TY - JOUR
T1 - Vulnerable Plaque
T2 - A Review of Current Concepts in Pathophysiology and Imaging
AU - Khan, Mohammed Hasan
AU - Rochlani, Yogita
AU - Yandrapalli, Srikanth
AU - Aronow, Wilbert S.
AU - Frishman, William H.
N1 - Publisher Copyright:
©2018 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Advances in our understanding of the natural history and biology of atherosclerotic vascular disease led to the concept of a vulnerable plaque (VP), which is predisposed toward more rapid progression and acute coronary events. With newer technologies, we now have at our disposal high-quality imaging studies, both invasive and noninvasive, which promise in identifying plaque characteristics that make it more vulnerable. Upcoming trials aim to evaluate the utility of imaging VP in predicting clinical events. We discuss the role of VP imaging in managing atherosclerotic vascular disease.
AB - Advances in our understanding of the natural history and biology of atherosclerotic vascular disease led to the concept of a vulnerable plaque (VP), which is predisposed toward more rapid progression and acute coronary events. With newer technologies, we now have at our disposal high-quality imaging studies, both invasive and noninvasive, which promise in identifying plaque characteristics that make it more vulnerable. Upcoming trials aim to evaluate the utility of imaging VP in predicting clinical events. We discuss the role of VP imaging in managing atherosclerotic vascular disease.
KW - intravascular ultrasound
KW - near infra-red spectroscopy
KW - optical coherence tomography
KW - thin-cap fibroatheroma
KW - vulnerable plaque
UR - http://www.scopus.com/inward/record.url?scp=85076008998&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85076008998&partnerID=8YFLogxK
U2 - 10.1097/CRD.0000000000000238
DO - 10.1097/CRD.0000000000000238
M3 - Review article
C2 - 30489331
AN - SCOPUS:85076008998
SN - 1061-5377
VL - 28
SP - 3
EP - 9
JO - Cardiology in review
JF - Cardiology in review
IS - 1
ER -