Visual loss associated with tacrolimus: Case report and review of the literature

Kapil G. Kapoor; Sarah N. Mirza; John A. Gonzales; Syed K. Gibran

doi:10.3109/15569521003662963

Visual loss associated with tacrolimus: Case report and review of the literature

Kapil G. Kapoor, Sarah N. Mirza, John A. Gonzales, Syed K. Gibran

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Tacrolimus is an immunosuppressive medication in the class of calcineurin inhibitors that acts by inhibiting T-cell and interleukin-2 activity, and is commonly used after allogeneic organ transplant. We present a patient who used tacrolimus after cadaveric kidney transplant and experienced blurry vision. Ocular examination and patient's course subsequently revealed aqueous tear deficiency as a dose-dependent adverse effect of oral tacrolimus.

Original language	English (US)
Pages (from-to)	137-139
Number of pages	3
Journal	Cutaneous and Ocular Toxicology
Volume	29
Issue number	2
DOIs	https://doi.org/10.3109/15569521003662963
State	Published - Jun 2010
Externally published	Yes

Keywords

Aqueous tear deficiency
Dry eyes
FK506
Prograf
Tacrolimus

ASJC Scopus subject areas

Toxicology

Access to Document

10.3109/15569521003662963

Cite this

@article{8e1f52a62f224eaf81888fae60f11e5a,

title = "Visual loss associated with tacrolimus: Case report and review of the literature",

abstract = "Tacrolimus is an immunosuppressive medication in the class of calcineurin inhibitors that acts by inhibiting T-cell and interleukin-2 activity, and is commonly used after allogeneic organ transplant. We present a patient who used tacrolimus after cadaveric kidney transplant and experienced blurry vision. Ocular examination and patient's course subsequently revealed aqueous tear deficiency as a dose-dependent adverse effect of oral tacrolimus.",

keywords = "Aqueous tear deficiency, Dry eyes, FK506, Prograf, Tacrolimus",

author = "Kapoor, {Kapil G.} and Mirza, {Sarah N.} and Gonzales, {John A.} and Gibran, {Syed K.}",

year = "2010",

month = jun,

doi = "10.3109/15569521003662963",

language = "English (US)",

volume = "29",

pages = "137--139",

journal = "Cutaneous and Ocular Toxicology",

issn = "1556-9527",

publisher = "Informa Healthcare",

number = "2",

}

TY - JOUR

T1 - Visual loss associated with tacrolimus

T2 - Case report and review of the literature

AU - Kapoor, Kapil G.

AU - Mirza, Sarah N.

AU - Gonzales, John A.

AU - Gibran, Syed K.

PY - 2010/6

Y1 - 2010/6

N2 - Tacrolimus is an immunosuppressive medication in the class of calcineurin inhibitors that acts by inhibiting T-cell and interleukin-2 activity, and is commonly used after allogeneic organ transplant. We present a patient who used tacrolimus after cadaveric kidney transplant and experienced blurry vision. Ocular examination and patient's course subsequently revealed aqueous tear deficiency as a dose-dependent adverse effect of oral tacrolimus.

AB - Tacrolimus is an immunosuppressive medication in the class of calcineurin inhibitors that acts by inhibiting T-cell and interleukin-2 activity, and is commonly used after allogeneic organ transplant. We present a patient who used tacrolimus after cadaveric kidney transplant and experienced blurry vision. Ocular examination and patient's course subsequently revealed aqueous tear deficiency as a dose-dependent adverse effect of oral tacrolimus.

KW - Aqueous tear deficiency

KW - Dry eyes

KW - FK506

KW - Prograf

KW - Tacrolimus

UR - http://www.scopus.com/inward/record.url?scp=77952177604&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952177604&partnerID=8YFLogxK

U2 - 10.3109/15569521003662963

DO - 10.3109/15569521003662963

M3 - Article

C2 - 20233105

AN - SCOPUS:77952177604

SN - 1556-9527

VL - 29

SP - 137

EP - 139

JO - Cutaneous and Ocular Toxicology

JF - Cutaneous and Ocular Toxicology

IS - 2

ER -

Visual loss associated with tacrolimus: Case report and review of the literature

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this