Vitamin D and chronic rhinitis

Waleed M. Abuzeid, Nadeem A. Akbar, Mark A. Zacharek

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

Purpose of review: To discuss the role of vitamin D in chronic rhinitis and chronic rhinosinusitis (CRS). Recent findings: Vitamin D has been shown to have an immunomodulatory effect with a significant impact on immune function. Specifically, vitamin D regulates the mechanisms which suppress the inflammatory response and direct the differentiation fate of immune cells. Vitamin D has been shown to play an important role in asthma, and the concept of the unified airway model allows the extrapolation of vitamin D as a critical player in chronic rhinitis and rhinosinusitis. Summary: Recent findings on the function of vitamin D may explain aspects of the pathophysiology of chronic rhinitis and CRS, and may help direct future treatment of these diseases.

Original languageEnglish (US)
Pages (from-to)13-17
Number of pages5
JournalCurrent Opinion in Allergy and Clinical Immunology
Volume12
Issue number1
DOIs
StatePublished - Feb 1 2012
Externally publishedYes

Keywords

  • Allergic rhinitis
  • Chronic rhinitis
  • Chronic rhinosinusitis
  • Immunomodulation
  • Vitamin D

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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