White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living with and without HIV

Carrie D. Johnston; Donald R. Hoover; Qiuhu Shi; Anjali Sharma; David B. Hanna; Kathryn Anastos; Phyllis C. Tien; Margaret Fischl; Deborah Gustafson; Amanda Spence; Roksana Karim; Audrey French; Michael Schneider; Adaora A. Adimora; Caitlin Moran; Deborah Konkle-Parker; Marshall J. Glesby

doi:10.1089/aid.2019.0174

White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living with and without HIV

Carrie D. Johnston, Donald R. Hoover, Qiuhu Shi, Anjali Sharma, David B. Hanna, Kathryn Anastos, Phyllis C. Tien, Margaret Fischl, Deborah Gustafson, Amanda Spence, Roksana Karim, Audrey French, Michael Schneider, Adaora A. Adimora, Caitlin Moran, Deborah Konkle-Parker, Marshall J. Glesby

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Diabetes mellitus (DM) is associated with expansion of proinflammatory lymphocyte subsets. We investigated the relationship of total white blood cell (WBC) count and lymphocyte subsets with incident DM in the Women's Interagency HIV Study (WIHS). Higher CD4 and CD8 T cell counts, lymphocyte count, and total WBC count were associated with incident DM among both women with and without HIV, although the association of CD8 was not statistically significant among women without HIV.

Original language	English (US)
Pages (from-to)	131-133
Number of pages	3
Journal	AIDS Research and Human Retroviruses
Volume	36
Issue number	2
DOIs	https://doi.org/10.1089/aid.2019.0174
State	Published - Feb 2020

Keywords

CD4
CD8
HIV-1
diabetes mellitus
lymphocyte
white blood cell
women

ASJC Scopus subject areas

Infectious Diseases
Virology
Immunology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1089/aid.2019.0174

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Johnston, C. D., Hoover, D. R., Shi, Q., Sharma, A., Hanna, D. B., Anastos, K., Tien, P. C., Fischl, M., Gustafson, D., Spence, A., Karim, R., French, A., Schneider, M., Adimora, A. A., Moran, C., Konkle-Parker, D., & Glesby, M. J. (2020). White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living with and without HIV. AIDS Research and Human Retroviruses, 36(2), 131-133. https://doi.org/10.1089/aid.2019.0174

Johnston, CD, Hoover, DR, Shi, Q, Sharma, A , Hanna, DB , Anastos, K, Tien, PC, Fischl, M, Gustafson, D, Spence, A, Karim, R, French, A, Schneider, M, Adimora, AA, Moran, C, Konkle-Parker, D & Glesby, MJ 2020, 'White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living with and without HIV', AIDS Research and Human Retroviruses, vol. 36, no. 2, pp. 131-133. https://doi.org/10.1089/aid.2019.0174

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abstract = "Diabetes mellitus (DM) is associated with expansion of proinflammatory lymphocyte subsets. We investigated the relationship of total white blood cell (WBC) count and lymphocyte subsets with incident DM in the Women's Interagency HIV Study (WIHS). Higher CD4 and CD8 T cell counts, lymphocyte count, and total WBC count were associated with incident DM among both women with and without HIV, although the association of CD8 was not statistically significant among women without HIV.",

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AU - Anastos, Kathryn

AU - Tien, Phyllis C.

AU - Fischl, Margaret

AU - Gustafson, Deborah

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AU - Karim, Roksana

AU - French, Audrey

AU - Schneider, Michael

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AU - Glesby, Marshall J.

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AB - Diabetes mellitus (DM) is associated with expansion of proinflammatory lymphocyte subsets. We investigated the relationship of total white blood cell (WBC) count and lymphocyte subsets with incident DM in the Women's Interagency HIV Study (WIHS). Higher CD4 and CD8 T cell counts, lymphocyte count, and total WBC count were associated with incident DM among both women with and without HIV, although the association of CD8 was not statistically significant among women without HIV.

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White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living with and without HIV

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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