神经眼科学最新研究

Translated title of the contribution: Recent developments in neuro-ophthalmology

Research output: Contribution to journalArticle

Abstract

Some recent advances in neuro-ophthalmology including clinical trials, diagnostic testing and newly elucidated disease entitites were summarized in present paper, such as neuromyelitis optica spectrum disorder.The review goes into great detail regarding recent clinical trials in neuro-ophthalmology.These trials have investigated the management of idiopathic intracranial hypertension as well as treatment of Leber hereditary optic neuropathy and optic nerve glioma.The potential gene therapy for Leber hereditary optic neuropathy seems very promising and may have a significant clinical impact within the next few years.This review also includes an extensive discussion about the application of optical coherence tomography (OCT) and OCT-angiography (OCTA) in neuro-ophthalmology.OCT has important clinical relevance not only for the diagnosis and management of optic neuropathies, such as optic neuritis, ischemic optic neuropathy and chiasmal compression, but also for retro-chiasmal injury.In terms of OCTA, recent studies have demonstrated increased vessel density in acute stage of ischemic optic neuropathy (NAION) and optic neuritis, but decreased vessel density in severe papilloedema and late stage of optic atrophy of any cause.These serve as the potential foundation for future clinical applications.Ophthalmologists should pay more attentions to these recent progress in neuro-ophthalmology.

Translated title of the contributionRecent developments in neuro-ophthalmology
Original languageChinese
Pages (from-to)55-62
Number of pages8
JournalZhonghua Shiyan Yanke Zazhi/Chinese Journal of Experimental Ophthalmology
Volume37
Issue number1
DOIs
StatePublished - Jan 10 2019

Keywords

  • Clinical trials, intracranial hypertension
  • Ischemic optic neuropathy
  • Leber's optic neuropathy
  • Neuro-ophthalmology
  • Optic neuritis
  • Optical coherence tomography
  • Optical coherence tomography angiography

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'Recent developments in neuro-ophthalmology'. Together they form a unique fingerprint.

  • Cite this