White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living with and without HIV

Carrie D. Johnston, Donald R. Hoover, Qiuhu Shi, Anjali Sharma, David B. Hanna, Kathryn Anastos, Phyllis C. Tien, Margaret Fischl, Deborah Gustafson, Amanda Spence, Roksana Karim, Audrey French, Michael Schneider, Adaora A. Adimora, Caitlin Moran, Deborah Konkle-Parker, Marshall J. Glesby

Research output: Contribution to journalArticle

Abstract

Diabetes mellitus (DM) is associated with expansion of proinflammatory lymphocyte subsets. We investigated the relationship of total white blood cell (WBC) count and lymphocyte subsets with incident DM in the Women's Interagency HIV Study (WIHS). Higher CD4 and CD8 T cell counts, lymphocyte count, and total WBC count were associated with incident DM among both women with and without HIV, although the association of CD8 was not statistically significant among women without HIV.

Original languageEnglish (US)
Pages (from-to)131-133
Number of pages3
JournalAIDS Research and Human Retroviruses
Volume36
Issue number2
DOIs
StatePublished - Feb 2020

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Keywords

  • CD4
  • CD8
  • HIV-1
  • diabetes mellitus
  • lymphocyte
  • white blood cell
  • women

ASJC Scopus subject areas

  • Immunology
  • Virology
  • Infectious Diseases

Cite this

Johnston, C. D., Hoover, D. R., Shi, Q., Sharma, A., Hanna, D. B., Anastos, K., Tien, P. C., Fischl, M., Gustafson, D., Spence, A., Karim, R., French, A., Schneider, M., Adimora, A. A., Moran, C., Konkle-Parker, D., & Glesby, M. J. (2020). White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living with and without HIV. AIDS Research and Human Retroviruses, 36(2), 131-133. https://doi.org/10.1089/aid.2019.0174