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  Structural Study of a Flexible Active Site Loop in Human Indoleamine 2,3-Dioxygenase and Its Functional Implications

  Álvarez, L., Lewis-Ballester, A., Roitberg, A., Estrin, D. A., Yeh, S. R., Marti, M. A. & Capece, L., May 17 2016, In: Biochemistry. 55, 19, p. 2785-2793 9 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Structural symmetry: The three-dimensional structure of Haemophilus influenzae diaminopimelate epimerase

  Cirilli, M., Zheng, R., Scapin, G. & Blanchard, J. S., Nov 24 1998, In: Biochemistry. 37, 47, p. 16452-16458 7 p.

  Research output: Contribution to journal › Article › peer-review
  70 Scopus citations

• Structural transformations in the dynamics of Michaelis complex formation in lactate dehydrogenase

  McClendon, S., Vu, D. M., Clinch, K., Callender, R. & Dyer, R. B., Jul 2005, In: Biophysical journal. 89, 1, p. L07-L09

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• Structural Underpinnings of Nitrogen Regulation by the Prototypical Nitrogen-Responsive Transcriptional Factor NrpR

  Wisedchaisri, G., Dranow, D. M., Lie, T. J., Bonanno, J. B., Patskovsky, Y., Ozyurt, S. A., Sauder, J. M., Almo, S. C., Wasserman, S. R., Burley, S. K., Leigh, J. A. & Gonen, T., Nov 10 2010, In: Structure. 18, 11, p. 1512-1521 10 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Structural visualization of the p53/RNA polymerase II assembly

  Singh, S. K., Qiao, Z., Song, L., Jani, V., Rice, W., Eng, E., Coleman, R. A. & Liu, W-L., Nov 15 2016, In: Genes and Development. 30, 22, p. 2527-2537 11 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex

  Sampathkumar, P., Kim, S. J., Upla, P., Rice, W. J., Phillips, J., Timney, B. L., Pieper, U., Bonanno, J. B., Fernandez-Martinez, J., Hakhverdyan, Z., Ketaren, N. E., Matsui, T., Weiss, T. M., Stokes, D. L., Sauder, J. M., Burley, S. K., Sali, A., Rout, M. P. & Almo, S. C., Apr 2 2013, In: Structure. 21, 4, p. 560-571 12 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Structure, Evolutionary Conservation, and Conformational Dynamics of Homo sapiens Fascin-1, an F-actin Crosslinking Protein

  Sedeh, R. S., Fedorov, A. A., Fedorov, E. V., Ono, S., Matsumura, F., Almo, S. C. & Bathe, M., Jul 2010, In: Journal of Molecular Biology. 400, 3, p. 589-604 16 p.

  Research output: Contribution to journal › Article › peer-review
  59 Scopus citations

• Structure, expression, and properties of an atypical protein kinase C (PKC3) from Caenorhabditis elegans. PKC3 is required for the normal progression of embryogenesis and viability of the organism

  Wu, S. L., Staudinger, J., Olson, E. N. & Rubin, C. S., Jan 9 1998, In: Journal of Biological Chemistry. 273, 2, p. 1130-1143 14 p.

  Research output: Contribution to journal › Article › peer-review
  33 Scopus citations

• Structure, expression, and regulation of the kilC operon of promiscuous IncPα plasmids

  Larsen, M. H. & Figurski, D. H., 1994, In: Journal of Bacteriology. 176, 16, p. 5022-5032 11 p.

  Research output: Contribution to journal › Article › peer-review
  45 Scopus citations

• Structure, Function, and Applications of the Georgetown–Einstein (GE) Breast Cancer Simulation Model

  Schechter, C. B., Near, A. M., Jayasekera, J., Chandler, Y. & Mandelblatt, J. S., Apr 1 2018, In: Medical Decision Making. 38, 1_suppl, p. 66S-77S

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases

  Yu, X., Sun, J. P., He, Y., Guo, X., Liu, S., Zhou, B., Hudmon, A. & Zhang, Z. Y., Dec 11 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 50, p. 19767-19772 6 p.

  Research output: Contribution to journal › Article › peer-review
  119 Scopus citations

• Structure, mechanism, and substrate profile for Sco3058: The closest bacterial homologue to human renal dipeptidase

  Cummings, J. A., Nguyen, T. T., Fedorov, A. A., Kolb, P., Xu, C., Fedorov, E. V., Shoichet, B. K., Barondeau, D. P., Almo, S. C. & Raushel, F. M., Jan 26 2010, In: Biochemistry. 49, 3, p. 611-622 12 p.

  Research output: Contribution to journal › Article › peer-review
  14 Scopus citations

• Structure/function analysis of the transmembrane domain of DAB₃₈₉- interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells

  VanderSpek, J. C., Mindell, J. A., Finkelstein, A. & Murphy, J. R., 1993, In: Journal of Biological Chemistry. 268, 16, p. 12077-12082 6 p.

  Research output: Contribution to journal › Article › peer-review
  53 Scopus citations

• Structure-activity profiles of eleutherobin analogs and their cross- resistance in Taxol-resistant cell lines

  McDaid, H. M., Bhattacharya, S. K., Chen, X. T., He, L., Shen, H. J., Gutteridge, C. E., Horwitz, S. B. & Danishefsky, S. J., 1999, In: Cancer Chemotherapy and Pharmacology. 44, 2, p. 131-137 7 p.

  Research output: Contribution to journal › Article › peer-review
  41 Scopus citations

• Structure-activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction

  Franco, J. L., Posser, T., Missau, F., Pizzolatti, M. G., Santos, A. R. S., Souza, D. O., Aschner, M., Rocha, J. B. T., Dafre, A. L. & Farina, M., Nov 2010, In: Environmental Toxicology and Pharmacology. 30, 3, p. 272-278 7 p.

  Research output: Contribution to journal › Article › peer-review
  59 Scopus citations

• Structure-activity relationships for propane oxidative dehydrogenation by anatase-supported vanadium oxide monomers and dimers

  Cheng, L., Ferguson, G. A., Zygmunt, S. A. & Curtiss, L. A., Jun 2013, In: Journal of Catalysis. 302, p. 31-36 6 p.

  Research output: Contribution to journal › Article › peer-review
  35 Scopus citations

• Structure-activity relationships for the induction of differentiation of hl-60 human acute promyelocytic leukemia cells by anthracyclines

  Schwartz, E. L. & Sartorelli, A. C., Jul 1 1982, In: Cancer research. 42, 7, p. 2651-2655 5 p.

  Research output: Contribution to journal › Article › peer-review
  75 Scopus citations

• Structure-activity relationships of the epothilones and the first in vivo comparison with paclitaxel

  Su, D. S., Balog, A., Meng, D., Bertinato, P., Danishefsky, S. J., Zheng, Y. H., Chou, T. C., He, L. & Horwitz, S. B., 1997, In: Angewandte Chemie (International Edition in English). 36, 19, p. 2093-2096 4 p.

  Research output: Contribution to journal › Article › peer-review
  121 Scopus citations

• Structure-activity study of cytotoxicity and microtubule assembly in vitro by taxol and related taxanes

  Parness, J., Kingston, D. G. I., Powell, R. G., Harracksingh, C. & Horwitz, S. B., Apr 14 1982, In: Biochemical and Biophysical Research Communications. 105, 3, p. 1082-1089 8 p.

  Research output: Contribution to journal › Article › peer-review
  122 Scopus citations

• Structure-activity study of the inhibition of microtubule assembly in vitro by podophyllotoxin and its congeners

  Loike, J. D., Brewer, C. F., Sternlicht, H., Gensler, W. J. & Horwitz, S. B., Dec 1 1978, In: Cancer Research. 38, 9, p. 2688-2693 6 p.

  Research output: Contribution to journal › Article › peer-review
  152 Scopus citations

• Structure-Activity Study of the Inhibition of Microtubule Assembly in Vitro by Podophyllotoxin and Its Congeners

  Loike, J. D., Brewer, C. F., Sternlicht, H., Gensler, W. J. & Horwitz, S. B., Sep 1978, In: Cancer research. 38, 9, p. 1-2688 2688 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Structure and biochemical properties of PRL-1, a phosphatase implicated in cell growth, differentiation, and tumor invasion

  Sun, J. P., Wang, W. Q., Yang, H., Liu, S., Liang, F., Fedorov, A. A., Almo, S. C. & Zhang, Z. Y., Sep 13 2005, In: Biochemistry. 44, 36, p. 12009-12021 13 p.

  Research output: Contribution to journal › Article › peer-review
  72 Scopus citations

• Structure and cancer immunotherapy of the B7 family member B7x

  Jeon, H., Vigdorovich, V., Garrett-Thomson, S. C., Janakiram, M., Ramagopal, U. A., Abadi, Y. M., Lee, J. S., Scandiuzzi, L., Ohaegbulam, K. C., Chinai, J. M., Zhao, R., Yao, Y., Mao, Y., Sparano, J. A., Almo, S. C. & Zang, X., 2014, In: Cell Reports. 9, 3, p. 1089-1098 10 p.

  Research output: Contribution to journal › Article › peer-review
  48 Scopus citations

• Structure and catalytic mechanism of LigI: Insight into the amidohydrolase enzymes of cog3618 and lignin degradation

  Hobbs, M. E., Malashkevich, V., Williams, H. J., Xu, C., Sauder, J. M., Burley, S. K., Almo, S. C. & Raushel, F. M., Apr 24 2012, In: Biochemistry. 51, 16, p. 3497-3507 11 p.

  Research output: Contribution to journal › Article › peer-review
  23 Scopus citations

• Structure and characterization of crimean-congo hemorrhagic fever virus GP38

  Mishra, A. K., Moyer, C. L., Abelson, D. M., Deer, D. J., El Omari, K., Duman, R., Lobel, L., Lutwama, J. J., Dye, J. M., Wagner, A., Chandran, K., Cross, R. W., Geisbert, T. W., Zeitlin, L., Bornholdt, Z. A. & McLellan, J. S., Mar 1 2020, In: Journal of virology. 94, 8, e02005-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Scopus citations

• Structure and dynamics of the actin filament

  Guan, J. Q., Takamoto, K., Almo, S. C., Reisler, E. & Chance, M. R., Mar 8 2005, In: Biochemistry. 44, 9, p. 3166-3175 10 p.

  Research output: Contribution to journal › Article › peer-review
  54 Scopus citations

• Structure and dynamics of the kinesin-microtubule interaction revealed by fluorescence polarization microscopy

  Sosa, H., Asenjo, A. B. & Peterman, E. J. G., 2010, In: Methods in cell biology. 95, C, p. 505-519 15 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Structure and enzymic activity of ribonuclease-A esterified at glutamic acid-49 and aspartic acid-53

  Acharya, A. S., Manjula, B. N. & Vithayathil, P. J., 1978, In: Biochemical Journal. 173, 3, p. 821-830 10 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Structure and evolution of a family of interspersed repetitive DNA sequences in Caenorhabditis elegans

  Felsenstein, K. M. & Emmons, S. W., Jul 1 1987, In: Journal of Molecular Evolution. 25, 3, p. 230-240 11 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Structure and expression of a novel, neuronal protein kinase C (PKC1B) from Caenorhabditis elegans. PKC1B is expressed selectively in neurons that receive, transmit, and process environmental signals

  Land, M., Islas-Trejo, A., Freedman, J. H. & Rubin, C. S., 1994, In: Journal of Biological Chemistry. 269, 12, p. 9234-9244 11 p.

  Research output: Contribution to journal › Article › peer-review
  47 Scopus citations

• Structure and expression of murine malic enzyme mRNA. Differentiation-dependent accumulation of two forms of malic enzyme mRNA in 3T3-L1 cells.

  Bagchi, S., Wise, L. S., Brown, M. L., Bregman, D., Sul, H. S. & Rubin, C. S., Feb 5 1987, In: Journal of Biological Chemistry. 262, 4, p. 1558-1565 8 p.

  Research output: Contribution to journal › Article › peer-review
  34 Scopus citations

• Structure and expression of novel spliced leader RNA genes in Caenorhabditis elegans

  Ross, L. H., Freedman, J. H. & Rubin, C. S., 1995, In: Journal of Biological Chemistry. 270, 37, p. 22066-22075 10 p.

  Research output: Contribution to journal › Article › peer-review
  45 Scopus citations

• Structure and expression of the Caenorhabditis elegans protein kinase C2 gene. Origins and regulated expression of a family of Ca²⁺ -activated protein kinase C isoforms

  Islas-Trejo, A., Land, M., Tcherepanova, I., Freedman, J. H. & Rubin, C. S., Mar 7 1997, In: Journal of Biological Chemistry. 272, 10, p. 6629-6640 12 p.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• Structure and expression of two β genes in a β thalassemia homozygote

  Young, K., Margulies, L., Donovan-Peluso, M., Clyne, J., Driscoll, M. C., Dobkin, C., Leibowitz, D., Russo, G., Schiliro, G. & Bank, A., 1985, In: Journal of Molecular and Applied Genetics. 3, 1, p. 1-6 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes

  Kalodimos, C. G., Biris, N., Bonvin, A. M. J. J., Levandoski, M. M., Guennuegues, M., Boelens, R. & Kaptein, R., Jul 16 2004, In: Science. 305, 5682, p. 386-389 4 p.

  Research output: Contribution to journal › Article › peer-review
  416 Scopus citations

• Structure and function in high and low affinity hemoglobins

  Simon, S. R., Friedman, J. M. & Scott, T. W., Jan 1 1985, In: Federation Proceedings. 44, 5, p. No. 8008

  Research output: Contribution to journal › Article › peer-review

• Structure and function of neonatal social communication in a genetic mouse model of autism

  Takahashi, T., Okabe, S., Broin, P., Nishi, A., Ye, K., Beckert, M. V., Izumi, T., Machida, A., Kang, G., Abe, S., Pena, J. L., Golden, A., Kikusui, T. & Hiroi, N., Sep 1 2016, In: Molecular Psychiatry. 21, 9, p. 1208-1214 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  48 Scopus citations

• Structure and function of small ribonucleoproteins from eukaryotic cells.

  Steitz, J. A., Berg, C., Gottlieb, E., Hardin, J. A., Hashimoto, C., Hendrick, J. P., Hinterberger, M., Krikeles, M., Lerner, M. R. & Mount, S. M., 1982, In: Princess Takamatsu symposia. 12, p. 101-107 7 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Structure and function of the CD1 family of MHC-like cell surface proteins

  Blumberg, R. S., Gerdes, D., Chott, A., Porcelli, S. A. & Balk, S. P., Dec 1 1995, In: Immunological Reviews. 147, p. X-29

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Structure and Function of the CD1 Family of MHC‐like Cell Surface Proteins

  Blumberg, R. S., Gerdes, D., Chott, A., Porcelli, S. A. & Balk, S. P., Oct 1995, In: Immunological Reviews. 147, 1, p. 5-29 25 p.

  Research output: Contribution to journal › Article › peer-review
  87 Scopus citations

• Structure and function of the human calcium-sensing receptor: Insights from natural and engineered mutations and allosteric modulators: Ca2+-Sensing Receptor Review Series

  Hu, J. & Spiegel, A. M., Sep 2007, In: Journal of Cellular and Molecular Medicine. 11, 5, p. 908-922 15 p.

  Research output: Contribution to journal › Article › peer-review
  100 Scopus citations

• Structure and function of the mammalian egg zona pellucida

  Wassarman, P., Chen, J., Cohen, N., Litscher, E., Liu, C., Qi, H. & Williams, Z., Oct 15 1999, In: Journal of Experimental Zoology. 285, 3, p. 251-258 8 p.

  Research output: Contribution to journal › Article › peer-review
  67 Scopus citations

• Structure and function of the somatosensory system: A neurotoxicological perspective

  Arezzo, J. C., Schaumburg, H. H. & Spencer, P. S., 1982, In: Environmental health perspectives. Vol. 44, p. 23-30 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Scopus citations

• Structure and function of the virulence-associated high-temperature requirement A of Mycobacterium tuberculosis

  MohamedMohaideen, N. N., Palaninathan, S. K., Morin, P. M., Williams, B. J., Braunstein, M., Tichy, S. E., Locker, J., Russell, D. H., Jacobs, W. R. & Sacchettini, J. C., Jun 10 2008, In: Biochemistry. 47, 23, p. 6092-6102 11 p.

  Research output: Contribution to journal › Article › peer-review
  49 Scopus citations

• Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae

  Singh, V., Shi, W., Almo, S. C., Evans, G. B., Furneaux, R. H., Tyler, P. C., Painter, G. F., Lenz, D. H., Mee, S., Zheng, R. & Schramm, V. L., Oct 31 2006, In: Biochemistry. 45, 43, p. 12929-12941 13 p.

  Research output: Contribution to journal › Article › peer-review
  57 Scopus citations

• Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity

  Wallace, B. D., Roberts, A. B., Pollet, R. M., Ingle, J. D., Biernat, K. A., Pellock, S. J., Venkatesh, M. K., Guthrie, L., O'Neal, S. K., Robinson, S. J., Dollinger, M., Figueroa, E., McShane, S. R., Cohen, R. D., Jin, J., Frye, S. V., Zamboni, W. C., Pepe-Ranney, C., Mani, S., Kelly, L. & 1 others, Redinbo, M. R., Sep 17 2015, In: Chemistry and Biology. 22, 9, p. 1238-1249 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  137 Scopus citations

• Structure and ligand selection of hemoglobin II from Lucina pectinata

  Gavira, J. A., Camara-Artigas, A., De Jesús-Bonilla, W., López-Garriga, J., Lewis, A., Pietri, R., Yeh, S. R., Cadilla, C. L. & García-Ruiz, J. M., Apr 4 2008, In: Journal of Biological Chemistry. 283, 14, p. 9414-9423 10 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• Structure and mechanism of a pentameric formate channel

  Waight, A. B., Love, J. & Wang, D. N., Jan 2010, In: Nature Structural and Molecular Biology. 17, 1, p. 31-38 8 p.

  Research output: Contribution to journal › Article › peer-review
  72 Scopus citations

• Structure and pathology of myelin (author's transl)

  Hirano, A., Dec 1 1979, In: Clinical Neurology. 19, 12, p. 809-817 9 p.

  Research output: Contribution to journal › Article › peer-review

• Structure and reactivity in hemoglobin: implications of recent picosecond transient raman and absorption studies

  Friedman, J. M., Ondrias, M. R., Findsen, E. W. & Simon, S. R., Apr 3 1985, In: Proceedings of SPIE - The International Society for Optical Engineering. 533, p. 8-14 7 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations