Projects per year
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Dive into the research topics where Edward L. Schwartz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Grants
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Dissecting Skp2 functions in pRb and p53 doubly deficient tumorigenesis
6/3/16 → 5/31/21
Project: Research project
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Interactions of the angiopoietin and PD-ECGF pathways in tumor angiogenesis
Schwartz, E. L., Schwartz, E. L., Rose, S. A. & Rose, S. A.
National Cancer Institute, National Institutes of Health
7/9/12 → 5/31/18
Project: Research project
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Anti-angiogenic actions of taxotere
Schwartz, E. L. & Rose, S. A.
9/29/03 → 6/30/09
Project: Research project
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Mechanisms of thymidine phosphorylase angiogenesis
Schwartz, E. L. & Rose, S. A.
6/1/01 → 4/30/12
Project: Research project
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Publications
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Skp2 Depletion Reduces Tumor-Initiating Properties and Promotes Apoptosis in Synovial Sarcoma
Wang, J., Sato, K., O'Donnell, E., Singla, A., Yaguare, S., Aldahamsheh, O., Batko, B., Borjihan, H., Tingling, J., Zhang, J., Weiser, D. A., Loeb, D. M., Gorlick, R., Schwartz, E. L., Yang, R., Zi, X., Zhao, H., Geller, D. S. & Hoang, B. H., Oct 2020, In: Translational Oncology. 13, 10, 100809.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeted Inhibition of the E3 Ligase SCFSkp2/Cks1 Has Antitumor Activity in RB1-Deficient Human and Mouse Small-Cell Lung Cancer
Zhao, H., Iqbal, N. J., Sukrithan, V., Nicholas, C., Xue, Y., Yu, C., Locker, J., Zou, J., Schwartz, E. L. & Zhu, L., Jun 1 2020, In: Cancer research. 80, 11, p. 2355-2367 13 p.Research output: Contribution to journal › Article › peer-review
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Lysosome membrane permeabilization and disruption of the molecular target of rapamycin (mTOR)-lysosome interaction are associated with the inhibition of lung cancer cell proliferation by a chloroquinoline analog
Sironi, J., Aranda, E., Nordstrøm, L. U. & Schwartz, E. L., Jan 2019, In: Molecular Pharmacology. 95, 1, p. 127-138 12 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Discovery of autophagy inhibitors with antiproliferative activity in lung and pancreatic cancer cells
Nordstrøm, L. U., Sironi, J., Aranda, E., Maisonet, J., Perez-Soler, R., Wu, P. & Schwartz, E. L., Feb 12 2015, In: ACS Medicinal Chemistry Letters. 6, 2, p. 134-139 6 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
RICTOR amplification defines a novel subset of patients with lung cancer who may benefit from treatment with mTORC1/2 inhibitors
Cheng, H., Zou, Y., Ross, J. S., Wang, K., Liu, X., Halmos, B., Ali, S. M., Liu, H., Verma, A., Montagna, C., Chachoua, A., Goel, S., Schwartz, E. L., Zhu, C., Shan, J., Yu, Y., Gritsman, K., Yelensky, R., Lipson, D., Otto, G. & 5 others, , Dec 2015, In: Cancer discovery. 5, 12, p. 1262-1270 9 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations