Vitamin D and pulmonary function in obese asthmatic children

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective: Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of co-existent obesity and vitamin D deficiency on pulmonary function is poorly understood. Methods: We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children's hospital. Serum cytokines associated with Th1 and Th2 inflammation and 25-hydroxyvitamin D (25-OHD) were quantified in fasting serum. 25-OHD levels ≥30ng/ml were categorized as sufficient,

Original languageEnglish (US)
JournalPediatric Pulmonology
DOIs
StateAccepted/In press - 2016

Fingerprint

Vitamin D
Lung
Vitamin D Deficiency
Asthma
Obesity
Morbidity
Urban Hospitals
Serum
Hispanic Americans
African Americans
Fasting
Cytokines
Inflammation
Weights and Measures

Keywords

  • Asthma
  • Obesity
  • Pulmonary function testing
  • Vitamin D deficiency

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

Cite this

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title = "Vitamin D and pulmonary function in obese asthmatic children",
abstract = "Objective: Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of co-existent obesity and vitamin D deficiency on pulmonary function is poorly understood. Methods: We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children's hospital. Serum cytokines associated with Th1 and Th2 inflammation and 25-hydroxyvitamin D (25-OHD) were quantified in fasting serum. 25-OHD levels ≥30ng/ml were categorized as sufficient,",
keywords = "Asthma, Obesity, Pulmonary function testing, Vitamin D deficiency",
author = "Lautenbacher, {Laura A.} and Jariwala, {Sunit P.} and Markowitz, {Morri E.} and Deepa Rastogi",
year = "2016",
doi = "10.1002/ppul.23485",
language = "English (US)",
journal = "Pediatric Pulmonology",
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TY - JOUR

T1 - Vitamin D and pulmonary function in obese asthmatic children

AU - Lautenbacher, Laura A.

AU - Jariwala, Sunit P.

AU - Markowitz, Morri E.

AU - Rastogi, Deepa

PY - 2016

Y1 - 2016

N2 - Objective: Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of co-existent obesity and vitamin D deficiency on pulmonary function is poorly understood. Methods: We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children's hospital. Serum cytokines associated with Th1 and Th2 inflammation and 25-hydroxyvitamin D (25-OHD) were quantified in fasting serum. 25-OHD levels ≥30ng/ml were categorized as sufficient,

AB - Objective: Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of co-existent obesity and vitamin D deficiency on pulmonary function is poorly understood. Methods: We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children's hospital. Serum cytokines associated with Th1 and Th2 inflammation and 25-hydroxyvitamin D (25-OHD) were quantified in fasting serum. 25-OHD levels ≥30ng/ml were categorized as sufficient,

KW - Asthma

KW - Obesity

KW - Pulmonary function testing

KW - Vitamin D deficiency

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U2 - 10.1002/ppul.23485

DO - 10.1002/ppul.23485

M3 - Article

JO - Pediatric Pulmonology

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