Warfarin Pharmacology, Clinical Management, and Evaluation of Hemorrhagic Risk for the Elderly

Laurie G. Jacobs

Research output: Contribution to journalReview article

48 Scopus citations

Abstract

Warfarin, a vitamin K antagonist, is currently the most extensively used oral anticoagulant world-wide. It is prescribed for a variety of indications and has undergone extensive clinical study. Still, despite wide usage and considerable accumulated data from clinical trials demonstrating efficacy for a variety of thrombotic and thromboembolic conditions, warfarin is underutilized because its management is complex for both patients and physicians. However, despite these limitations, warfarin can be managed with relative safety, even in an elderly population.

Original languageEnglish (US)
Pages (from-to)157-167
Number of pages11
JournalCardiology clinics
Volume26
Issue number2
DOIs
StatePublished - May 1 2008

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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