Physiology & Biophysics

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Heme Chemical Compounds
Hemoglobins Medicine & Life Sciences
Carbon Monoxide Chemical Compounds
Membranes Medicine & Life Sciences
Microtubules Medicine & Life Sciences
Sickle Hemoglobin Medicine & Life Sciences
Ligands Medicine & Life Sciences
Oxygen Medicine & Life Sciences

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Projects 1975 2020

X ray crystallography
Microfluidics
Electron Transport Complex IV
Reaction intermediates
Microcrystals
Dioxygenases
Tryptophan
Neurodegenerative diseases
Kynurenine
Enzymes

MECHANISM OF MICROTUBULE DYNAMICS REGULATION BY KINESINS

Sosa, H. J.

National Institutes of Health

3/1/152/28/19

Project: Research projectResearch Project

Kinesin
Microtubules
Tubulin
Polymers
Centrioles

Research Output 1965 2018

Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s

Benoit, M. P. M. H., Asenjo, A. B. & Sosa, H. Dec 1 2018 In : Nature Communications. 9, 1, 1662

Research output: Contribution to journalArticle

depolymerization
Kinesin
Microtubules
nucleotides
Reactor startup
Rotary engines
Hydroxylysine
Ketoglutarate Dehydrogenase Complex
Citric Acid Cycle
Tryptophan

The mitochondrial 2-oxoadipate and 2-oxoglutarate dehydrogenase complexes share their E2 and E3 components for their function and both generate reactive oxygen species

Nemeria, N. S., Gerfen, G., Nareddy, P. R., Yang, L., Zhang, X., Szostak, M. & Jordan, F. Feb 1 2018 In : Free Radical Biology and Medicine. 115, p. 136-145 10 p.

Research output: Contribution to journalArticle

Ketoglutarate Dehydrogenase Complex
Thiamine Pyrophosphate
Reactive Oxygen Species
Oxidoreductases
Decarboxylation