Vasopressin-induced changes in permeability of peritoneal mesothelium for urea "in vitro".

M. Radkowski, A. Breborowicz, J. Knapowski

Research output: Contribution to journalArticle

Abstract

Vasopressin (ADH) acts in humans mainly upon renal collecting tubules. By changing their water permeability it plays a key role in regulation of renal water excretion. Acting upon vascular smooth muscle cells, it causes vasoconstriction and raised arterial blood pressure. This hormone was also proven to cause constriction of cultured mesangial cels, it causes vasoconstriction and raised arterial blood pressure. This urea (Seldin, Giebisch 1985), to release the natriuretic hormone as well as to stimulate hepatic glycogenolysis (Abramov et al. 1987). The influence of vasopressin upon peritoneal transport of solutes was studied, too. ADH influenced the passage of phosphate and rubidium through the isolated rabbit mesentery (Berndt, Gosselin 1961) as well as sodium flux through isolated rabbit omentum (Shear et al. 1966). It caused the drop in urea dialysance in dogs subjected to peritoneal dialysis (Henderson et al. 1971). The subject of our study was the assessment of the action of the antidiuretic hormone under "in vitro" conditions upon the peritoneal transfer of urea, the solute present in human body fluids and removable by peritoneal dialysis.

Original languageEnglish (US)
Pages (from-to)17-22
Number of pages6
JournalActa Medica Polona
Volume30
Issue number1-2
StatePublished - Dec 1 1989

ASJC Scopus subject areas

  • Medicine(all)

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    Radkowski, M., Breborowicz, A., & Knapowski, J. (1989). Vasopressin-induced changes in permeability of peritoneal mesothelium for urea "in vitro". Acta Medica Polona, 30(1-2), 17-22.