Watery diarrhea in a patient with myasthenia gravis, thymoma, and immunodeficiency

Sanjeev Gupta, S. H. Saverymuttu, J. S R Gibbs, D. J. Evans, H. J. Hodgson

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

An elderly man with thymoma, myasthenia gravis, and hypogammaglobulinemia developed profuse watery diarrhea. Infusions of γ-globulin caused the diarrhea to resolve. The patient succumbed to fulminant bronchopneumonia. At necropsy he was found to have widespread cytomegalovirus infection with duodenal and ileal ulceration, subtotal villous atrophy, marked nonspecific inflammation of the small intestine and bronchopneumonia. In addition Herpes simplex infection and invasive candidiasis were present. Patients with immunodeficiency are susceptible to a variety of gastrointestinal pathogens, particularly viral.

Original languageEnglish (US)
Pages (from-to)877-881
Number of pages5
JournalAmerican Journal of Gastroenterology
Volume80
Issue number11
StatePublished - 1985
Externally publishedYes

Fingerprint

Bronchopneumonia
Thymoma
Myasthenia Gravis
Diarrhea
Invasive Candidiasis
Agammaglobulinemia
Herpes Simplex
Globulins
Cytomegalovirus Infections
Small Intestine
Atrophy
Inflammation
Infection

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Gupta, S., Saverymuttu, S. H., Gibbs, J. S. R., Evans, D. J., & Hodgson, H. J. (1985). Watery diarrhea in a patient with myasthenia gravis, thymoma, and immunodeficiency. American Journal of Gastroenterology, 80(11), 877-881.

Watery diarrhea in a patient with myasthenia gravis, thymoma, and immunodeficiency. / Gupta, Sanjeev; Saverymuttu, S. H.; Gibbs, J. S R; Evans, D. J.; Hodgson, H. J.

In: American Journal of Gastroenterology, Vol. 80, No. 11, 1985, p. 877-881.

Research output: Contribution to journalArticle

Gupta, S, Saverymuttu, SH, Gibbs, JSR, Evans, DJ & Hodgson, HJ 1985, 'Watery diarrhea in a patient with myasthenia gravis, thymoma, and immunodeficiency', American Journal of Gastroenterology, vol. 80, no. 11, pp. 877-881.
Gupta, Sanjeev ; Saverymuttu, S. H. ; Gibbs, J. S R ; Evans, D. J. ; Hodgson, H. J. / Watery diarrhea in a patient with myasthenia gravis, thymoma, and immunodeficiency. In: American Journal of Gastroenterology. 1985 ; Vol. 80, No. 11. pp. 877-881.
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