Visualizing the Histone Code on LSD1

Matthew J. Gamble, W. Lee Kraus

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In this issue, Garcia-Bassets et al. (2007) show that spurious transcriptional activation by unliganded nuclear receptors is inhibited by histone lysine methylation. This inhibitory histone modification code is efficiently countered by the ligand-dependent recruitment of histone lysine demethylases, including lysine-specific demethylase 1 (LSD1), which appear to be used for this purpose by a number of signal-regulated transcriptional activators.

Original languageEnglish (US)
Pages (from-to)433-434
Number of pages2
JournalCell
Volume128
Issue number3
DOIs
StatePublished - Feb 9 2007
Externally publishedYes

Fingerprint

Histone Code
Histones
Lysine
Histone Demethylases
Methylation
Cytoplasmic and Nuclear Receptors
Transcriptional Activation
Chemical activation
Ligands

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Visualizing the Histone Code on LSD1. / Gamble, Matthew J.; Kraus, W. Lee.

In: Cell, Vol. 128, No. 3, 09.02.2007, p. 433-434.

Research output: Contribution to journalArticle

Gamble, Matthew J. ; Kraus, W. Lee. / Visualizing the Histone Code on LSD1. In: Cell. 2007 ; Vol. 128, No. 3. pp. 433-434.
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