TY - JOUR
T1 - Transient neutropenia induced by intravenous immune globulin
AU - Ben-Chetrit, Eldad
AU - Putterman, Chaim
AU - Grebenau, Mark D.
PY - 1992/1/23
Y1 - 1992/1/23
N2 - To the Editor: Intravenous immune globulin is used as an immunomodulatory agent in various autoimmune diseases.1 Adverse effects are uncommon but may include vasomotor symptoms such as chills, nausea, flushing, tightness of the chest, and wheezing.2 Hemolysis, thrombosis, alopecia, and liver-function disturbances have also been reported.3 4 5 Recently, we encountered a 36-year-old woman with active systemic lupus erythematosus in whom treatment with prednisone (60 mg daily) and azathioprine (200 mg daily) had failed to control the manifestations of the disease. Therefore, we decided to attempt a trial of immune globulin (Sandoglobulin, Sandoz), given in two courses (400 mg per kilogram of. . .
AB - To the Editor: Intravenous immune globulin is used as an immunomodulatory agent in various autoimmune diseases.1 Adverse effects are uncommon but may include vasomotor symptoms such as chills, nausea, flushing, tightness of the chest, and wheezing.2 Hemolysis, thrombosis, alopecia, and liver-function disturbances have also been reported.3 4 5 Recently, we encountered a 36-year-old woman with active systemic lupus erythematosus in whom treatment with prednisone (60 mg daily) and azathioprine (200 mg daily) had failed to control the manifestations of the disease. Therefore, we decided to attempt a trial of immune globulin (Sandoglobulin, Sandoz), given in two courses (400 mg per kilogram of. . .
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U2 - 10.1056/NEJM199201233260413
DO - 10.1056/NEJM199201233260413
M3 - Letter
C2 - 1727981
AN - SCOPUS:0026337229
SN - 0028-4793
VL - 326
SP - 270
EP - 271
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 4
ER -