• 10394 Citations
  • 44 h-Index
19992020
If you made any changes in Pure, your changes will be visible here soon.

Publications 1999 2019

  • 10394 Citations
  • 44 h-Index
  • 128 Article
  • 2 Comment/debate
  • 1 Chapter
2019
1 Citation (Scopus)
Lenses
Genes
Cell Nucleus
Crystallins
Alleles
1 Citation (Scopus)

Dissection of Merkel cell formation in hairy and glabrous skin reveals a common requirement for FGFR2-mediated signalling

Nguyen, M. B., Valdes, V. J., Cohen, I., Pothula, V., Zhao, D., Zheng, D. & Ezhkova, E., Jan 1 2019, In : Experimental Dermatology.

Research output: Contribution to journalArticle

Merkel Cells
Dissection
Skin
Touch
Transcriptome
1 Citation (Scopus)

GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance

Lee, E., Wongvipat, J., Choi, D., Wang, P., Lee, Y. S., Zheng, D., Watson, P. A., Gopalan, A. & Sawyers, C. L., Jan 15 2019, In : eLife. 8

Research output: Contribution to journalArticle

Androgen Antagonists
Androgen Receptors
Prostatic Neoplasms
Genes
Small Interfering RNA

Non-catalytic Roles of Tet2 Are Essential to Regulate Hematopoietic Stem and Progenitor Cell Homeostasis

Ito, K., Lee, J., Chrysanthou, S., Zhao, Y., Josephs, K., Sato, H., Teruya-Feldstein, J., Zheng, D., Dawlaty, M. M. & Ito, K., Sep 3 2019, In : Cell Reports. 28, 10, p. 2480-2490.e4

Research output: Contribution to journalArticle

Open Access
Hematopoietic Stem Cells
Gene expression
Homeostasis
DNA
Chromatin
1 Citation (Scopus)

PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation

Ren, Z., Ahn, J. H., Liu, H., Tsai, Y. H., Bhanu, N. V., Koss, B., Allison, D. F., Ma, A., Storey, A. J., Wang, P., Mackintosh, S. G., Edmondson, R. D., Groen, R. W. J., Martens, A. C., Garcia, B. A., Tackett, A. J., Jin, J., Cai, L., Zheng, D. & Wang, G. G., Oct 3 2019, In : Blood. 134, 14, p. 1176-1189 14 p.

Research output: Contribution to journalArticle

Polycomb Repressive Complex 2
Multiple Myeloma
Chemical activation
Histones
Chromatin

Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression

Bar, C., Cohen, I., Zhao, D., Pothula, V., Litskevitch, A., Koseki, H., Zheng, D. & Ezhkova, E., Jul 2 2019, In : Cell Reports. 28, 1, p. 257-266.e5

Research output: Contribution to journalArticle

Open Access
Polycomb Repressive Complex 1
Maintenance
Gene expression
Tissue
Tongue
4 Citations (Scopus)

PRC1 preserves epidermal tissue integrity independently of PRC2

Cohen, I., Zhao, D., Menon, G., Nakayama, M., Koseki, H., Zheng, D. & Ezhkova, E., Jan 1 2019, In : Genes & development. 33, 1-2, p. 55-60 6 p.

Research output: Contribution to journalArticle

Polycomb Repressive Complex 1
Skin
Gene Expression
Regulator Genes
Morphogenesis
1 Citation (Scopus)
Open Access
Crystalline Lens
Lenses
Chromatin
Transcription Factors
Nucleosomes
9 Citations (Scopus)

Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers

Zhao, Y., Wilmarth, P. A., Cheng, C., Limi, S., Fowler, V. M., Zheng, D., David, L. L. & Cvekl, A., Feb 1 2019, In : Experimental Eye Research. 179, p. 32-46 15 p.

Research output: Contribution to journalArticle

Gene Expression Profiling
Proteome
Lenses
Epithelium
Proteins

Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells

Ravichandran, M., Lei, R., Tang, Q., Zhao, Y., Lee, J., Ma, L., Chrysanthou, S., Lorton, B. M., Cvekl, A., Shechter, D., Zheng, D. & Dawlaty, M. M., Jan 1 2019, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

Open Access
Gene Regulatory Networks
Retinoids
Embryonic Stem Cells
Stem cells
Genes

Spatiotemporal Gene Coexpression and Regulation in Mouse Cardiomyocytes of Early Cardiac Morphogenesis

Liu, Y., Lu, P., Wang, Y., Morrow, B. E., Zhou, B. & Zheng, D., Aug 6 2019, In : Journal of the American Heart Association. 8, 15, p. e012941

Research output: Contribution to journalArticle

Open Access
Morphogenesis
Cardiac Myocytes
Transcription Factors
Genes
Congenital Heart Defects
2018
9 Citations (Scopus)
Spatio-Temporal Analysis
Lenses
Epithelial Cells
Epithelium
Lens Diseases
3 Citations (Scopus)

Deletion size analysis of 1680 22q11.2DS subjects identifies a new recombination hotspot on chromosome 22q11.2

on behalf of the International Chromosome 22q11.2, International 22q11.2 Brain and Behavior Consortia, Apr 1 2018, In : Human Molecular Genetics. 27, 7, p. 1150-1163 14 p.

Research output: Contribution to journalArticle

DiGeorge Syndrome
Genetic Recombination
Chromosomes
Base Pairing
Genomic Segmental Duplications
5 Citations (Scopus)

Disruption of interneuron neurogenesis in premature newborns and reversal with Estrogen treatment

Tibrewal, M., Cheng, B., Dohare, P., Hu, F., Mehdizadeh, R., Wang, P., Zheng, D., Ungvari, Z. & Ballabh, P., Jan 31 2018, In : Journal of Neuroscience. 38, 5, p. 1100-1113 14 p.

Research output: Contribution to journalArticle

Neurogenesis
Interneurons
Median Eminence
Estrogens
Newborn Infant
2 Citations (Scopus)

Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma

Zhang, Y., Zvi, Y. S., Batko, B., Zaphiros, N., O’Donnell, E. F., Wang, J., Sato, K., Yang, R., Geller, D. S., Koirala, P., Zhang, W., Du, X., Piperdi, S., Liu, Y., Zheng, D., Roth, M., Gill, J., Zhang, J., Ren, T., Gorlick, R. & 2 others, Zi, X. & Hoang, B. H., Dec 1 2018, In : Scientific Reports. 8, 1, 14294.

Research output: Contribution to journalArticle

Osteosarcoma
Down-Regulation
Neoplasm Metastasis
Lung
Cell Line
10 Citations (Scopus)

Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons

Wang, P., Zhao, D., Lachman, H. M. & Zheng, D., Dec 1 2018, In : Translational Psychiatry. 8, 1, 58.

Research output: Contribution to journalArticle

Gene Expression
Neurons
Gene Regulatory Networks
Autism Spectrum Disorder
Single-Cell Analysis

Erratum: Author Correction: REST regulates the cell cycle for cardiac development and regeneration (Nature communications (2017) 8 1 (1979))

Zhang, D., Wang, Y., Lu, P., Wang, P., Yuan, X., Yan, J., Cai, C., Chang, C. P., Zheng, D., Wu, B. & Zhou, B., Jan 12 2018, In : Nature Communications. 9, 1, 1 p.

Research output: Contribution to journalComment/debate

document markup languages
HTML
regeneration
Regeneration
Cell Cycle
12 Citations (Scopus)

FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor

Ran, L., Chen, Y., Sher, J., Wong, E. W. P., Murphy, D., Zhang, J. Q., Li, D., Deniz, K., Sirota, I., Cao, Z., Wang, S., Guan, Y., Shukla, S., Li, K. Y., Chramiec, A., Xie, Y., Zheng, D., Koche, R. P., Antonescu, C. R., Chen, Y. & 1 others, Chi, P., Feb 1 2018, In : Cancer Discovery. 8, 2, p. 234-251 18 p.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Chromatin
Maintenance
Interstitial Cells of Cajal
Cell Lineage

Metabolite differences between glutamate carboxypeptidase II gene knockout mice and their wild-type littermates after traumatic brain injury: a 7-tesla 1H-MRS study

Wu, W., Xu, S., Wang, J., Zhang, K., Zhang, M., Cao, Y., Ren, H., Zheng, D. & Zhong, C., Nov 20 2018, In : BMC Neuroscience. 19, 1, 1 p.

Research output: Contribution to journalArticle

Glutamate Carboxypeptidase II
Gene Knockout Techniques
Knockout Mice
Glutamic Acid
Brain Edema
25 Citations (Scopus)

PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification

Cohen, I., Zhao, D., Bar, C., Valdes, V. J., Dauber-Decker, K. L., Nguyen, M. B., Nakayama, M., Rendl, M., Bickmore, W. A., Koseki, H., Zheng, D. & Ezhkova, E., May 3 2018, In : Cell Stem Cell. 22, 5, p. 726-739.e7

Research output: Contribution to journalArticle

Polycomb Repressive Complex 1
Transcriptional Activation
Stem Cells
Skin
Chromatin
2 Citations (Scopus)

Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation

Diacou, R., Zhao, Y., Zheng, D., Cvekl, A. & Liu, W., Nov 27 2018, In : Cell Reports. 25, 9, p. 2510-2523.e4

Research output: Contribution to journalArticle

Catenins
Maintenance
Gene expression
Retina
Stem Cells

SMARTcleaner: Identify and clean off-target signals in SMART ChIP-seq analysis

Zhao, D. & Zheng, D., Dec 27 2018, In : BMC Bioinformatics. 19, 1, 544.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Chromatin Immunoprecipitation
Chromatin
Sequencing
DNA
14 Citations (Scopus)

Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression

Adam, R. C., Yang, H., Ge, Y., Lien, W. H., Wang, P., Zhao, Y., Polak, L., Levorse, J., Baksh, S. C., Zheng, D. & Fuchs, E., Jan 1 2018, (Accepted/In press) In : Cell Stem Cell.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Hair Follicle
Cell Lineage
Stem Cells
Chromatin
5 Citations (Scopus)

The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells

Xu, B., Cai, L., Butler, J. M., Chen, D., Lu, X., Allison, D. F., Lu, R., Rafii, S., Parker, J. S., Zheng, D. & Wang, G. G., Jan 1 2018, (Accepted/In press) In : Stem Cell Reports.

Research output: Contribution to journalArticle

Adult Stem Cells
Hematopoietic Stem Cells
Stem cells
Gene expression
Chromatin
7 Citations (Scopus)

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer

Cai, L., Tsai, Y. H., Wang, P., Wang, J., Li, D., Fan, H., Zhao, Y., Bareja, R., Lu, R., Wilson, E. M., Sboner, A., Whang, Y. E., Zheng, D., Parker, J. S., Earp, H. S. & Wang, G. G., Oct 18 2018, In : Molecular Cell. 72, 2, p. 341-354.e6

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Androgens
Castration
Therapeutics
2017
17 Citations (Scopus)

Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance

Shukla, S., Cyrta, J., Murphy, D. A., Walczak, E. G., Ran, L., Agrawal, P., Xie, Y., Chen, Y., Wang, S., Zhan, Y., Li, D., Wong, E. W. P., Sboner, A., Beltran, H., Mosquera, J. M., Sher, J., Cao, Z., Wongvipat, J., Koche, R. P., Gopalan, A. & 5 others, Zheng, D., Rubin, M. A., Scher, H. I., Chi, P. & Chen, Y., Dec 11 2017, In : Cancer Cell. 32, 6, p. 792-806.e7

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Androgens
Transcriptome
Chromatin
3 Citations (Scopus)

Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis

Zhao, D., Lin, M., Pedrosa, E., Lachman, H. M. & Zheng, D., Nov 10 2017, In : BMC Genomics. 18, 1, 860.

Research output: Contribution to journalArticle

RNA
Gene Expression
Brain
Genes
Psychiatry
47 Citations (Scopus)

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells

Wang, P., Mokhtari, R., Pedrosa, E., Kirschenbaum, M., Bayrak, C., Zheng, D. & Lachman, H. M., Mar 20 2017, In : Molecular Autism. 8, 1, 11.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Organoids
Induced Pluripotent Stem Cells
Gene Knockout Techniques
Gene Regulatory Networks
8 Citations (Scopus)

Epigenetic and genetic dissections of UV-induced global gene dysregulation in skin cells through multi-omics analyses

Shen, Y., Stanislauskas, M., Li, G., Zheng, D. & Liu, L., Feb 17 2017, In : Scientific Reports. 7, 42646.

Research output: Contribution to journalArticle

Epigenomics
Dissection
Radiation Effects
Radiation
Skin
18 Citations (Scopus)

ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis

Bose, R., Karthaus, W. R., Armenia, J., Abida, W., Iaquinta, P. J., Zhang, Z., Wongvipat, J., Wasmuth, E. V., Shah, N., Sullivan, P. S., Doran, M. G., Wang, P., Patruno, A., Zhao, Y., Zheng, D., Schultz, N. & Sawyers, C. L., Jun 29 2017, In : Nature. 546, 7660, p. 671-675 5 p.

Research output: Contribution to journalArticle

Prostate
Carcinogenesis
Mutation
Neoplasms
Prostatic Neoplasms
7 Citations (Scopus)

Evolutionary origins of Pax6 control of crystallin genes

Cvekl, A., Zhao, Y., Estrada, R. S., Xie, Q., Gu, X. & Zheng, D., 2017, In : Genome Biology and Evolution. 9, 8, p. 2075-2092 18 p.

Research output: Contribution to journalArticle

crystallins
Crystallins
gene
Genes
genes
14 Citations (Scopus)

In Utero Exposure to a High-Fat Diet Programs Hepatic Hypermethylation and Gene Dysregulation and Development of Metabolic Syndrome in Male Mice

Seki, Y., Suzuki, M., Guo, X., Glenn, A. S., Vuguin, P. M., Fiallo, A., Du, Q., Ko, Y. A., Yu, Y., Susztak, K., Zheng, D., Greally, J. M., Katz, E. B. & Charron, M. J., Sep 1 2017, In : Endocrinology. 158, 9, p. 2860-2872 13 p.

Research output: Contribution to journalArticle

High Fat Diet
Metabolic Diseases
Quantitative Trait Loci
Liver
Genes
13 Citations (Scopus)

N-myc regulates growth and fiber cell differentiation in lens development

Cavalheiro, G. R., Matos-Rodrigues, G. E., Zhao, Y., Gomes, A. L., Anand, D., Predes, D., de Lima, S., Abreu, J. G., Zheng, D., Lachke, S. A., Cvekl, A. & Martins, R. A. P., Sep 1 2017, In : Developmental Biology. 429, 1, p. 105-117 13 p.

Research output: Contribution to journalArticle

Lenses
Cell Differentiation
Growth
myc Genes
Morphogenesis
13 Citations (Scopus)

PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs

Zhu, Z., Li, C., Zeng, Y., Ding, J., Qu, Z., Gu, J., Ge, L., Tang, F., Huang, X., Zhou, C., Wang, P., Zheng, D. & Jin, Y., Feb 2 2017, In : Cell Stem Cell. 20, 2, p. 274-289.e7

Research output: Contribution to journalArticle

Epigenomics
Chromatin
Histones
Histone Chaperones
Isocitrate Dehydrogenase
6 Citations (Scopus)

Reduced dosage of β-catenin provides significant rescue of cardiac outflow tract anomalies in a Tbx1 conditional null mouse model of 22q11.2 deletion syndrome

Racedo, S., Hasten, E., Lin, M., Devakanmalai, G. S., Guo, T., Ozbudak, E. M., Cai, C. L., Zheng, D. & Morrow, B. E., Mar 1 2017, In : PLoS Genetics. 13, 3, e1006687.

Research output: Contribution to journalArticle

DiGeorge Syndrome
Catenins
embryo
embryo (animal)
outflow
23 Citations (Scopus)

Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer

Shah, N., Wang, P., Wongvipat, J., Karthaus, W. R., Abida, W., Armenia, J., Rockowitz, S., Drier, Y., Bernstein, B. E., Long, H. W., Freedman, M. L., Arora, V. K., Zheng, D. & Sawyers, C. L., Sep 11 2017, In : eLife. 6, e27861.

Research output: Contribution to journalArticle

Androgen Antagonists
Glucocorticoid Receptors
Prostatic Neoplasms
Androgen Receptors
Drug Resistance
9 Citations (Scopus)

REST regulates the cell cycle for cardiac development and regeneration

Zhang, D., Wang, Y., Lu, P., Wang, P., Yuan, X., Yan, J., Cai, C., Chang, C. P., Zheng, D., Wu, B. & Zhou, B., Dec 1 2017, In : Nature Communications. 8, 1, 2210.

Research output: Contribution to journalArticle

regeneration
Cardiac Myocytes
Regeneration
Cell Cycle
Cells
13 Citations (Scopus)
Rett Syndrome
Macrophage Activation
Microglia
Gene Expression Profiling
Gene Expression
2016
3 Citations (Scopus)

Divergence and rewiring of regulatory networks for neural development between human and other species

Wang, P., Zhao, D., Rockowitz, S. & Zheng, D., Jan 1 2016, In : Neurogenesis. 3, 1, e1231495.

Research output: Contribution to journalComment/debate

Human Development
Genes
Pan troglodytes
Gene Regulatory Networks
Learning Disorders
53 Citations (Scopus)

Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development

Lu, R., Wang, P., Parton, T., Zhou, Y., Chrysovergis, K., Rockowitz, S., Chen, W. Y., Abdel-Wahab, O., Wade, P. A., Zheng, D. & Wang, G. G., Jul 11 2016, In : Cancer Cell. 30, 1, p. 92-107 16 p.

Research output: Contribution to journalArticle

Epigenomics
Leukemia
Stem Cells
Hematopoietic Stem Cells
Gene Expression
23 Citations (Scopus)

Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion

Lin, M., Pedrosa, E., Hrabovsky, A., Chen, J., Puliafito, B. R., Gilbert, S. R., Zheng, D. & Lachman, H. M., Nov 15 2016, In : BMC Systems Biology. 10, 1, 105.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Stem Cells
Network Analysis
Gene Expression Profiling
Electric network analysis
11 Citations (Scopus)

Loss of MEN1 activates DNMT1 implicating DNA hypermethylation as a driver of MEN1 tumorigenesis

Yuan, Z., Claros, C. S., Suzuki, M., Maggi, E. C., Kaner, J. D., Kinstlinger, N., Gorecka, J., Quinn, T. J., Geha, R., Corn, A., Pastoriza, J., Jing, Q., Adem, A., Wu, H., Alemu, G., Du, Y. C., Zheng, D., Greally, J. M. & Libutti, S. K., Mar 15 2016, In : Oncotarget. 7, 11, p. 12633-12650 18 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Carcinogenesis
DNA
Retinoblastoma Binding Proteins
Multiple Endocrine Neoplasia
44 Citations (Scopus)

MYOSLID is a novel serum response factor-dependent long noncoding RNA that amplifies the vascular smooth muscle differentiation program

Zhao, J., Zhang, W., Lin, M., Wu, W., Jiang, P., Tou, E., Xue, M., Richards, A., Jourd'heuil, D., Asif, A., Zheng, D., Singer, H. A., Miano, J. M. & Long, X., Oct 1 2016, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 10, p. 2088-2099 12 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Serum Response Factor
Vascular Smooth Muscle
Smooth Muscle
Smooth Muscle Myocytes
13 Citations (Scopus)

Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts

Zhang, D., Wu, B., Wang, P., Wang, Y., Lu, P., Nechiporuk, T., Floss, T., Greally, J. M., Zheng, D. & Zhou, B., 2016, In : Nucleic Acids Research. 45, 6, p. 3102-3115 14 p.

Research output: Contribution to journalArticle

Gene Silencing
Methylation
Transcription Factors
Transcriptional Silencer Elements
Genes
14 Citations (Scopus)

Pangolin genomes and the evolution of mammalian scales and immunity

Choo, S. W., Rayko, M., Tan, T. K., Hari, R., Komissarov, A., Wee, W. Y., Yurchenko, A. A., Kliver, S., Tamazian, G., Antunes, A., Wilson, R. K., Warren, W. C., Koepfli, K. P., Minx, P., Krasheninnikova, K., Kotze, A., Dalton, D. L., Vermaak, E., Paterson, I. C., Dobrynin, P. & 12 others, Sitam, F. T., Rovie-Ryan, J. J., Johnson, W. E., Yusoff, A. M., Luo, S. J., Karuppannan, K. V., Fang, G., Zheng, D., Gerstein, M. B., Lipovich, L., O'Brien, S. J. & Wong, G. J., Oct 1 2016, In : Genome Research. 26, 10, p. 1312-1322 11 p.

Research output: Contribution to journalArticle

Interferons
Immunity
Odorant Receptors
Genome
Mucosal Immunity
11 Citations (Scopus)

Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers

Sun, J., Zhao, Y., Estrada, R. S., Cohen-Tayar, Y., Rockowitz, S., Wilczek, C., Ashery-Padan, R., Shechter, D., Zheng, D. & Cvekl, A., Sep 9 2016, In : Epigenetics and Chromatin. 9, 1, 37.

Research output: Contribution to journalArticle

Methylation
Lenses
Post Translational Protein Processing
Chromatin
Histones
20 Citations (Scopus)

Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development

Perdigoto, C. N., Dauber, K. L., Bar, C., Tsai, P. C., Valdes, V. J., Cohen, I., Santoriello, F. J., Zhao, D., Zheng, D., Hsu, Y. C. & Ezhkova, E., Jul 1 2016, In : PLoS Genetics. 12, 7, e1006151.

Research output: Contribution to journalArticle

Merkel Cells
Erinaceidae
hair
skin (animal)
skin
14 Citations (Scopus)

Reduced CYFIP1 in human neural progenitors results in dysregulation of schizophrenia and epilepsy gene networks

Nebel, R. A., Zhao, D., Pedrosa, E., Kirschen, J., Lachman, H. M., Zheng, D. & Abrahams, B. S., Jan 1 2016, In : PLoS One. 11, 1, 0148039.

Research output: Contribution to journalArticle

epilepsy
Gene Regulatory Networks
Epilepsy
Schizophrenia
Genes
17 Citations (Scopus)

RNA-seq identification of RACGAP1 as a metastatic driver in uterine carcinosarcoma

Mi, S., Lin, M., Brouwer-Visser, J., Heim, J., Smotkin, D., Hebert, T. M., Gunter, M. J., Goldberg, G. L., Zheng, D. & Huang, G. S., Sep 15 2016, In : Clinical Cancer Research. 22, 18, p. 4676-4686 11 p.

Research output: Contribution to journalArticle

rac GTP-Binding Proteins
Carcinosarcoma
GTPase-Activating Proteins
RNA
Atlases
2015
93 Citations (Scopus)

Alternative transcription initiation leads to expression of a novel ALK isoform in cancer

Wiesner, T., Lee, W., Obenauf, A. C., Ran, L., Murali, R., Zhang, Q. F., Wong, E. W. P., Hu, W., Scott, S. N., Shah, R. H., Landa, I., Button, J., Lailler, N., Sboner, A., Gao, D., Murphy, D. A., Cao, Z., Shukla, S., Hollmann, T. J., Wang, L. & 12 others, Borsu, L., Merghoub, T., Schwartz, G. K., Postow, M. A., Ariyan, C. E., Fagin, J. A., Zheng, D., Ladanyi, M., Busam, K. J., Berger, M. F., Chen, Y. & Chi, P., Oct 15 2015, In : Nature. 526, 7573, p. 453-457 5 p.

Research output: Contribution to journalArticle

Protein Isoforms
Neoplasms
Transcription Initiation Site
Oncogenes
anaplastic lymphoma kinase