Vitamin D and pulmonary function in obese asthmatic children

Laura A. Lautenbacher; Sunit P. Jariwala; Morri E. Markowitz; Deepa Rastogi

doi:10.1002/ppul.23485

Vitamin D and pulmonary function in obese asthmatic children

Laura A. Lautenbacher, Sunit P. Jariwala, Morri E. Markowitz, Deepa Rastogi

Research output: Contribution to journal › Article

10 Scopus citations

Abstract

Objective: Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of co-existent obesity and vitamin D deficiency on pulmonary function is poorly understood. Methods: We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children's hospital. Serum cytokines associated with Th1 and Th2 inflammation and 25-hydroxyvitamin D (25-OHD) were quantified in fasting serum. 25-OHD levels ≥30ng/ml were categorized as sufficient,

Original language	English (US)
Journal	Pediatric Pulmonology
DOIs	https://doi.org/10.1002/ppul.23485
State	Accepted/In press - 2016

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Keywords

Asthma
Obesity
Pulmonary function testing
Vitamin D deficiency

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Pulmonary and Respiratory Medicine

Cite this

Lautenbacher, L. A., Jariwala, S. P., Markowitz, M. E., & Rastogi, D. (Accepted/In press). Vitamin D and pulmonary function in obese asthmatic children. Pediatric Pulmonology. https://doi.org/10.1002/ppul.23485

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AU - Lautenbacher, Laura A.

AU - Jariwala, Sunit P.

AU - Markowitz, Morri E.

AU - Rastogi, Deepa

PY - 2016

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N2 - Objective: Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of co-existent obesity and vitamin D deficiency on pulmonary function is poorly understood. Methods: We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children's hospital. Serum cytokines associated with Th1 and Th2 inflammation and 25-hydroxyvitamin D (25-OHD) were quantified in fasting serum. 25-OHD levels ≥30ng/ml were categorized as sufficient,

AB - Objective: Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of co-existent obesity and vitamin D deficiency on pulmonary function is poorly understood. Methods: We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children's hospital. Serum cytokines associated with Th1 and Th2 inflammation and 25-hydroxyvitamin D (25-OHD) were quantified in fasting serum. 25-OHD levels ≥30ng/ml were categorized as sufficient,

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Access to Document

10.1002/ppul.23485