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• Active surveillance of metastatic renal cell carcinoma: Results from a prospective observational study (MaRCC)

  Harrison, M. R., Costello, B. A., Bhavsar, N. A., Vaishampayan, U., Pal, S. K., Zakharia, Y., Jim, H. S. L., Fishman, M. N., Molina, A. M., Kyriakopoulos, C. E., Tsao, C. K., Appleman, L. J., Gartrell, B. A., Hussain, A., Stadler, W. M., Agarwal, N., Pachynski, R. K., Hutson, T. E., Hammers, H. J., Ryan, C. W. & 4 others, Inman, B. A., Mardekian, J., Borham, A. & George, D. J., Jul 1 2021, In: Cancer. 127, 13, p. 2204-2212 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Scopus citations

• Active site structure of the aa₃ quinol oxidase of Acidianus ambivalens

  Das, T. K., Gomes, C. M., Bandeiras, T. M., Pereira, M. M., Teixeira, M. & Rousseau, D. L., Apr 12 2004, In: Biochimica et Biophysica Acta - Bioenergetics. 1655, 1-3, p. 306-320 15 p.

  Research output: Contribution to journal › Review article › peer-review
  17 Scopus citations

• Active site residues in Mycobacterium tuberculosis pantothenate synthetase required in the formation and stabilization of the adenylate intermediate

  Zheng, R., Dam, T. K., Brewer, C. F. & Blanchard, J. S., Jun 8 2004, In: Biochemistry. 43, 22, p. 7171-7178 8 p.

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• Active site loop motion in triosephosphate isomerase: T-jump relaxation spectroscopy of thermal activation

  Desamero, R., Rozovsky, S., Zhadin, N., McDermott, A. & Callender, R., Mar 18 2003, In: Biochemistry. 42, 10, p. 2941-2951 11 p.

  Research output: Contribution to journal › Article › peer-review
  83 Scopus citations

• Active-Site Glu165 Activation in Triosephosphate Isomerase and Its Deprotonation Kinetics

  Deng, H., Dyer, R. B. & Callender, R., May 16 2019, In: Journal of Physical Chemistry B. 123, 19, p. 4230-4241 12 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Active site contacts in the purine nucleoside phosphorylase-hypoxanthine complex by NMR and ab initio calculations

  Deng, H., Cahill, S. M., Abad, J. L., Lewandowicz, A., Callender, R. H., Schramm, V. L. & Jones, R. A., Dec 21 2004, In: Biochemistry. 43, 50, p. 15966-15974 9 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Active site and remote contributions to catalysis in methylthioadenosine nucleosidases

  Thomas, K., Cameron, S. A., Almo, S. C., Burgos, E. S., Gulab, S. A. & Schramm, V. L., Apr 21 2015, In: Biochemistry. 54, 15, p. 2520-2529 10 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Active Rho kinase associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells

  Begum, N., Sandu, O. A., Ito, M., Lohmann, SM. & Smolenski, A., Feb 2002, In: Journal of Biological Chemistry.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  139 Scopus citations

• Active peripheral inflammation is associated with pro-atherogenic lipid profile in psoriatic arthritis

  Shrestha, A., Bahce-Altuntas, A., Mowrey, W. & Broder, A., Dec 1 2016, In: Seminars in Arthritis and Rheumatism. 46, 3, p. 286-290 5 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Active-Loop Dynamics within the Michaelis Complex of Lactate Dehydrogenase from Bacillus stearothermophilus

  Nie, B., Lodewyks, K., Deng, H., Desamero, R. Z. B. & Callender, R., Jul 12 2016, In: Biochemistry. 55, 27, p. 3803-3814 12 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Active interstitial remodeling: An important process in the hibernating human myocardium

  Frangogiannis, N. G., Shimoni, S., Chang, S. M., Ren, G., Dewald, O., Gersch, C., Shan, K., Aggeli, C., Reardon, M., Letsou, G. V., Espada, R., Ramchandani, M., Entman, M. L. & Zoghbi, W. A., May 1 2002, In: Journal of the American College of Cardiology. 39, 9, p. 1468-1474 7 p.

  Research output: Contribution to journal › Article › peer-review
  94 Scopus citations

• Active dendrites and differential distribution of calcium channels enable functional compartmentalization of golgi cells

  Rudolph, S., Hull, C. & Regehr, W. G., Nov 25 2015, In: Journal of Neuroscience. 35, 47, p. 15492-15504 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Scopus citations

• Active currents regulate sensitivity and dynamic range in C. elegans Neurons

  Goodman, M. B., Hall, D. H., Avery, L. & Lockery, S. R., Apr 1998, In: Neuron. 20, 4, p. 763-772 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  266 Scopus citations

• Active contribution of dendrites to the tonic and trimodal patterns of activity in cerebellar Purkinje neurons

  Womack, M. & Khodakhah, K., Dec 15 2002, In: Journal of Neuroscience. 22, 24, p. 10603-10612 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  145 Scopus citations

• Active Commuting to School, Physical Activity, and Behavior Problems Among Third-Grade Children

  Mann, M., Silver, E. J. & Stein, R. E. K., Oct 1 2018, In: Journal of School Health. 88, 10, p. 734-743 10 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Active cigarette smoking and the risk of breast cancer: A cohort study

  Catsburg, C., Kirsh, V. A., Soskolne, C. L., Kreiger, N. & Rohan, T. E., Aug 2014, In: Cancer Epidemiology. 38, 4, p. 376-381 6 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Active cigarette smoking and risk of breast cancer

  Catsburg, C., Miller, A. B. & Rohan, T. E., May 1 2015, In: International Journal of Cancer. 136, 9, p. 2204-2209 6 p.

  Research output: Contribution to journal › Article › peer-review
  65 Scopus citations

• Active case finding: Comparison of the acceptability, feasibility and effectiveness of targeted versus blanket provider-initiated-testing and counseling of HIV among children and adolescents in Cameroon

  Yumo, H. A., Kuaban, C., Ajeh, R. A., Nji, A. M., Nash, D., Kathryn, A., Beissner, M. & Loescher, T., Sep 25 2018, In: BMC Pediatrics. 18, 1, 309.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Activation timecourse of ventral visual stream object-recognition areas: High density electrical mapping of perceptual closure processes

  Doniger, G. M., Foxe, J. J., Murray, M. M., Higgins, B. A., Snodgrass, J. G., Schroeder, C. E. & Javitt, D. C., 2000, In: Journal of cognitive neuroscience. 12, 4, p. 615-621 7 p.

  Research output: Contribution to journal › Article › peer-review
  203 Scopus citations

• Activation of two new α(1,3)fucosyltransferase activities in Chinese hamster ovary cells by 5-azacytidine

  Potvin, B. & Stanley, P., Dec 1991, In: Molecular biology of the cell. 2, 12, p. 989-1000 12 p.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations

• Activation of tumor cell matrix metalloproteinase-2 by neutrophil proteinases requires expression of membrane-type 1 matrix metalloproteinase

  Schwartz, J. D., Shamamian, P., Monea, S., Whiting, D., Marcus, S. G., Galloway, A. C., Mignatti, P. & Nackman, G. B., 1998, In: Surgery. 124, 2, p. 232-238 7 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• Activation of transcription factors AP-1 and NF-κB in murine chagasic myocarditis

  Huang, H., Petkova, S. B., Cohen, A. W., Bouzahzah, B., Chan, J., Zhou, J. N., Factor, S. M., Weiss, L. M., Krishnamachary, M., Mukherjee, S., Wittner, M., Kitsis, R. N., Pestell, R. G., Lisanti, M. P., Albanese, C. & Tanowitz, H. B., May 1 2003, In: Infection and immunity. 71, 5, p. 2859-2867 9 p.

  Research output: Contribution to journal › Article › peer-review
  62 Scopus citations

• Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents

  Mani, S., Huang, H., Sundarababu, S., Liu, W., Kalpana, G., Smith, A. B. & Horwitz, S. B., Sep 1 2005, In: Clinical Cancer Research. 11, 17, p. 6359-6369 11 p.

  Research output: Contribution to journal › Article › peer-review
  63 Scopus citations

• Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP

  Huang, X., Meng, B., Iqbal, J., Ding, B. B., Perry, A. M., Cao, W., Smith, L. M., Bi, C., Jiang, C., Greiner, T. C., Weisenburger, D. D., Rimsza, L., Rosenwald, A., Ott, G., Delabie, J., Campo, E., Braziel, R. M., Gascoyne, R. D., Cook, J. R., Tubbs, R. R. & 8 others, Jaffe, E. S., Armitage, J. O., Vose, J. M., Staudt, L. M., McKeithan, T. W., Chan, W. C., Ye, B. H. & Fu, K., Dec 30 2013, In: Journal of Clinical Oncology. 31, 36, p. 4520-4528 9 p.

  Research output: Contribution to journal › Article › peer-review
  95 Scopus citations

• Activation of the renal renin-angiotensin system by cyclosporine A and FK 506 in the rat

  Kupferman, J. C., Beaudoin, R., Carr, R., Hay, D., Casellas, D., Kaskel, F. J. & Moore, L. C., Nov 7 1994, In: Transplantation Proceedings. 26, 5, p. 2891-2893 3 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress

  Lander, H. M., Tauras, J. M., Ogiste, J. S., Hori, O., Moss, R. A. & Schmidt, A. M., 1997, In: Journal of Biological Chemistry. 272, 28, p. 17810-17814 5 p.

  Research output: Contribution to journal › Article › peer-review
  668 Scopus citations

• Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase Kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma

  Yang, R., Piperdi, S. & Gorlick, R., Oct 15 2008, In: Clinical Cancer Research. 14, 20, p. 6396-6404 9 p.

  Research output: Contribution to journal › Article › peer-review
  50 Scopus citations

• Activation of the phosphoinositide-3-kinase and mammalian target of rapamycin signaling pathways are associated with shortened survival in patients with malignant peritoneal mesothelioma

  Varghese, S., Chen, Z., Bartlett, D. L., Pingpank, J. F., Libutti, S. K., Steinberg, S. M., Wunderlich, J. & Alexander, H. R., Jan 15 2011, In: Cancer. 117, 2, p. 361-371 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  47 Scopus citations

• Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-β on normal hematopoiesis

  Verma, A., Deb, D. K., Sassano, A., Uddin, S., Varga, J., Wickrema, A. & Platanias, L. C., Mar 8 2002, In: Journal of Biological Chemistry. 277, 10, p. 7726-7735 10 p.

  Research output: Contribution to journal › Article › peer-review
  148 Scopus citations

• Activation of the p38 Map kinase pathway is essential for the antileukemic effects of dasatinib

  Dumka, D., Puri, P., Carayol, N., Lumby, C., Balachandran, H., Schuster, K., Verma, A. K., Terada, L. S., Platanias, L. C. & Parmar, S., Dec 2009, In: Leukemia and Lymphoma. 50, 12, p. 2017-2029 13 p.

  Research output: Contribution to journal › Article › peer-review
  38 Scopus citations

• Activation of the low oxygen affinity-inducing potential of the Asn108(β)→Lys mutation of Hb-Presbyterian on intramolecular αα-fumaryl cross-bridging

  Manjula, B. N., Malavalli, A., Prabhakaran, M., Friedman, J. M. & Acharya, A. S., 2001, In: Protein Engineering. 14, 5, p. 359-366 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Scopus citations

• Activation of the K_ATPchannel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH

  Liu, Y. J., Cheng, H., Drought, H., MacDonald, M. J., Sharp, G. W. G. & Straub, S. G., Aug 1 2003, In: American Journal of Physiology - Endocrinology and Metabolism. 285, 2 48-2, p. E380-E389

  Research output: Contribution to journal › Article › peer-review
  50 Scopus citations

• Activation of the Ig Iα1 promoter by the transcription factor Ets-1 triggers Ig Iα1-Cα1 germline transcription in epithelial cancer cells

  Duan, Z., Zheng, H., Xu, S., Jiang, Y., Liu, H., Li, M., Hu, D., Li, W., Bode, A. M., Dong, Z. & Cao, Y., Mar 2014, In: Cellular and Molecular Immunology. 11, 2, p. 197-205 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  20 Scopus citations

• Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II

  Zvara, A., Fajardo, J. E., Escalante, M., Cotton, G., Muir, T., Kirsch, K. H. & Birge, R. B., Feb 22 2001, In: Oncogene. 20, 8, p. 951-961 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  33 Scopus citations

• Activation of the dorsal, but not the ventral, hippocampus relieves neuropathic pain in rodents

  Wei, X., Centeno, M. V., Ren, W., Borruto, A. M., Procissi, D., Xu, T., Jabakhanji, R., Mao, Z., Kim, H., Li, Y., Yang, Y., Gutruf, P., Rogers, J. A., Surmeier, D. J., Radulovic, J., Liu, X., Martina, M. & Apkarian, A. V., Dec 1 2021, In: Pain. 162, 12, p. 2865-2880 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Scopus citations

• Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis

  Albanese, C., D'Amico, M., Reutens, A. T., Fu, M., Watanabe, G., Lee, R. J., Kitsis, R. N., Henglein, B., Avantaggiati, M., Somasundaram, K., Thimmapaya, B. & Pestell, R. G., Nov 26 1999, In: Journal of Biological Chemistry. 274, 48, p. 34186-34195 10 p.

  Research output: Contribution to journal › Article › peer-review
  170 Scopus citations

• Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

  Zhang, Z., Lee, J. C., Lin, L., Olivas, V., Au, V., Laframboise, T., Abdel-Rahman, M., Wang, X., Levine, A. D., Rho, J. K., Choi, Y. J., Choi, C. M., Kim, S. W., Jang, S. J., Park, Y. S., Kim, W. S., Lee, D. H., Lee, J. S., Miller, V. A., Arcila, M. & 10 others, Ladanyi, M., Moonsamy, P., Sawyers, C., Boggon, T. J., Ma, P. C., Costa, C., Taron, M., Rosell, R., Halmos, B. & Bivona, T. G., Aug 2012, In: Nature Genetics. 44, 8, p. 852-860 9 p.

  Research output: Contribution to journal › Article › peer-review
  855 Scopus citations

• Activation of the ARC^POMC→MeA Projection Reduces Food Intake

  Kwon, E. & Jo, Y. H., Nov 5 2020, In: Frontiers in Neural Circuits. 14, 595783.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations

• Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo: Role of mitochondrial reactive nitrogen species

  Zou, M. H., Kirkpatrick, S. S., Davis, B. J., Nelson, J. S., Wiles IV, W. G., Schlattner, U., Neumann, D., Brownlee, M., Freeman, M. B. & Goldman, M. H., Oct 15 2004, In: Journal of Biological Chemistry. 279, 42, p. 43940-43951 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  413 Scopus citations

• Activation of the alternative complement pathway by fungal melanins

  Rosas, Á. L., MacGill, R. S., Nosanchuk, J. D., Kozel, T. R. & Casadevall, A., 2002, In: Clinical and Diagnostic Laboratory Immunology. 9, 1, p. 144-148 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  44 Scopus citations

• Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake

  Jeong, J. H., Lee, D. K., Liu, S. M., Chua, S. C., Schwartz, G. J. & Jo, Y. H., Apr 24 2018, In: PLoS biology. 16, 4, e2004399.

  Research output: Contribution to journal › Article › peer-review
  35 Scopus citations

• Activation of signal transducer and activator of transcription-3 in the spinal cord of sporadic amyotrophic lateral sclerosis patients

  Shibata, N., Kakita, A., Takahashi, H., Ihara, Y., Nobukuni, K., Fujimura, H., Sakoda, S., Sasaki, S., Iwata, M., Morikawa, S., Hirano, A. & Kobayashi, M., May 2009, In: Neurodegenerative Diseases. 6, 3, p. 118-126 9 p.

  Research output: Contribution to journal › Article › peer-review
  30 Scopus citations

• Activation of septal OXTr neurons induces anxiety- but not depressive-like behaviors

  Huang, T., Guan, F., Licinio, J., Wong, M. L. & Yang, Y., Dec 2021, In: Molecular Psychiatry. 26, 12, p. 7270-7279 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Activation of resorption in fatigue-loaded bone involves both apoptosis and active pro-osteoclastogenic signaling by distinct osteocyte populations

  Kennedy, O. D., Herman, B. C., Laudier, D. M., Majeska, R. J., Sun, H. B. & Schaffler, M. B., May 2012, In: Bone. 50, 5, p. 1115-1122 8 p.

  Research output: Contribution to journal › Article › peer-review
  190 Scopus citations

• Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide

  Verma, A., Mohindru, M., Deb, D. K., Sassano, A., Kambhampati, S., Ravandi, F., Minucci, S., Kalvakolanul, D. V. & Platanias, L. C., Nov 22 2002, In: Journal of Biological Chemistry. 277, 47, p. 44988-44995 8 p.

  Research output: Contribution to journal › Article › peer-review
  100 Scopus citations

• Activation of PXR by Alpinetin Contributes to Abrogate Chemically Induced Inflammatory Bowel Disease

  Yu, Z., Yue, B., Ding, L., Luo, X., Ren, Y., Zhang, J., Mani, S., Wang, Z. & Dou, W., Apr 21 2020, In: Frontiers in Pharmacology. 11, 474.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Scopus citations

• Activation of protein kinase Cδ by IFN-γ

  Deb, D. K., Sassano, A., Lekmine, F., Majchrzak, B., Verma, A., Kambhampati, S., Uddin, S., Rahman, A., Fish, E. N. & Platanias, L. C., Jul 1 2003, In: Journal of Immunology. 171, 1, p. 267-273 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  111 Scopus citations

• Activation of protein kinase Cδ by all-trans-retinoic acid

  Kambhampati, S., Li, Y., Verma, A., Sassano, A., Majchrzak, B., Deb, D. K., Parmar, S., Giafis, N., Kalvakolanu, D. V., Rahman, A., Uddin, S., Minucci, S., Tallman, M. S., Fish, E. N. & Platanias, L. C., Aug 29 2003, In: Journal of Biological Chemistry. 278, 35, p. 32544-32551 8 p.

  Research output: Contribution to journal › Article › peer-review
  97 Scopus citations

• Activation of progelatinase A (MMP-2) by neutrophil elastase, cathepsin G, and proteinase-3: A role for inflammatory cells in tumor invasion and angiogenesis

  Shamamian, P., Schwartz, J. D., Pocock, B. J. Z., Monea, S., Whiting, D., Marcus, S. G. & Mignatti, P., 2001, In: Journal of Cellular Physiology. 189, 2, p. 197-206 10 p.

  Research output: Contribution to journal › Article › peer-review
  278 Scopus citations

• Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

  Li, W., Khor, T. O., Xu, C., Shen, G., Jeong, W. S., Yu, S. & Kong, A. N., Dec 1 2008, In: Biochemical Pharmacology. 76, 11, p. 1485-1489 5 p.

  Research output: Contribution to journal › Article › peer-review
  554 Scopus citations