., Jenster, G., Van Schaik, R. H. N., Menegaux, F., Truong, T., Koudou, Y. A., Xu, J., Khaw, K. T., Cannon-Albright, L., Pandha, H., Michael, A., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Lindstrom, S., Turman, C., Ma, J., Hunter, D. J., Riboli, E., Siddiq, A., Canzian, F., Kolonel, L. N., Le Marchand, L., Hoover, R. N., Machiela, M. J., Cui, Z., Kraft, P., Amos, C. I., Conti, D. V., Easton, D. F., Wiklund, F., Chanock, S. J., Henderson, B. E., Kote-Jarai, Z., Haiman, C. A. & Eeles, R. A., Jul 1 2018, In : Nature Genetics. 50, 7, p. 928-936 9 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Confidence Intervals
Genome-Wide Association Study
Genotype
Population
1 Citations

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

Dadaev, T., Saunders, E. J., Newcombe, P. J., Anokian, E., Leongamornlert, D. A., Brook, M. N., Cieza-Borrella, C., Mijuskovic, M., Wakerell, S., Olama, A. A. A., Schumacher, F. R., Berndt, S. I., Benlloch, S., Ahmed, M., Goh, C., Sheng, X., Zhang, Z., Muir, K., Govindasami, K., Lophatananon, A. & 290 othersStevens, V. L., Gapstur, S. M., Carter, B. D., Tangen, C. M., Goodman, P., Thompson, I. M., Batra, J., Chambers, S., Moya, L., Clements, J., Horvath, L., Tilley, W., Risbridger, G., Gronberg, H., Aly, M., Nordström, T., Pharoah, P., Pashayan, N., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Albanes, D., Weinstein, S., Wolk, A., Hakansson, N., West, C., Dunning, A. M., Burnet, N., Mucci, L., Giovannucci, E., Andriole, G., Cussenot, O., Cancel-Tassin, G., Koutros, S., Freeman, L. E. B., Sorensen, K. D., Orntoft, T. F., Borre, M., Maehle, L., Grindedal, E. M., Neal, D. E., Donovan, J. L., Hamdy, F. C., Martin, R. M., Travis, R. C., Key, T. J., Hamilton, R. J., Fleshner, N. E., Finelli, A., Ingles, S. A., Stern, M. C., Rosenstein, B., Kerns, S., Ostrer, H., Lu, Y. J., Zhang, H. W., Feng, N., Mao, X., Guo, X., Wang, G., Sun, Z., Giles, G. G., Southey, M. C., MacInnis, R. J., Fitzgerald, L. M., Kibel, A. S., Drake, B. F., Vega, A., Gómez-Caamaño, A., Fachal, L., Szulkin, R., Eklund, M., Kogevinas, M., Llorca, J., Castaño-Vinyals, G., Penney, K. L., Stampfer, M., Park, J. Y., Sellers, T. A., Lin, H. Y., Stanford, J. L., Cybulski, C., Wokolorczyk, D., Lubinski, J., Ostrander, E. A., Geybels, M. S., Nordestgaard, B. G., Nielsen, S. F., Weisher, M., Bisbjerg, R., Røder, M. A., Iversen, P., Brenner, H., Cuk, K., Holleczek, B., Maier, C., Luedeke, M., Schnoeller, T., Kim, J., Logothetis, C. J., John, E. M., Teixeira, M. R., Paulo, P., Cardoso, M., Neuhausen, S. L., Steele, L., Ding, Y. C., De Ruyck, K., De Meerleer, G., Ost, P., Razack, A., Lim, J., Teo, S. H., Lin, D. W., Newcomb, L. F., Lessel, D., Gamulin, M., Kulis, T., Kaneva, R., Usmani, N., Slavov, C., Mitev, V., Parliament, M., Singhal, S., Claessens, F., Joniau, S., Van Den Broeck, T., Larkin, S., Townsend, P. A., Aukim-Hastie, C., Gago-Dominguez, M., Castelao, J. E., Martinez, M. E., Roobol, M. J., Jenster, G., Van Schaik, R. H. N., Menegaux, F., Truong, T., Koudou, Y. A., Xu, J., Khaw, K. T., Cannon-Albright, L., Pandha, H., Michael, A., Kierzek, A., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Lindstrom, S., Turman, C., Ma, J., Hunter, D. J., Riboli, E., Siddiq, A., Canzian, F., Kolonel, L. N., Le Marchand, L., Hoover, R. N., Machiela, M. J., Kraft, P., Cook, M., Thwaites, A., Guy, M., Whitmore, I., Morgan, A., Fisher, C., Hazel, S., Livni, N., Spurdle, A., Srinivasan, S., Kedda, M. A., Aitken, J., Gardiner, R., Hayes, V., Butler, L., Taylor, R., Yeadon, T., Eckert, A., Saunders, P., Haynes, A. M., Papargiris, M., Kujala, P., Talala, K., Murtola, T., Taari, K., Dearnaley, D., Barnett, G., Bentzen, S., Elliott, R., Ranu, H., Hicks, B., Vogt, A., Hutchinson, A., Cox, A., Davis, M., Brown, P., George, A., Marsden, G., Lane, A., Lewis, S. J., Berry, C., Kulkarni, G. S., Toi, A., Evans, A., Zlotta, A. R., Van Der Kwast, T. H., Imai, T., Saito, S., Marzec, J., Cao, G., Lin, J., Ling, J., Li, M., Zhao, S. C., Ren, G., Yu, Y., Wu, Y., Wu, J., Zhou, B., Zhang, Y., Li, J., He, W., Guo, J., Pedersen, J., Hopper, J. L., Milne, R., Klim, A., Carballo, A., Lobato-Busto, R., Peleteiro, P., Calvo, P., Aguado, M., Ruiz-Dominguez, J. M., Cecchini, L., Mengual, L., Alcaraz, A., Bustamante, M., Gracia-Lavedan, E., Dierssen-Sotos, T., Gomez-Acebo, I., Pow-Sang, J., Park, H., Zachariah, B., Kluzniak, W., Kolb, S., Klarskov, P., Stegmaier, C., Vogel, W., Herkommer, K., Bohnert, P., Maia, S., Silva, M. P., De Langhe, S., Thierens, H., Tan, M. H., Ong, A. T., Kastelan, Z., Popov, E., Kachakova, D., Mitkova, A., Vlahova, A., Dikov, T., Christova, S., Carracedo, A., Bangma, C., Schroder, F. H., Cenee, S., Tretarre, B., Rebillard, X., Mulot, C., Sanchez, M., Adolfsson, J., Stattin, P., Johansson, J. E., Cavalli-Bjoerkman, C., Karlsson, A., Broms, M., Wu, H., Tillmans, L., Riska, S., Freedman, M., Wiklund, F., Chanock, S., Henderson, B. E., Easton, D. F., Haiman, C. A., Eeles, R. A., Conti, D. V. & Kote-Jarai, Z., Dec 1 2018, In : Nature Communications. 9, 1, 2256.

Research output: Contribution to journalArticle

loci
Meta-Analysis
Prostatic Neoplasms
cancer
magnetic permeability
17 Citations

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

Hui, K. Y., Fernandez-Hernandez, H., Hu, J., Schaffner, A., Pankratz, N., Hsu, N. Y., Chuang, L. S., Carmi, S., Villaverde, N., Li, X., Rivas, M., Levine, A. P., Bao, X., Labrias, P. R., Haritunians, T., Ruane, D., Gettler, K., Chen, E., Li, D., Schiff, E. R. & 31 othersPontikos, N., Barzilai, N., Brant, S. R., Bressman, S., Cheifetz, A. S., Clark, L. N., Daly, M. J., Desnick, R. J., Duerr, R. H., Katz, S., Lencz, T., Myers, R. H., Ostrer, H., Ozelius, L., Payami, H., Peter, Y., Rioux, J. D., Segal, A. W., Scott, W. K., Silverberg, M. S., Vance, J. M., Ubarretxena-Belandia, I., Foroud, T., Atzmon, G., Pe'er, I., Ioannou, Y., McGovern, D. P. B., Yue, Z., Schadt, E. E., Cho, J. H. & Peter, I., Jan 10 2018, In : Science Translational Medicine. 10, 423, eaai7795.

Research output: Contribution to journalArticle

Crohn Disease
Parkinson Disease
Genes
Phosphotransferases
Haplotypes

High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation

Lencz, T., Yu, J., Palmer, C., Carmi, S., Ben-Avraham, D., Barzilai, N., Bressman, S., Darvasi, A., Cho, J. H., Clark, L. N., Gümüş, Z. H., Joseph, V., Klein, R., Lipkin, S., Offit, K., Ostrer, H., Ozelius, L. J., Peter, I., Atzmon, G. & Pe’er, I., Apr 28 2018, (Accepted/In press) In : Human Genetics. p. 1-13 13 p.

Research output: Contribution to journalArticle

Quality Control
Genome
Population
Genomics
Nucleotides
2 Citations

Machine Learning on a Genome-wide Association Study to Predict Late Genitourinary Toxicity After Prostate Radiation Therapy

Lee, S., Kerns, S., Ostrer, H., Rosenstein, B., Deasy, J. O. & Oh, J. H., Jan 1 2018, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

machine learning
genome
Genome-Wide Association Study
toxicity
Prostate