@article{f27563e0b5b64a6f80cf74b0ed9d494b,
title = "White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living with and without HIV",
abstract = "Diabetes mellitus (DM) is associated with expansion of proinflammatory lymphocyte subsets. We investigated the relationship of total white blood cell (WBC) count and lymphocyte subsets with incident DM in the Women's Interagency HIV Study (WIHS). Higher CD4 and CD8 T cell counts, lymphocyte count, and total WBC count were associated with incident DM among both women with and without HIV, although the association of CD8 was not statistically significant among women without HIV.",
keywords = "CD4, CD8, HIV-1, diabetes mellitus, lymphocyte, white blood cell, women",
author = "Johnston, {Carrie D.} and Hoover, {Donald R.} and Qiuhu Shi and Anjali Sharma and Hanna, {David B.} and Kathryn Anastos and Tien, {Phyllis C.} and Margaret Fischl and Deborah Gustafson and Amanda Spence and Roksana Karim and Audrey French and Michael Schneider and Adimora, {Adaora A.} and Caitlin Moran and Deborah Konkle-Parker and Glesby, {Marshall J.}",
note = "Funding Information: National Institutes of Health grants NIH/NIAID T32 AI007613, NIH institutes support the WIHS cohort, U01-AI-103401, U01-AI-103408, U01-AI-035004, U01-AI-031834, U01-AI-034993, U01-AI-034994, U01-AI-103397, U01-AI-103390, U01-AI-034989, U01-AI-042590, U01-HD-032632, K01-HL-137557. WIHS data collection is also supported by UL1-TR000004 (UCSF CTSA), UL1-TR000454 (Atlanta CTSA), P30-AI-050410 (UNC CFAR), and P30-AI-027767 (UAB CFAR). Funding Information: Data in this article were collected by the Women{\textquoteright}s Interagency HIV Study (WIHS). WIHS (Principal Investigators): UAB-MS WIHS (Mirjam-Colette Kempf and D.K.-P.), U01-AI-103401; Atlanta WIHS (Ighovwerha Ofotokun, Anandi Sheth, and Gina Wingood), U01-AI-103408; Bronx WIHS (K.A. and A.S.), U01-AI-035004; Brooklyn WIHS (D.G. and Tracey Wilson), U01-AI-031834; Chicago WIHS (Mardge Cohen and A.F.), U01-AI-034993; Metropolitan Washington WIHS (Seble Kassaye and Daniel Merenstein), U01-AI-034994; Miami WIHS (Maria Alcaide, M.F., and Deborah Jones), U01-AI-103397; UNC WIHS (A.A.A.), U01-AI-103390; Connie Wofsy Women{\textquoteright}s HIV Study, Northern California (Bradley Aouizerat and P.C.T.), U01-AI-034989; WIHS Data Management and Analysis Center (Stephen Gange and Elizabeth Golub), U01-AI-042590; Southern California WIHS ( Joel Milam), U01-HD-032632 (WIHS I— WIHS IV). K01-HL-137557 (D.B.H.). The WIHS is funded primarily by the National Institute of Allergy and Infectious Diseases (NIAID), with additional co-funding from the Eu-nice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Cancer Institute (NCI), the National Institute on Drug Abuse (NIDA), and the National Institute on Mental Health (NIMH). Targeted supplemental funding for specific projects is also provided by the National Institute of Dental and Craniofacial Research (NIDCR), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute on Deafness and other Communication Disorders (NIDCD), and the NIH Office of Research on Women{\textquoteright}s Health. Funding Information: Drs. A.S. and M.J.G. receive research funding from Gilead, not related to this article. Dr. P.C.T. receives research funding from Merck, prior research support from Theratechnologies in the past 36 months. Dr. A.A.A. received personal funding from Gilead, Merck, and Viiv for consultation and participation in advisory boards. No other authors have commercial or other associations that might pose a conflict of interest. Publisher Copyright: {\textcopyright} Copyright 2020, Mary Ann Liebert, Inc.",
year = "2020",
month = feb,
doi = "10.1089/aid.2019.0174",
language = "English (US)",
volume = "36",
pages = "131--133",
journal = "AIDS Research and Human Retroviruses",
issn = "0889-2229",
publisher = "Mary Ann Liebert Inc.",
number = "2",
}
