Projects per year
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Dive into the research topics where Edward L. Schwartz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Grants
- 16 Finished
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Vulnerability of SCLC based on bi-allelic genetic inactivation of RB1 and TP53
4/12/19 → 3/31/22
Project: Research project
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Vulnerability of SCLC based on bi-allelic genetic inactivation of RB1 and TP53
4/12/19 → 3/31/21
Project: Research project
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Dissecting Skp2 functions in pRb and p53 doubly deficient tumorigenesis
6/3/16 → 5/31/21
Project: Research project
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Dissecting Skp2 functions in pRb and p53 doubly deficient tumorigenesis
Schwartz, E. L., Zhao, H. & Zhu, L.
6/3/16 → 5/31/21
Project: Research project
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Interactions of the angiopoietin and PD-ECGF pathways in tumor angiogenesis
Schwartz, E. L., Schwartz, E. L., Rose, S. A. & Rose, S. A.
7/9/12 → 5/31/18
Project: Research project
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Targeting the untargetable: RB1-deficient tumours are vulnerable to Skp2 ubiquitin ligase inhibition
Gupta, P., Zhao, H., Hoang, B. & Schwartz, E. L., Oct 5 2022, In: British Journal of Cancer. 127, 6, p. 969-975 7 p.Research output: Contribution to journal › Article › peer-review
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The interaction of SKP2 with p27 enhances the progression and stemness of osteosarcoma
Wang, J., Aldahamsheh, O., Ferrena, A., Borjihan, H., Singla, A., Yaguare, S., Singh, S., Viscarret, V., Tingling, J., Zi, X., Lo, Y., Gorlick, R., Zheng, D., Schwartz, E. L., Zhao, H., Yang, R., Geller, D. S. & Hoang, B. H., Feb 18 2021, In: Annals of the New York Academy of Sciences. 1490, 1, p. 90-104 15 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Skp2 Depletion Reduces Tumor-Initiating Properties and Promotes Apoptosis in Synovial Sarcoma
Wang, J., Sato, K., O'Donnell, E., Singla, A., Yaguare, S., Aldahamsheh, O., Batko, B., Borjihan, H., Tingling, J., Zhang, J., Weiser, D. A., Loeb, D. M., Gorlick, R., Schwartz, E. L., Yang, R., Zi, X., Zhao, H., Geller, D. S. & Hoang, B. H., Oct 2020, In: Translational Oncology. 13, 10, 100809.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Targeted inhibition of the E3 ligase SCFSkp2/Cks1 has antitumor activity in RB1-deficient human and mouse small-cell lung cancer
Zhao, H., Iqbal, N. J., Sukrithan, V., Nicholas, C., Xue, Y., Yu, C., Locker, J., Zou, J., Schwartz, E. L. & Zhu, L., Jun 2020, In: Cancer research. 80, 11, p. 2355-2367 13 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Lysosome membrane permeabilization and disruption of the molecular target of rapamycin (mTOR)-lysosome interaction are associated with the inhibition of lung cancer cell proliferation by a chloroquinoline analog
Sironi, J., Aranda, E., Nordstrøm, L. U. & Schwartz, E. L., Jan 2019, In: Molecular Pharmacology. 95, 1, p. 127-138 12 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations