Watery Diarrhea in a Patient with Myasthenia Gravis, Thymoma, and Immunodeficiency

Sanjeev Gupta, S. H. Saverymuttu, J. S.R. Gibbs, D. J. Evans, H. J.F. Hodgson

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

An elderly man with thymoma, myasthenia gravis, and hypogammaglobulincmia developed profuse watery diarrhea. Infusions of γ‐globulin caused the diarrhea to resolve. The patient succumbed to fulminant bronchopneumonia. At necropsy he was found to have widespread cytomegalovirus infection with duodenal and ileal ulceration, subtotal villous atrophy, marked nonspecific inflammation of the small intestine and bronchopneumonia. In addition Herpes simplex infection and invasive candidiasis were present. Patients with immunodeficiency are susceptible to a variety of gastrointestinal pathogens, particularly viral.

Original languageEnglish (US)
Pages (from-to)877-881
Number of pages5
JournalThe American Journal of Gastroenterology
Volume80
Issue number11
DOIs
StatePublished - Nov 1985
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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