Abstract
This study evaluated the validity of family history data on severe headache and migraine obtained from adult probands with epilepsy in a family study of seizure disorders. We compared the probands' reports of severe headaches and migraines in their parents and full siblings with symptom-based diagnoses based on self-reports. Overall sensitivity was 48% for severe headache and 44% for migraine. When we used reports of severe headaches to screen for migraine headaches in the relatives, sensitivity was 56%. These results indicate that severe headache and migraine are underreported in family history interviews with first-degree relatives. To obtain accurate information on headaches in families for clinical practice and genetic research, direct interviews with each relative may be required.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1954-1960 |
| Number of pages | 7 |
| Journal | Neurology |
| Volume | 43 |
| Issue number | 10 |
| State | Published - Oct 1993 |
ASJC Scopus subject areas
- Clinical Neurology