Aim: Evaluate the influence of puberty in oxidative stress. Subjects and methods: The study included 38 prepubescent males with Tanner G1-P1 and 32 healthy pubescent boys with Tanner G3-4-P3-4. Weight, height and body mass index, heart rate, blood pressure values were with in the 50 percentile 50±1SD for their age. The biomarkers were measured in saliva, as a good correlation between saliva and plasma levels has been reported in lipoperoxidation products, reduced glutathione and catalase. Results: Pubescent boys had significantly higher levels of lipoperoxidation products (P<0.001) compared with the prepubertal group, with no significant differences in the other parameters measured. There was a significant positive correlation between lipoperoxides and reduced glutathione in these children. Conclusion: It is the first time that an increase of lipoperoxidation products has been reported inpubertal boys and this biomarker could playarole in the development of oxidative stress in this stage of life.
- Lipoperoxidation products
- Oxidative stress
- Reduced glutathione
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health