• 3788 Citations
  • 31 h-Index
19952020

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Article

ACE gene D/D genotype as a risk factor for chronic nephrotoxicity from calcineurin inhibitors in liver transplant recipients

Gallon, L., Akalin, E., Lynch, P., Rothberg, L., Parker, M., Schiano, T., Abecassis, M. & Murphy, B., Feb 1 2006, In : Transplantation. 81, 3, p. 463-468 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection

Kaminski, M. M., Alcantar, M. A., Lape, I. T., Greensmith, R., Huske, A. C., Valeri, J. A., Marty, F. M., Klämbt, V., Azzi, J., Akalin, E., Riella, L. V. & Collins, J. J., Jun 1 2020, In : Nature Biomedical Engineering. 4, 6, p. 601-609 9 p.

Research output: Contribution to journalArticle

Addition of plasmapheresis decreases the incidence of acute antibody-mediated rejection in sensitized patients with strong donor-specific antibodies

Akalin, E., Dinavahi, R., Friedlander, R., Ames, S., de Boccardo, G., Sehgal, V., Schröppel, B., Bhaskaran, M., Lerner, S., Fotino, M., Murphy, B. & Bromberg, J. S., Jul 1 2008, In : Clinical Journal of the American Society of Nephrology. 3, 4, p. 1160-1167 8 p.

Research output: Contribution to journalArticle

70 Scopus citations

A large, international study on post-transplant glomerular diseases: The TANGO project

Uffing, A., Pérez-Sáez, M. J., La Manna, G., Comai, G., Fischman, C., Farouk, S., Manfro, R. C., Bauer, A. C., Lichtenfels, B., Mansur, J. B., Tedesco-Silva, H., Kirsztajn, G. M., Manonelles, A., Bestard, O., Riella, M. C., Hokazono, S. R., Arias-Cabrales, C., David-Neto, E., Ventura, C. G., Akalin, E. & 8 others, Mohammed, O., Khankin, E. V., Safa, K., Malvezzi, P., O'Shaughnessy, M. M., Cheng, X. S., Cravedi, P. & Riella, L. V., Sep 12 2018, In : BMC Nephrology. 19, 1, 229.

Research output: Contribution to journalArticle

6 Scopus citations

A multicenter, prospective study of C2-monitored cyclosporine microemulsion in a U.S. population of de novo renal transplant recipients

Vincenti, F., Mendez, R., Curtis, J., Light, J., Pearson, T., Wu, Y. M., Katz, S. M., Akalin, E., Esterl, R., Gugliuzza, K., Shihab, F., Jordan, S., Jonsson, J., Molmenti, E. & Barbeito, R., Oct 15 2005, In : Transplantation. 80, 7, p. 910-916 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Antibodies reactive to Non-HLA antigens in transplant glomerulopathy

Dinavahi, R., George, A., Tretin, A., Akalin, E., Ames, S., Bromberg, J. S., DeBoccardo, G., DiPaola, N., Lerner, S. M., Mehrotra, A., Murphy, B. T., Nadasdy, T., Paz-Artal, E., Salomon, D. R., Schröppel, B., Sehgal, V., Sachidanandam, R. & Heeger, P. S., Jun 1 2011, In : Journal of the American Society of Nephrology. 22, 6, p. 1168-1178 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Antibody-Mediated Rejection

Akalin, E. & Watschinger, B., Jul 1 2007, In : Seminars in Nephrology. 27, 4, p. 393-407 15 p.

Research output: Contribution to journalArticle

19 Scopus citations

A pathogenesis-based transcript signature in donor-specific antibody-positive kidney transplant patients with normal biopsies

Broin, P. O., Hayde, N., Bao, Y., Ye, B., Calder, B., de Boccardo, G., Lubetzky, M., Ajaimy, M., Pullman, J., Colovai, A., Akalin, E. & Golden, A. A. J., Jan 1 2014, In : Genomics Data. 2, p. 357-360 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Banff 2019 Meeting Report: Molecular diagnostics in solid organ transplantation-Consensus for the Banff Human Organ Transplant (B-HOT) gene panel and open source multicenter validation

Mengel, M., Loupy, A., Haas, M., Roufosse, C., Naesens, M., Akalin, E., Clahsen-van Groningen, M. C., Dagobert, J., Demetris, A. J., Duong van Huyen, J. P., Gueguen, J., Issa, F., Robin, B., Rosales, I., Von der Thüsen, J. H., Sanchez-Fueyo, A., Smith, R. N., Wood, K., Adam, B. & Colvin, R. B., 2020, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalArticle

Open Access

Binding of activated protein c to a specific receptor on human mononuclear phagocytes inhibits intracellular calcium signaling and monocyte-dependent proliferative responses

Hancock, W. W., Grey, S. T., Hau, L., Akalin, E., Orthner, C., Sayegh, M. H. & Salem, H. H., Dec 27 1995, In : Transplantation. 60, 12, p. 1525-1532 8 p.

Research output: Contribution to journalArticle

116 Scopus citations

Blocking cell microtubule assembly inhibits the alloimmune response in vitro and prolongs renal allograft survival by inhibition of Th1 and sparing of Th2 cell function in vivo

Akalin, E., Hancock, W. W., Perico, N., Remuzzi, G., Imberti, O., Carpenter, C. B. & Sayegh, M. H., Jan 1 1995, In : Journal of the American Society of Nephrology. 5, 7, p. 1418-1425 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Campath induction in HCV and HCV/HIV-seropositive kidney transplant recipients

Vivanco, M., Friedmann, P., Xia, Y., Klair, T., Marfo, K., De Boccardo, G., Greenstein, S., Chapochnick-Friedmann, J., Kinkhabwala, M., Ajaimy, M., Lubetzky, M. L., Akalin, E. & Kayler, L. K., Oct 1 2013, In : Transplant International. 26, 10, p. 1016-1026 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

CD28-B7 blockade after alloantigenic challenge in vivo inhibits thl cytokines but spares Th2

Sayegh, M. H., Akalin, E., Hancock, W. W., Russell, M. E., Carpenter, C. B., Linsley, P. S. & Turka, L. A., May 1 1995, In : Journal of Experimental Medicine. 181, 5, p. 1869-1874 6 p.

Research output: Contribution to journalArticle

Open Access
499 Scopus citations

CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system

Khoury, S. J., Akalin, E., Chandraker, A., Turka, L. A., Linsley, P. S., Sayegh, M. H. & Hancock, W. W., Jan 1 1995, In : Journal of Immunology. 155, 10, p. 4521-4524 4 p.

Research output: Contribution to journalArticle

186 Scopus citations

CD28-B7 T cell costimulatory blockade by CTLA4Ig in the rat renal allograft model: Inhibition of cell-mediated and humoral immune responses in vivo

Akalin, E., Chandraker, A., Russell, M. E., Turka, L. A., Hancock, W. W. & Sayegh, M. H., Dec 27 1996, In : Transplantation. 62, 12, p. 1942-1945 4 p.

Research output: Contribution to journalArticle

59 Scopus citations

Chronic cardiac rejection in the LEW to F344 rat model: Blockade of CD28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis

Russell, M. E., Hancock, W. W., Akalin, E., Wallace, A. F., Glysing-Jensen, T., Willett, T. A. & Sayegh, M. H., Feb 1 1996, In : Journal of Clinical Investigation. 97, 3, p. 833-838 6 p.

Research output: Contribution to journalArticle

Open Access
156 Scopus citations

Chronic organizing microangiopathy in a renal transplant recipient

Wyatt, C. M., Dikman, S., Sehgal, V., Murphy, B. T., Bromberg, J. S., Ames, S. & Akalin, E., Aug 1 2005, In : Nephrology Dialysis Transplantation. 20, 8, p. 1734-1737 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clinical, Histological, and Molecular Markers Associated With Allograft Loss in Transplant Glomerulopathy Patients

Kamal, L., Broin, P., Bao, Y., Ajaimy, M., Lubetzky, M., Gupta, A., de Boccardo, G., Pullman, J. M., Golden, A. & Akalin, E., Sep 1 2015, In : Transplantation. 99, 9, p. 1912-1918 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
8 Scopus citations

Clinical and molecular significance of microvascular inflammation in transplant kidney biopsies

Gupta, A., Broin, P., Bao, Y., Pullman, J., Kamal, L., Ajaimy, M., Lubetzky, M., Colovai, A., Schwartz, D., De Boccardo, G., Golden, A. & Akalin, E., Jan 1 2016, In : Kidney international. 89, 1, p. 217-225 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Clinical outcomes after conversion from brand-name tacrolimus (Prograf) to a generic formulation in renal transplant recipients: A retrospective cohort study

Marfo, K., Aitken, S. & Akalin, E., Aug 1 2013, In : P and T. 38, 8, p. 484-488 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Colchicine Interferes with L-Selectin and Leukocyte Function-Associated Antigen-1 Expression on Human T Lymphocytes and Inhibits T Cell Activation

Perico, N., Ostermann, D., Bontempelli, M., Morigi, M., Amuchastegui, C. S., Zoja, C., Akalin, E., Sayegh, M. H. & Remuzzi, G., Apr 1996, In : Journal of the American Society of Nephrology. 7, 4, p. 594-601 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Cytomegalovirus disease in high-risk transplant recipients despite ganciclovir or valganciclovir prophylaxis

Akalin, E., Sehgal, V., Ames, S., Hossain, S., Daly, L., Barbara, M. & Bromberg, J. S., Jun 1 2003, In : American Journal of Transplantation. 3, 6, p. 731-735 5 p.

Research output: Contribution to journalArticle

121 Scopus citations

Deceased-donor acute kidney injury is not associated with kidney allograft failure

Hall, I. E., Akalin, E., Bromberg, J. S., Doshi, M. D., Greene, T., Harhay, M. N., Jia, Y., Mansour, S. G., Mohan, S., Muthukumar, T., Reese, P. P., Schröppel, B., Singh, P., Thiessen-Philbrook, H. R., Weng, F. L. & Parikh, C. R., Jan 2019, In : Kidney international. 95, 1, p. 199-209 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Desensitization protocols and their outcome

Marfo, K., Lu, A., Ling, M. & Akalin, E., Apr 1 2011, In : Clinical Journal of the American Society of Nephrology. 6, 4, p. 922-936 15 p.

Research output: Contribution to journalArticle

144 Scopus citations

Differential expression of profibrotic and growth factors in chronic allograft nephropathy

Hotchkiss, H., Chu, T. H. T., Hancock, W. W., Schröppel, B., Kretzler, M., Schmid, H., Liu, Y., Dikman, S. & Akalin, E., Feb 2006, In : Transplantation. 81, 3, p. 342-349 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

Differential outcomes in 3 types of acute antibody-mediated rejection

Rafiq, M. A., de Boccardo, G., Schröppel, B., Bromberg, J. S., Sehgal, V., Dinavahi, R., Murphy, B. & Akalin, E., Jan 1 2009, In : Clinical Transplantation. 23, 6, p. 951-957 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Effect of high-dose intravenous immunoglobulin on anti-HLA antibodies in sensitized kidney transplant candidates

Nair, V., Sawinski, D., Akalin, E., Friedlander, R., Ebcioglu, Z., Sehgal, V., Dinavahi, R., Khaim, R., Ames, S., Lerner, S., Murphy, B., Bromberg, J. S., Heeger, P. S. & Schröppel, B., May 1 2012, In : Clinical Transplantation. 26, 3, p. E261-E268

Research output: Contribution to journalArticle

17 Scopus citations

Effects of DNA Methylation on Progression to Interstitial Fibrosis and Tubular Atrophy in Renal Allograft Biopsies: A Multi-Omics Approach

Bontha, S. V., Maluf, D. G., Archer, K. J., Dumur, C. I., Dozmorov, M. G., King, A. L., Akalin, E., Mueller, T. F., Gallon, L. & Mas, V. R., 2017, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalArticle

6 Scopus citations

Efficacy of levofloxacin in the treatment of BK viremia: A multicenter, double-blinded, randomized, placebo-controlled trial

Lee, B. T., Gabardi, S., Grafals, M., Hofmann, R. M., Akalin, E., Aljanabi, A., Mandelbrot, D. A., Adey, D. B., Heher, E., Fan, P. Y., Conte, S., Dyer-Ward, C. & Chandraker, A., Mar 7 2014, In : Clinical Journal of the American Society of Nephrology. 9, 3, p. 583-589 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Emphysematous cystitis and pyelitis in a diabetic renal transplant recipient

Akalin, E., Hyde, C., Schmitt, G., Kaufman, J. & Hamburger, R. J., Oct 15 1996, In : Transplantation. 62, 7, p. 1024-1026 3 p.

Research output: Contribution to journalArticle

34 Scopus citations

Factors associated with failure to list hiv-positive kidney transplant candidates

Sawinski, D., Wyatt, C. M., Casagrande, L., Myoung, P., Bijan, I., Akalin, E., Schröppel, B., Deboccardo, G., Sehgal, V., Dinavahi, R., Lerner, S., Ames, S., Bromberg, J., Huprikar, S., Keller, M. & Murphy, B., Jun 1 2009, In : American Journal of Transplantation. 9, 6, p. 1467-1471 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Gene expression analysis in human renal allograft biopsy samples using high-density oligoarray technology

Akalin, E., Hendrix, R. C., Giri Polavarapu, R., Pearson, T. C., Neylan, J. F., Larsen, C. P. & Lakkis, F. G., Sep 15 2001, In : Transplantation. 72, 5, p. 948-953 6 p.

Research output: Contribution to journalArticle

97 Scopus citations

Gene therapy and solid-organ transplantation

Akalin, E. & Bromberg, J. S., Jan 1 2002, In : Kidney international. 61, SUPPL. 1, p. S56-S60

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Genomics of BK viremia in kidney transplant recipients

Lubetzky, M., Bao, Y., Ó Broin, P., Marfo, K., Ajaimy, M., Aljanabi, A., De Boccardo, G., Golden, A. & Akalin, E., Feb 27 2014, In : Transplantation. 97, 4, p. 451-456 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Genomics of chronic allograft injury

Akalin, E. & O'Connell, P. J., Dec 1 2010, In : Kidney international. 78, SUPPL. 119, p. S33-S37

Research output: Contribution to journalArticle

14 Scopus citations

Glomerular infiltration by CXCR3+ ICOS+ activated T cells in chronic allograft nephropathy with transplant glomerulopathy

Akalin, E., Dikman, S., Murphy, B., Bromberg, J. S. & Hancock, W. W., Sep 1 2003, In : American Journal of Transplantation. 3, 9, p. 1116-1120 5 p.

Research output: Contribution to journalArticle

68 Scopus citations

Hospital readmissions in diabetic kidney transplant recipients with peripheral vascular disease

Lubetzky, M., Kamal, L., Ajaimy, M., Akalin, E. & Kayler, L., Jun 1 2018, In : Clinical Transplantation. 32, 6, e13271.

Research output: Contribution to journalArticle

1 Scopus citations

Hyperuricemia is associated with the development of the composite outcomes of new cardiovascular events and chronic allograft nephropathy

Akalin, E., Ganeshan, S. V., Winston, J. & Muntner, P., Sep 15 2008, In : Transplantation. 86, 5, p. 652-658 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Improving pancreas graft utilization through importation

Torabi, J., Rocca, J. P., Choinski, K., Lorenzen, K., Yongue, C., Lubetzsky, M. L., Herbert, M. E., Chokechanachaisakul, A., Ajaimy, M., Kamal, L., Akalin, E., Kinkhabwala, M. & Graham, J. A., Jan 1 2018, In : Clinical Transplantation. 32, 1, e13154.

Research output: Contribution to journalArticle

Increased access to transplantation of highly sensitized patients under the new kidney allocation system. A single center experience

Colovai, A. I., Ajaimy, M., Kamal, L. G., Masiakos, P., Chan, S., Savchik, C., Lubetzky, M., de Boccardo, G., Courson, A., Chokechanachaisakul, A., Graham, J. A., Greenstein, S. M., Kinkhabwala, M., Rocca, J. P. & Akalin, E., Oct 20 2016, (Accepted/In press) In : Human Immunology.

Research output: Contribution to journalArticle

8 Scopus citations

Increased intragraft rejection-associated gene transcripts in patients with donor-specific antibodies and normal biopsies

Hayde, N., Broin, P. Ó., Bao, Y., De Boccardo, G., Lubetzky, M., Ajaimy, M., Pullman, J., Colovai, A., Golden, A. A. J. & Akalin, E., Sep 2014, In : Kidney international. 86, 3, p. 600-609 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Induction of "Infectious" Tolerance to MHC-Incompatible Cardiac Allografts in CD4 Monoclonal Antibody-Treated Sensitized Rat Recipients

Onodera, K., Lehmann, M., Akalin, E., Volk, H. D., Sayegh, M. H. & Kupiec-Weglinski, J. W., Sep 1 1996, In : Journal of Immunology. 157, 5, p. 1944-1950 7 p.

Research output: Contribution to journalArticle

111 Scopus citations

Inhibition of the alloimmune response with synthetic nonpolymorphic class II MHC peptides

Murphy, B., Akalin, E., Watschinger, B., Carpenter, C. B. & Sayegh, M. H., Jan 1 1995, In : Transplantation Proceedings. 27, 1, p. 409-410 2 p.

Research output: Contribution to journalArticle

13 Scopus citations
2 Scopus citations

Intrathymic tolerance in the Lewis-to-F344 chronic cardiac allograft rejection model

Shin, Y. T., Adams, D. H., Wyner, L. R., Akalin, E., Sayegh, M. H. & Karnovsky, M. J., Jun 27 1995, In : Transplantation. 59, 12, p. 1647-1653 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Intravenous immunoglobulin and thymoglobulin facilitate kidney transplantation in complement-dependent cytotoxicity B-cell and flow cytometry T- or B-cell crossmatch-positive patients

Akalin, E., Ames, S., Sehgal, V., Fotino, M., Daly, L., Murphy, B. & Bromberg, J. S., Nov 27 2003, In : Transplantation. 76, 10, p. 1444-1447 4 p.

Research output: Contribution to journalArticle

51 Scopus citations

Intravenous immunoglobulin induction treatment in flow cytometry cross-match - Positive kidney transplant recipients

Akalin, E. & Bromberg, J. S., Apr 2005, In : Human Immunology. 66, 4, p. 359-363 5 p.

Research output: Contribution to journalArticle

31 Scopus citations