Albert Einstein College of Medicine

Research Output 1960 2019

2019

(At Least) Once in Her Lifetime: Global Cervical Cancer Prevention

Castle, P. E. & Pierz, A., Mar 1 2019, In : Obstetrics and Gynecology Clinics of North America. 46, 1, p. 107-123 17 p.

Research output: Contribution to journalReview article

Uterine Cervical Neoplasms
Vaccination
Costs and Cost Analysis

3D Printing and Heart Failure: The Present and the Future

Farooqi, K. M., Cooper, C., Chelliah, A., Saeed, O., Chai, P. J., Jambawalikar, S. R., Lipson, H., Bacha, E. A., Einstein, A. J. & Jorde, U. P., Feb 1 2019, In : JACC: Heart Failure. 7, 2, p. 132-142 11 p.

Research output: Contribution to journalReview article

Heart Failure
Heart Diseases
Patient Care
Technology
Three Dimensional Printing

Abdominal Approach to Vesicovaginal Fistula

McKay, E., Watts, K. L. & Abraham, N. E., Feb 1 2019, In : Urologic Clinics of North America. 46, 1, p. 135-146 12 p.

Research output: Contribution to journalReview article

Vesicovaginal Fistula
Urinary Bladder
Operative Time
Laparoscopy
Fistula

A cross-sectional analysis of dietary protein intake and body composition among Chinese Americans

Popp, C. J., Beasley, J. M., Yi, S. S., Hu, L. & Wylie-Rosett, J., Jan 1 2019, In : Journal of Nutritional Science.

Research output: Contribution to journalArticle

Asian Americans
protein bodies
Dietary Proteins
Body Composition
protein intake

Acute glufosinate-based herbicide treatment in rats leads to increased ocular interleukin-1β and c-Fos protein levels, as well as intraocular pressure

Çomaklı, S., Sevim, Ç., Kontadakis, G., Doğan, E., Taghizadehghalehjoughi, A., Özkaraca, M., Aschner, M., Nikolouzakis, T. K. & Tsatsakis, A., Jan 1 2019, In : Toxicology Reports. 6, p. 155-160 6 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-fos
Herbicides
Intraocular Pressure
Interleukin-1beta
Rats

A National Analysis on Predictors of Discharge to Rehabilitation After Corrective Surgery for Adolescent Idiopathic Scoliosis

De la Garza Ramos, R., Nakhla, J., Echt, M., Schulz, J. F., Gomez, J. A., Cho, W. & Yassari, R., Jan 15 2019, In : Spine. 44, 2, p. 118-122 5 p.

Research output: Contribution to journalArticle

Scoliosis
Rehabilitation
Hospital Charges
Length of Stay
Odds Ratio

Anticoagulation after catheter ablation of atrial fibrillation: An unnecessary evil? A systematic review and meta-analysis

Proietti, R., AlTurki, A., Di Biase, L., China, P., Forleo, G., Corrado, A., Marras, E., Natale, A. & Themistoclakis, S., Jan 1 2019, (Accepted/In press) In : Journal of cardiovascular electrophysiology.

Research output: Contribution to journalArticle

Catheter Ablation
Atrial Fibrillation
Meta-Analysis
Odds Ratio
Confidence Intervals

Antitumoral effects of attenuated Listeria monocytogenes in a genetically engineered mouse model of melanoma

Vitiello, M., Evangelista, M., Di Lascio, N., Kusmic, C., Massa, A., Orso, F., Sarti, S., Marranci, A., Rodzik, K., Germelli, L., Chandra, D., Salvetti, A., Pucci, A., Taverna, D., Faita, F., Gravekamp, C. & Poliseno, L., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Listeria monocytogenes
Melanoma
Listeria
Heterografts
Neoplasms

Anxious and Overwhelming Affects and Repetitive Negative Thinking as Ecological Predictors of Self-Injurious Thoughts and Behaviors

Hughes, C. D., King, A. M., Kranzler, A., Fehling, K., Miller, A., Lindqvist, J. & Selby, E. A., Jan 1 2019, (Accepted/In press) In : Cognitive Therapy and Research.

Research output: Contribution to journalArticle

Self-Injurious Behavior
Wounds and Injuries
Health
Pessimism
Young Adult
2 Citations

APOE Alleles and Extreme Human Longevity

Sebastiani, P., Gurinovich, A., Nygaard, M., Sasaki, T., Sweigart, B., Bae, H., Andersen, S. L., Villa, F., Atzmon, G., Christensen, K., Arai, Y., Barzilai, N., Puca, A., Christiansen, L., Hirose, N. & Perls, T. T., Jan 1 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 1, p. 44-51 8 p.

Research output: Contribution to journalArticle

Alleles
Genotype
Population
New England
Retirement

Approach to the Child with Hematuria

Brown, D. D. & Reidy, K. J., Feb 1 2019, In : Pediatric Clinics of North America. 66, 1, p. 15-30 16 p.

Research output: Contribution to journalReview article

Hematuria
Glomerulonephritis
IGA Glomerulonephritis
Hypercalciuria
Proteinuria
Clinical Decision Support Systems
Proton Therapy
Oropharyngeal Neoplasms
Quality-Adjusted Life Years
Head and Neck Neoplasms

Arrhythmogenecity and thrombogenecity of the residual left atrial appendage stump following surgical exclusion of the appendage in patients with atrial fibrillation

Mohanty, S., Di Biase, L., Trivedi, C., Choudhury, F., Della Rocca, D. G., Romero, J. E., Gianni, C., Sanchez, J., Hranitzky, P., Gallinghouse, G. J., Al-Ahmad, A., Horton, R. P., Burkhardt, D. & Natale, A., Jan 1 2019, (Accepted/In press) In : Journal of cardiovascular electrophysiology.

Research output: Contribution to journalArticle

Atrial Appendage
Atrial Fibrillation
Veins
Anti-Arrhythmia Agents
Smoke

Association Between Plasma Antibody Responses and Risk for Cryptococcus-Associated Immune Reconstitution Inflammatory Syndrome

Yoon, H. A., Nakouzi, A., Chang, C. C., Kuniholm, M. H., Carreño, L. J., Wang, T., Ndung'u, T., Lewin, S. R., French, M. A. & Pirofski, L., Jan 9 2019, In : The Journal of infectious diseases. 219, 3, p. 420-428 9 p.

Research output: Contribution to journalArticle

Immune Reconstitution Inflammatory Syndrome
Cryptococcus
Antibody Formation
Immunoglobulin M
Immunoglobulin G
1 Citations

Association of Biomarker and Physiologic Indices With Mortality in Older Adults: Cardiovascular Health Study

Sanders, J. L., Arnold, A. M., Boudreau, R. M., Hirsch, C. H., Kizer, J., Kaplan, R. C., Cappola, A. R., Cushman, M., Jacob, M. E., Kritchevsky, S. B. & Newman, A. B., Jan 1 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 1, p. 114-120 7 p.

Research output: Contribution to journalArticle

Biomarkers
Mortality
Health
Proportional Hazards Models
Phenotype

Association of Magnetic Resonance Imaging and a 12-Gene Expression Assay with Breast Ductal Carcinoma in Situ Treatment

Lehman, C. D., Gatsonis, C., Romanoff, J., Khan, S. A., Carlos, R., Solin, L. J., Badve, S., McCaskill-Stevens, W., Corsetti, R. L., Rahbar, H., Spell, D. W., Blankstein, K. B., Han, L. K., Sabol, J. L., Bumberry, J. R., Gareen, I., Snyder, B. S., Wagner, L. I., Miller, K. D., Sparano, J. A. & 1 othersComstock, C., Jan 1 2019, (Accepted/In press) In : JAMA Oncology.

Research output: Contribution to journalArticle

Carcinoma, Intraductal, Noninfiltrating
Magnetic Resonance Imaging
Gene Expression
Mastectomy
Radiotherapy

Associations between fine particulate matter and changes in lipids/lipoproteins among midlife women

Wu, X. M., Broadwin, R., Basu, R., Malig, B., Ebisu, K., Gold, E. B., Qi, L., Derby, C. A., Park, S. K. & Green, S., Mar 1 2019, In : Science of the Total Environment. 654, p. 1179-1186 8 p.

Research output: Contribution to journalArticle

Lipoproteins
Particulate Matter
Lipids
particulate matter
lipid

Associations between SLC16A11 variants and diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Hidalgo, B. A., Sofer, T., Qi, Q., Schneiderman, N., Chen, Y. D. I., Kaplan, R. C., Avilés-Santa, M. L., North, K. E., Arnett, D. K., Szpiro, A., Cai, J., Yu, B., Boerwinkle, E., Papanicolaou, G., Laurie, C. C., Rotter, J. I. & Stilp, A. M., Dec 1 2019, In : Scientific reports. 9, 1, 843.

Research output: Contribution to journalArticle

Hispanic Americans
Health
Haplotypes
Single Nucleotide Polymorphism
Genetic Research

Associations of Insulin Resistance and Glycemia With Liver Enzymes in Hispanic/Latino Youths: Results From the Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth)

Parrinello, C. M., Rudolph, B. J., Lazo, M., Gallo, L. C., Thyagarajan, B., Cotler, S. J., Qi, Q., Seeherunvong, T., Vidot, D. C., Strickler, H., Kaplan, R. C. & Isasi, C. R., Feb 1 2019, In : Journal of clinical gastroenterology. 53, 2, p. e46-e53

Research output: Contribution to journalArticle

Hispanic Americans
Insulin Resistance
Aspartate Aminotransferases
Liver
Enzymes

Axon-Dependent Patterning and Maintenance of Somatosensory Dendritic Arbors

Ramirez-Suarez, N. J., Belalcazar, H. M., Salazar, C. J., Beyaz, B., Raja, B., Nguyen, K. C. Q., Celestrin, K., Fredens, J., Færgeman, N. J., Hall, D. H. & Buelow, H. E., Jan 28 2019, In : Developmental cell. 48, 2, p. 229-244.e4

Research output: Contribution to journalArticle

Dendrites
Axons
Maintenance
Physical vapor deposition
Neurons

BCL-2 Protein Family Interaction Analysis by Nuclear Magnetic Resonance Spectroscopy

Garner, T. P. & Gavathiotis, E., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 217-231 15 p. (Methods in Molecular Biology; vol. 1877).

Research output: Chapter in Book/Report/Conference proceedingChapter

Magnetic Resonance Spectroscopy
Proteins
Biomolecular Nuclear Magnetic Resonance

Belinostat, at Its Clinically Relevant Concentrations, Inhibits Rifampicin-Induced CYP3A4 and MDR1 Gene Expression

Abbott, K. L., Chaudhury, C. S., Chandran, A., Vishveshwara, S., Dvorak, Z., Jiskrova, E., Poulikova, K., Vyhlidalova, B., Mani, S. & Pondugula, S. R., Mar 1 2019, In : Molecular pharmacology. 95, 3, p. 324-334 11 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Rifampin
Gene Expression
irinotecan
Combination Drug Therapy
4 Citations

Biatrial maze procedure versus pulmonary vein isolation for atrial fibrillation during mitral valve surgery: New analytical approaches and end points

Cardiothoracic Surgical Trials Network Investigators, Jan 1 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 1, p. 234-243.e9

Research output: Contribution to journalArticle

Pulmonary Veins
Mitral Valve
Atrial Fibrillation
Atrial Flutter
Tachycardia
Lenses
Genes
Cell Nucleus
Crystallins
Alleles

Biofilm Inhibition via Delivery of Novel Methylthioadenosine Nucleosidase Inhibitors from PVA-Tyramine Hydrogels while Supporting Mesenchymal Stromal Cell Viability

Mutreja, I., Warring, S. L., Lim, K. S., Swadi, T., Clinch, K., Mason, J. M., Sheen, C. R., Thompson, D. R., Ducati, R. G., Chambers, S. T., Evans, G. B., Gerth, M. L., Miller, A. G. & Woodfield, T. B. F., Jan 1 2019, (Accepted/In press) In : ACS Biomaterials Science and Engineering.

Research output: Contribution to journalArticle

Tyramine
Hydrogels
Biofilms
Cells
Hydrogel

Blockade of CTLA-4 and Tim-3 pathways induces fetal loss with altered cytokine profiles by decidual CD4+T cells

Wang, S., Chen, C., Li, M., Qian, J., Sun, F., Li, Y., Yu, M., Wang, M., Zang, X., Zhu, R., Li, D. & Du, M., Jan 1 2019, In : Cell Death and Disease. 10, 1, 15.

Research output: Contribution to journalArticle

Mucin-3
Cytotoxic T-Lymphocytes
Immunoglobulins
Cytokines
T-Lymphocytes

Cancer-associated stroke: Pathophysiology, detection and management (Review)

Dardiotis, E., Aloizou, A. M., Markoula, S., Siokas, V., Tsarouhas, K., Tzanakakis, G., Libra, M., Kyritsis, A. P., Brotis, A. G., Aschner, M., Gozes, I., Bogdanos, D. P., Spandidos, D. A., Mitsias, P. D. & Tsatsakis, A., Mar 1 2019, In : International journal of oncology. 54, 3, p. 779-796 18 p.

Research output: Contribution to journalReview article

Stroke
Neoplasms
Fibrin Fibrinogen Degradation Products
Low Molecular Weight Heparin
Tissue Plasminogen Activator

Cerebellar modulation of the reward circuitry and social behavior

Carta, I., Chen, C. H., Schott, A. L., Dorizan, S. & Khodakhah, K., Jan 18 2019, In : Science. 363, 6424, eaav0581.

Research output: Contribution to journalArticle

Ventral Tegmental Area
Social Behavior
Reward
Cerebellum
Optogenetics

CHAPTER 9: Structure, Function and Regulation of Human Heme-based Dioxygenases

Lewis-Ballester, A., Pham, K. N., Liao, M., Correia, M. A. & Yeh, S-R., Jan 1 2019, Dioxygen-dependent Heme Enzymes. Ikeda-Saito, M. & Raven, E. (eds.). 13 ed. Royal Society of Chemistry, p. 181-221 41 p. (RSC Metallobiology; vol. 2019-January, no. 13).

Research output: Chapter in Book/Report/Conference proceedingChapter

Dioxygenases
Indoleamine-Pyrrole 2,3,-Dioxygenase
Heme
Protons
Tryptophan

Chromatin Characterization in Xenopus laevis Cell-Free Egg Extracts and Embryos

Wang, W. L., Onikubo, T. & Shechter, D., Feb 1 2019, In : Cold Spring Harbor protocols. 2019, 2

Research output: Contribution to journalArticle

Histone Code
Xenopus laevis
Histones
Chromatin
Ovum

Closure of foramen ovale triggered by injury to tunnel surfaces of septum primum and secundum

Di Biase, L., Burkhardt, J. D., Horton, R., Sanchez, J., Mohanty, P., Mohanty, S., Bailey, S., Gallinghouse, G. J., Natale, A. & Krishnan, S. C., Jan 1 2019, In : Journal of Interventional Cardiac Electrophysiology.

Research output: Contribution to journalArticle

Foramen Ovale
Patent Foramen Ovale
Wounds and Injuries
Stroke Volume
Atrial Fibrillation

Combined Endocardial-Epicardial Versus Endocardial Catheter Ablation Alone for Ventricular Tachycardia in Structural Heart Disease: A Systematic Review and Meta-Analysis

Romero, J. E., Cerrud-Rodriguez, R. C., Di Biase, L., Diaz, J. C., Alviz, I., Grupposo, V., Cerna, L., Avendano, R., Tedrow, U., Natale, A., Tung, R. & Kumar, S., Jan 1 2019, In : JACC: Clinical Electrophysiology. 5, 1, p. 13-24 12 p.

Research output: Contribution to journalArticle

Catheter Ablation
Ventricular Tachycardia
Meta-Analysis
Cardiomyopathies
Heart Diseases

Commentary response for “LARC provision by family physicians: Low but on the rise”

Gold, M., Jan 1 2019, In : Journal of the American Board of Family Medicine. 32, 1, p. 4-5 2 p.

Research output: Contribution to journalComment/debate

Family Physicians

Comprehensive Analysis of Stroke in the Long-Term Cohort of the MOMENTUM 3 Study

Colombo, P. C., Mehra, M. R., Goldstein, D. J., Estep, J. D., Salerno, C., Jorde, U. P., Cowger, J. A., Cleveland, J. C., Uriel, N., Sayer, G., Skipper, E. R., Downey, F. X., Ono, M., Hooker, R., Anyanwu, A. C., Givertz, M. M., Mahr, C., Topuria, I., Somo, S. I., Crandall, D. L. & 1 othersHorstmanshof, D. A., Jan 8 2019, In : Circulation. 139, 2, p. 155-168 14 p.

Research output: Contribution to journalArticle

Stroke
Equipment and Supplies
Heart-Assist Devices
Survival
Multicenter Studies
Colicins
Endonucleases
immunity
dissociation
proteins

Correction: Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model (Arthritis Research and Therapy (2014) 16 (508) DOI: 10.1186/s13075-014-0508-y)

Leong, D. J., Choudhury, M., Hanstein, R., Hirsh, D. M., Kim, S. J., Majeska, R. J., Schaffler, M. B., Hardin, J. A., Spray, D. C., Goldring, M. B., Cobelli, N. J. & Sun, H. H., Jan 3 2019, In : Arthritis Research and Therapy. 21, 1, 1791.

Research output: Contribution to journalComment/debate

Ficus
Polyphenols
Tea
Osteoarthritis
Arthritis

CT/MR LI-RADS 2018: clinical implications and management recommendations

Kamath, A., Roudenko, A., Hecht, E., Sirlin, C., Chernyak, V., Fowler, K. & Mitchell, D. G., Jan 1 2019, (Accepted/In press) In : Abdominal Radiology.

Research output: Contribution to journalArticle

Information Systems
Hepatocellular Carcinoma
Liver
Neoplasms
Biopsy

Cumulative Human Immunodeficiency Viremia, Antiretroviral Therapy, and Incident Myocardial Infarction

Delaney, J. A., Nance, R. M., Whitney, B. M., Crane, H. M., Williams-Nguyen, J., Feinstein, M. J., Kaplan, R. C., Hanna, D. B., Budoff, M. J., Drozd, D. R., Burkholder, G., Mugavero, M. J., Mathews, W. C., Moore, R. D., Eron, J. J., Hunt, P. W., Geng, E., Saag, M. S., Kitahata, M. M. & Heckbert, S. R., Jan 1 2019, In : Epidemiology (Cambridge, Mass.). 30, 1, p. 69-74 6 p.

Research output: Contribution to journalArticle

Viremia
Myocardial Infarction
Viral Load
Confidence Intervals
Therapeutics

Deceased-donor acute kidney injury is not associated with kidney allograft failure

Hall, I. E., Akalin, E., Bromberg, J. S., Doshi, M. D., Greene, T., Harhay, M. N., Jia, Y., Mansour, S. G., Mohan, S., Muthukumar, T., Reese, P. P., Schröppel, B., Singh, P., Thiessen-Philbrook, H. R., Weng, F. L. & Parikh, C. R., Jan 1 2019, In : Kidney international. 95, 1, p. 199-209 11 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Renal Insufficiency
Allografts
Tissue Donors
Graft Survival

Decellularized bovine placentome for portacavally-interposed heterotopic liver transplantation in rats

Kakabadze, Z., Karalashvili, L., Chakhunashvili, D., Havlioglu, N., Janelidze, M., Kakabadze, A., Sharma, Y. & Gupta, S., Apr 1 2019, In : Materials Science and Engineering C. 97, p. 293-301 9 p.

Research output: Contribution to journalArticle

transplantation
liver
Liver
rats
Rats
Dementia
Depression
Independent Living
Incidence
Proportional Hazards Models

Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase

Winters, M., DuHadaway, J. B., Pham, K. N., Lewis-Ballester, A., Badir, S., Wai, J., Sheikh, E., Yeh, S-R., Prendergast, G. C., Muller, A. J. & Malachowski, W. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 455-464 10 p.

Research output: Contribution to journalArticle

Hydroxylamines
Indoleamine-Pyrrole 2,3,-Dioxygenase
Dioxygenases
Tryptophan
Enzymes

Differential responses to spectrally degraded speech within human auditory cortex: An intracranial electrophysiology study

Nourski, K. V., Steinschneider, M., Rhone, A. E., Kovach, C. K., Kawasaki, H. & Howard, M. A., Jan 1 2019, In : Hearing Research. 371, p. 53-65 13 p.

Research output: Contribution to journalArticle

Auditory Cortex
Electrophysiology
Cochlear Implants
Temporal Lobe
Noise

Digital Pancreaticocholangioscopy for Mapping of Pancreaticobiliary Neoplasia: Can We Alter the Surgical Resection Margin?

Tyberg, A., Raijman, I., Siddiqui, A., Arnelo, U., Adler, D. G., Xu, M. M., Nassani, N., Sejpal, DI. V., Kedia, P., Nah Lee, Y., Gress, F. G., Ho, S., Gaidhane, M. & Kahaleh, M., Jan 1 2019, In : Journal of Clinical Gastroenterology. 53, 1, p. 71-75 5 p.

Research output: Contribution to journalArticle

Neoplasms
Endoscopic Retrograde Cholangiopancreatography
Pancreatic Ducts
Bile Ducts
Margins of Excision

Disability in inflammatory bowel disease patients is associated with race, ethnicity and socio-economic factors

Agrawal, M., Cohen-Mekelburg, S., Kayal, M., Axelrad, J., Galati, J., Tricomi, B., Kamal, K., Faye, A. S., Abrudescu, P., Scherl, E., Lawlor, G., Sultan, K., Lukin, D. J., Colombel, J. F. & Ungaro, R. C., Jan 1 2019, (Accepted/In press) In : Alimentary Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Economics
Odds Ratio
Confidence Intervals
Hispanic Americans

Discharge Heart Rate After Hospitalization for Myocardial Infarction and Long-Term Mortality in 2 US Registries

Alapati, V., Tang, F., Charlap, E., Chan, P. S., Heidenreich, P. A., Jones, P. G., Spertus, J. A., Srinivas, V. & Kizer, J., Feb 5 2019, In : Journal of the American Heart Association. 8, 3, p. e010855

Research output: Contribution to journalArticle

Registries
Hospitalization
Heart Rate
Myocardial Infarction
Mortality

Editorial

Aschner, M., Autrup, H. N., Cohen, S. M., Dekant, W., Eisenbrand, G., Galli, C. L., Gori, G. B., Kaminski, N. E., Klaassen, C. D., Klaunig, J. E., Levy, L., Lotti, M., Marquardt, H. WJ., Pelkonen, O., Schrenk, D. F. & Yamazaki, H., Feb 1 2019, In : Regulatory Toxicology and Pharmacology. 101, p. A1-A2

Research output: Contribution to journalEditorial

Effect of Mental Health Screening and Integrated Mental Health on Adolescent Depression–Coded Visits

Rinke, M. L., German, M., Azera, B., Heo, M., Brown, N. M., Gross, R. S., Bundy, D. G., Racine, A. D., Duonnolo, C. & Briggs, R. D., Jan 1 2019, (Accepted/In press) In : Clinical Pediatrics.

Research output: Contribution to journalArticle

Mental Health
Depression
Primary Health Care
Odds Ratio
Confidence Intervals

Effects of onabotulinumtoxinA treatment in chronic migraine patients with and without daily headache at baseline: Results from the COMPEL Study

Young, W. B., Ivan Lopez, J., Rothrock, J. F., Orejudos, A., Manack Adams, A., Lipton, R. B. & Blumenfeld, A. M., Feb 1 2019, In : Journal of Headache and Pain. 20, 1, 12.

Research output: Contribution to journalArticle

Migraine Disorders
Headache
Therapeutics
Quality of Life
onabotulinumtoxinA