Value of Preoperative Renal Artery Embolization in Reducing Blood Transfusion Requirements during Nephrectomy for Renal Cell Carcinoma

Curtis W. Bakal, Jacob Cynamon, Philip S. Lakritz, Seymour Sprayregen

Research output: Contribution to journalArticle

73 Scopus citations

Abstract

The authors evaluated the effectiveness of preoperative ethanol renal artery embolization in reducing transfusion requirements during nephrectomy for renal cell carcinoma. Of 93 consecutive patients who underwent nephrectomy for renal cell carcinoma from 1980 to 1990, 24 patients underwent embolization within 24 hours of nephrectomy. Finding in this group were compared with those in 69 control patients who underwent surgery without preoperative embolization. Embolized tumors were larger than nonembolized ones (mean volume, 595 vs 257 mL) (P < .05). Patients with large hypervascular tumors (volume over 250 mL) who underwent complete embolization received significantly smaller mean blood transfusion volumes than control patients (250 vs 800 mL; P = .01). The transfusion volume associated with incomplete embolization was higher than that associated with no embolization. Complete alcohol embolization significantly reduces the volume of blood transfused during nephrectomy for large hypervascular renal cell carcinomas, and incomplete embolization is associated with larger transfusions. Preoperative embolization must be complete and should be performed more widely.

Original languageEnglish (US)
Pages (from-to)727-731
Number of pages5
JournalJournal of Vascular and Interventional Radiology
Volume4
Issue number6
DOIs
StatePublished - Jan 1 1993
Externally publishedYes

Keywords

  • Kidney neoplasms, therapy, 81.324, 81.451, 81.458
  • Kidney, surgery, 81.451, 81.458
  • RAE
  • Renal arteries, therapeutic blockade, 961.1264
  • renal artery embolization

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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