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David M. Loeb, Ph.D., M.D.

  • 3214 Citations
  • 29 h-Index
1986 …2019
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  • 17 Similar Profiles
Neoplasms Medicine & Life Sciences
Ewing's Sarcoma Medicine & Life Sciences
Sarcoma Medicine & Life Sciences
Osteosarcoma Medicine & Life Sciences
Pediatrics Medicine & Life Sciences
Nerve Growth Factor Medicine & Life Sciences
Wilms' Tumor Genes Medicine & Life Sciences
Cyclophosphamide Medicine & Life Sciences

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Grants 2013 2019

Comb External Beam Radiotherapy with 153Sm-EDTMP to Treat High Risk Osteosarcoma

Loeb, D. M.

National Institutes of Health

6/1/13 → 3/31/19

Project: Research project

Comb and Wattles
Osteosarcoma
Radiotherapy
Radiopharmaceuticals
Radiation

Publications 1986 2018

3 Citations (Scopus)

Association of dasatinib with progression-free survival among patients with advanced gastrointestinal stromal tumors resistant to imatinib

Schuetze, S. M., Bolejack, V., Thomas, D. G., Von Mehren, M., Patel, S., Samuels, B., Choy, E., D'Amato, G., Staddon, A. P., Ganjoo, K. N., Chow, W. A., Rushing, D. A., Forscher, C. A., Priebat, D. A., Loeb, D. M., Chugh, R., Okuno, S., Reinke, D. K. & Baker, L. H., Jun 1 2018, In : JAMA oncology. 4, 6, p. 814-820 7 p.

Research output: Contribution to journal › Article

Gastrointestinal Stromal Tumors
Disease-Free Survival
Neoplasms
Platelet-Derived Growth Factor Receptors
Sarcoma
14 Citations (Scopus)

Consensus and controversies regarding the treatment of rhabdomyosarcoma

Borinstein, S. C., Steppan, D., Hayashi, M., Loeb, D. M., Isakoff, M. S., Binitie, O., Brohl, A. S., Bridge, J. A., Stavas, M., Shinohara, E. T., Meyer, W. H., Reed, D. R. & Wagner, L. M., Feb 1 2018, In : Pediatric Blood and Cancer. 65, 2, e26809.

Research output: Contribution to journal › Review article

Rhabdomyosarcoma
Patient Care
Standard of Care
Sarcoma
Young Adult

Knock-In of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice

Annesley, C. E., Rabik, C., Duffield, A. S., Rau, R. E., Magoon, D., Li, L., Huff, V., Small, D., Loeb, D. M. & Brown, P., Oct 1 2018, In : Oncotarget. 9, 82, p. 35313-35326 14 p.

Research output: Contribution to journal › Article

Myelodysplastic Syndromes
Wilms Tumor
Mutation
Neoplasms
Karyotype
8 Citations (Scopus)

Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with Chimerism Studies and Wilms Tumor 1 Gene Expression

Jacobsohn, D. A., Loken, M. R., Fei, M., Adams, A., Brodersen, L. E., Logan, B. R., Ahn, K. W., Shaw, B. E., Kletzel, M., Olszewski, M., Khan, S., Meshinchi, S., Keating, A., Harris, A., Teira, P., Duerst, R. E., Margossian, S. P., Martin, P. L., Petrovic, A., Dvorak, C. C. & 29 others, Nemecek, E. R., Boyer, M. W., Chen, A. R., Davis, J. H., Shenoy, S., Savasan, S., Hudspeth, M. P., Adams, R. H., Lewis, V. A., Kheradpour, A., Kasow, K. A., Gillio, A. P., Haight, A. E., Bhatia, M., Bambach, B. J., Haines, H. L., Quigg, T. C., Greiner, R. J., Talano, J. A. M., Delgado, D. C., Cheerva, A., Gowda, M., Ahuja, S., Ozkaynak, M., Mitchell, D., Schultz, K. R., Fry, T. J., Loeb, D. M. & Pulsipher, M. A., Jan 1 2018, (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journal › Article

Wilms' Tumor Genes
Chimerism
Wilms Tumor
Hematopoietic Stem Cells
Acute Myeloid Leukemia

Three-dimensional in vitro modeling of malignant bone disease recapitulates experimentally accessible mechanisms of osteoinhibition

McNeill, E. P., Reese, R. W., Tondon, A., Clough, B. H., Pan, S., Froese, J., Palmer, D., Krause, U., Loeb, D. M., Kaunas, R. & Gregory, C. A., Dec 1 2018, In : Cell Death and Disease. 9, 12, 1161.

Research output: Contribution to journal › Article

Bone Diseases
Mesenchymal Stromal Cells
Bone and Bones
Neoplasms
Heterografts