Watching single protons bind

Research output: Contribution to journalArticle

Abstract

Using single-molecule biophysical studies in an ion channel, the protonation state of engineered basic amino acids was measured in real time, making it possible to calculate the pKas of the substituted residues and creating a unique, comprehensive dataset for theorists studying the effects of an electrostatic environment on integral membrane protein function.

Original languageEnglish (US)
Pages (from-to)128-130
Number of pages3
JournalNature Chemical Biology
Volume2
Issue number3
DOIs
StatePublished - Mar 2006

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Basic Amino Acids
Static Electricity
Ion Channels
Protons
Membrane Proteins
Datasets

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Watching single protons bind. / Akabas, Myles.

In: Nature Chemical Biology, Vol. 2, No. 3, 03.2006, p. 128-130.

Research output: Contribution to journalArticle

Akabas, Myles. / Watching single protons bind. In: Nature Chemical Biology. 2006 ; Vol. 2, No. 3. pp. 128-130.
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