Vitamin D and pulmonary function in obese asthmatic children

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Abstract

Objective: Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of co-existent obesity and vitamin D deficiency on pulmonary function is poorly understood. Methods: We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children's hospital. Serum cytokines associated with Th1 and Th2 inflammation and 25-hydroxyvitamin D (25-OHD) were quantified in fasting serum. 25-OHD levels ≥30ng/ml were categorized as sufficient,

Original languageEnglish (US)
JournalPediatric Pulmonology
DOIs
StateAccepted/In press - 2016

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Keywords

  • Asthma
  • Obesity
  • Pulmonary function testing
  • Vitamin D deficiency

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

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