Variability of respiration and sleep during polysomnography in individuals with TBI

William Lu, Joshua Cantor, R. Nisha Aurora, Michael Nguyen, Teresa Ashman, Lisa Spielman, Anne Ambrose, Jason W. Krellman, Wayne Gordon

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

BACKGROUND: Obstructive sleep apnea (OSA) is commonly found in individuals with traumatic brain injury (TBI) and may exacerbate TBI-related symptoms. Nocturnal polysomnography (NPSG) is considered the gold standard for detecting the presence of sleep apnea. However, there is a limitation with its use known as the 'first-night effect' (aberrant polysomnography findings on the first night in a sleep lab). OBJECTIVE: The primary objectives were to investigate the night-to-night consistency of diagnosing and classifying obstructive sleep apnea in individuals with TBI, and ascertain if individuals with TBI are prone to a first-night effect. METHODS: 47 community-dwelling adults with self-reported mild-to-severe TBI underwent two nights of in-laboratory NPSG to examine variability between the first and second night with regards to OSA diagnosis and severity as well as sleep architecture. RESULTS: OSA detection and severity were consistent from night-to-night in 89% of participants with TBI. Participants with TBI demonstrated longer REM latency on the first night compared to the second night of sleep study. CONCLUSIONS: These findings indicate that two nights of in-laboratory NPSG are generally consistent in reliably diagnosing OSA in individuals with TBI and that first-night effects are minimal. One night of NPSG has diagnostic utility in the evaluation of sleep disorders in individuals with TBI.

Original languageEnglish (US)
Pages (from-to)245-251
Number of pages7
JournalNeuroRehabilitation
Volume35
Issue number2
DOIs
StatePublished - Jan 1 2014

Keywords

  • Traumatic brain injury
  • obstructive sleep apnea
  • polysomnography
  • sleep

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation
  • Clinical Neurology

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    Lu, W., Cantor, J., Aurora, R. N., Nguyen, M., Ashman, T., Spielman, L., Ambrose, A., Krellman, J. W., & Gordon, W. (2014). Variability of respiration and sleep during polysomnography in individuals with TBI. NeuroRehabilitation, 35(2), 245-251. https://doi.org/10.3233/NRE-141117