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  • 9 Similar Profiles
HIV-1 Medicine & Life Sciences
HIV Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
HIV Infections Medicine & Life Sciences
SCID Mice Medicine & Life Sciences
Human immunodeficiency virus 1 Agriculture & Biology
Virus Diseases Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences

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Grants 1988 2022

Research
HIV
Research Personnel
Acquired Immunodeficiency Syndrome
Biomarkers

Drugs of abuse and the epigenetic and signaling pathways controlling HIV latency

Goldstein, H., Karn, J., Harvey, B., Ransohoff, R. M., Landreth, G. E., Ransohoff, R. M. & Landreth, G. E.

National Institutes of Health

7/1/133/31/18

Project: Research projectResearch Project

Street Drugs
Epigenomics
HIV
Peroxisome Proliferator-Activated Receptors
Methamphetamine
Systems Biology
HIV Infections
Substance-Related Disorders
HIV
Street Drugs
Therapeutic Uses
HIV
Mutation
Peptides
Cytotoxic T-Lymphocytes

Mechanisms of in vivo protection from HIV infection

Goldstein, H.

National Institutes of Health

3/15/072/28/12

Project: Research projectResearch Project

HIV Infections
HIV
HIV-1
Hematopoietic Stem Cells
Immunity

Publications 1983 2017

  • 2809 Citations
  • 26 h-Index
  • 82 Article
  • 2 Chapter

Potent in vivo NK cellmediated elimination of HIV-1-infected cells mobilized by a gp120-bispecific and hexavalent broadly neutralizing fusion protein

Bardhi, A., Wu, Y., Chen, W., Li, W., Zhu, Z., Zheng, J. H., Wong, H., Jeng, E., Jones, J., Ochsenbauer, C., Kappes, J. C., Dimitrov, D. S., Ying, T. & Goldstein, H. Oct 1 2017 In : Journal of Virology. 91, 20, e00937-17

Research output: Research - peer-reviewArticle

Human immunodeficiency virus 1
neutralization
proteins
cells
HIV-1

T-cell receptor (TCR) clonotype-specific differences in inhibitory activity of HIV-1 cytotoxic T-cell clones is not mediated by TCR alone

Flerin, N. C., Chen, H., Glover, T. D., Lamothe, P. A., Zheng, J. H., Fang, J. W., Ndhlovu, Z. M., Newell, E. W., Davis, M. M., Walker, B. D. & Goldstein, H. 2017 In : Journal of Virology. 91, 6, e02412-16

Research output: Research - peer-reviewArticle

T-Cell Antigen Receptor
HIV-1
Clone Cells
T-Lymphocytes
Human immunodeficiency virus 1
3 Citations

High-throughput humanized mouse models for evaluation of HIV-1 therapeutics and pathogenesis

Thomas, T., Seay, K., Zheng, J. H., Zhang, C., Ochsenbauer, C., Kappes, J. C. & Goldstein, H. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1354, p. 221-235 15 p. (Methods in Molecular Biology; vol. 1354)

Research output: ResearchChapter

HIV-1
Therapeutics
HIV
HIV Infections
Blood Cells
4 Citations

Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1

Chen, W., Bardhi, A., Feng, Y., Wang, Y., Qi, Q., Li, W., Zhu, Z., Dyba, M. A., Ying, T., Jiang, S., Goldstein, H. & Dimitrov, D. S. May 18 2016 In : mAbs. 8, 4, p. 761-774 14 p.

Research output: Research - peer-reviewArticle

HIV-1
Pharmacokinetics
Antibodies
Proteins
Immunoglobulin G
3 Citations

Engineering and exploitation of a fluorescent HIV-1 gp120 for live cell CD4 binding assays

Costantini, L. M., Irvin, S. C., Kennedy, S. C., Guo, F., Goldstein, H., Herold, B. C. & Snapp, E. L. Feb 1 2015 In : Virology. 476, p. 240-248 9 p.

Research output: Research - peer-reviewArticle

HIV-1
Proteins
HIV Envelope Protein gp120
Laser Scanning Cytometry
Anti-HIV Agents