Fertility in persons with epilepsy: 1935-1974

Mayris P. Webber, W. A. Hauser, R. Ottman, J. F. Annegers

Research output: Contribution to journalArticle

125 Citations (Scopus)

Abstract

Data from the Rochester-Olmsted County Medical Records Linkage Project were utilized to assess fertility in persons with epilepsy. Population age-specific reproduction rates for Rochester residents for the years 1935-1974 were estimated using the number of live births from the Minnesota Department of Health Statistics and Vital Statistics of the U.S. for comparison with rates in affected persons. Overall, fertility rates were significantly reduced to 80% of expected for affected males and 85% for affected females. Individuals with partial seizures (simple and complex) were disadvantaged, whereas those with generalized onset were not. During the last 20 years of the study period, males were more disadvantaged than females. The male-female difference was greatest during the time of low population fertility (after 1965). Male deficits were more marked after diagnosis; female deficits were more marked before diagnosis. Differences in the proportion of ever-married person-years between the sexes only partially explain the observed differences.

Original languageEnglish (US)
Pages (from-to)746-752
Number of pages7
JournalEpilepsia
Volume27
Issue number6
StatePublished - 1986
Externally publishedYes

Fingerprint

Fertility
Epilepsy
Vulnerable Populations
Medical Record Linkage
Vital Statistics
Partial Epilepsy
Birth Rate
Live Birth
Spouses
Population
Reproduction
Health

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Webber, M. P., Hauser, W. A., Ottman, R., & Annegers, J. F. (1986). Fertility in persons with epilepsy: 1935-1974. Epilepsia, 27(6), 746-752.

Fertility in persons with epilepsy : 1935-1974. / Webber, Mayris P.; Hauser, W. A.; Ottman, R.; Annegers, J. F.

In: Epilepsia, Vol. 27, No. 6, 1986, p. 746-752.

Research output: Contribution to journalArticle

Webber, MP, Hauser, WA, Ottman, R & Annegers, JF 1986, 'Fertility in persons with epilepsy: 1935-1974', Epilepsia, vol. 27, no. 6, pp. 746-752.
Webber MP, Hauser WA, Ottman R, Annegers JF. Fertility in persons with epilepsy: 1935-1974. Epilepsia. 1986;27(6):746-752.
Webber, Mayris P. ; Hauser, W. A. ; Ottman, R. ; Annegers, J. F. / Fertility in persons with epilepsy : 1935-1974. In: Epilepsia. 1986 ; Vol. 27, No. 6. pp. 746-752.
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