TY - JOUR
T1 - Venovenous extracorporeal membrane oxygenation for acute respiratory failure
T2 - A clinical review from an international group of experts
AU - Fan, Eddy
AU - Gattinoni, Luciano
AU - Combes, Alain
AU - Schmidt, Matthieu
AU - Peek, Giles
AU - Brodie, Dan
AU - Muller, Thomas
AU - Morelli, Andrea
AU - Ranieri, V. Marco
AU - Pesenti, Antonio
AU - Brochard, Laurent
AU - Hodgson, Carol
AU - Van Kiersbilck, Cecile
AU - Roch, Antoine
AU - Quintel, Michael
AU - Papazian, Laurent
N1 - Publisher Copyright:
© 2016, Springer-Verlag Berlin Heidelberg and ESICM.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Despite expensive life-sustaining interventions delivered in the ICU, mortality and morbidity in patients with acute respiratory failure (ARF) remain unacceptably high. Extracorporeal membrane oxygenation (ECMO) has emerged as a promising intervention that may provide more efficacious supportive care to these patients. Improvements in technology have made ECMO safer and easier to use, allowing for the potential of more widespread application in patients with ARF. A greater appreciation of the complications associated with the placement of an artificial airway and mechanical ventilation has led clinicians and researchers to seek viable alternatives to providing supportive care in these patients. Thus, this review will summarize the current knowledge regarding the use of venovenous (VV)-ECMO for ARF and describe some of the recent controversies in the field, such as mechanical ventilation, anticoagulation and transfusion therapy, and ethical concerns in patients supported with VV-ECMO.
AB - Despite expensive life-sustaining interventions delivered in the ICU, mortality and morbidity in patients with acute respiratory failure (ARF) remain unacceptably high. Extracorporeal membrane oxygenation (ECMO) has emerged as a promising intervention that may provide more efficacious supportive care to these patients. Improvements in technology have made ECMO safer and easier to use, allowing for the potential of more widespread application in patients with ARF. A greater appreciation of the complications associated with the placement of an artificial airway and mechanical ventilation has led clinicians and researchers to seek viable alternatives to providing supportive care in these patients. Thus, this review will summarize the current knowledge regarding the use of venovenous (VV)-ECMO for ARF and describe some of the recent controversies in the field, such as mechanical ventilation, anticoagulation and transfusion therapy, and ethical concerns in patients supported with VV-ECMO.
KW - Critical care
KW - Extracorporeal membrane oxygenation
KW - Intensive care units
KW - Respiratory distress syndrome, adult
KW - Respiratory failure
KW - Review
KW - Ventilation, artificial
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U2 - 10.1007/s00134-016-4314-7
DO - 10.1007/s00134-016-4314-7
M3 - Review article
C2 - 27007108
AN - SCOPUS:84961839095
SN - 0342-4642
VL - 42
SP - 712
EP - 724
JO - Intensive Care Medicine
JF - Intensive Care Medicine
IS - 5
ER -