Wetherbee ail. Documentation of a neurological disease in a Vermont family 90 years later

J. M. Powers, D. S. Horoupian, H. H. Schaumburg

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A 35 year old woman began to experience weakness in the left leg one year before her terminal admission. One month before admission she developed dyspnea which steadily worsened and she was admitted because of severe ventilatory insufficiency secondary to muscle weakness. The patient died on the second hospital day. The neuropathologic findings consisted of neuronal loss in the anterior horns and dorsal nuclei of Clarke, neuronal intracytoplasmic inclusions and posterior and lateral column demyelination. This report supports the role of familial amyotrophic lateral sclerosis as a link between common motor neuron disease and classical spinocerebellar degeneration.

Original languageEnglish (US)
Pages (from-to)139-140
Number of pages2
JournalCanadian Journal of Neurological Sciences
Volume1
Issue number2
StatePublished - 1974

Fingerprint

Documentation
Spinocerebellar Degenerations
Motor Neuron Disease
Muscle Weakness
Demyelinating Diseases
Dyspnea
Leg
Spinal Cord Dorsal Horn
Amyotrophic lateral sclerosis 1

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Wetherbee ail. Documentation of a neurological disease in a Vermont family 90 years later. / Powers, J. M.; Horoupian, D. S.; Schaumburg, H. H.

In: Canadian Journal of Neurological Sciences, Vol. 1, No. 2, 1974, p. 139-140.

Research output: Contribution to journalArticle

Powers, J. M. ; Horoupian, D. S. ; Schaumburg, H. H. / Wetherbee ail. Documentation of a neurological disease in a Vermont family 90 years later. In: Canadian Journal of Neurological Sciences. 1974 ; Vol. 1, No. 2. pp. 139-140.
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