Validity of family history data on severe headache and migraine

Ruth Ottman, Susan Hong, Richard B. Lipton

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

This study evaluated the validity of family history data on severe headache and migraine obtained from adult probands with epilepsy in a family study of seizure disorders. We compared the probands' reports of severe headaches and migraines in their parents and full siblings with symptom-based diagnoses based on self-reports. Overall sensitivity was 48% for severe headache and 44% for migraine. When we used reports of severe headaches to screen for migraine headaches in the relatives, sensitivity was 56%. These results indicate that severe headache and migraine are underreported in family history interviews with first-degree relatives. To obtain accurate information on headaches in families for clinical practice and genetic research, direct interviews with each relative may be required.

Original languageEnglish (US)
Pages (from-to)1954-1960
Number of pages7
JournalNeurology
Volume43
Issue number10
StatePublished - Oct 1993
Externally publishedYes

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Migraine Disorders
Headache
Epilepsy
Interviews
Genetic Research
Family Practice
Self Report
Siblings
Parents

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Validity of family history data on severe headache and migraine. / Ottman, Ruth; Hong, Susan; Lipton, Richard B.

In: Neurology, Vol. 43, No. 10, 10.1993, p. 1954-1960.

Research output: Contribution to journalArticle

Ottman, R, Hong, S & Lipton, RB 1993, 'Validity of family history data on severe headache and migraine', Neurology, vol. 43, no. 10, pp. 1954-1960.
Ottman, Ruth ; Hong, Susan ; Lipton, Richard B. / Validity of family history data on severe headache and migraine. In: Neurology. 1993 ; Vol. 43, No. 10. pp. 1954-1960.
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