Validation study of a new transit time ultrasonic flow probe for continuous great vessel measurements

David A. Dean, Chao Xiang Jia, Santos E. Cabreriza, David A. D' Alessandro, Marc L. Dickstein, Michael J. Sardo, Natalya Chalik, Henry M. Spotnitz

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Continuous measurement of cardiac output is important during experimental and clinical cardiac surgery as an indicator of ventricular function. Previous flow probes underestimated flow secondary to position and flow (S-series probes; Transonic Systems, Inc., Ithaca, NY), required frequent calibrations (electromagnetic), and were cumbersome to use. The new A-series probe (ASP) by Transonic Systems, Inc., uses a new X method of ultrasonic illumination insensitive to perturbations in flow. The ASPs were found to be accurate during in vitro studies, but have not been validated in vivo. Six anesthetized pigs were instrumented for right atrium to left atrium bypass, and ASPs were placed on the ascending aorta and pulmonary artery. Baseline measurements included aortic (Ao) and pulmonic flow (P), and thermodilution (Td) cardiac output. Animals then were placed on right heart bypass, and flow was randomly varied from 1 to 6 L/min, and Ao flow was recorded. In addition, ASPs were rotated and their direction reversed. After data collection, the occlusive roller pump (RP) was calibrated using a timed collection method. Calibrated RP flows were plotted versus ASP flows, and regression was applied. There was no difference between mean Ao, P, and Td cardiac outputs at baseline. In addition, changes in position and direction of the probe did not affect measurement of flow. The ASPs showed a highly linear correlation with RP ([r = 0.98, p < 0.01] ASP[L/min] = 0.98 RP- 0.032). During laminar flow states, ASPs are accurate and insensitive to position on the great vessels.

Original languageEnglish (US)
JournalASAIO Journal
Volume42
Issue number5
StatePublished - Sep 1996
Externally publishedYes

Fingerprint

Validation Studies
Ultrasonics
Cardiac Output
Thermodilution
Heart Atria
Right Heart Bypass
Pumps
Ventricular Function
Electromagnetic Phenomena
Lighting
Pulmonary Artery
Calibration
Thoracic Surgery
Aorta
Swine
Lung
Secondary flow
Laminar flow
Surgery
Animals

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering

Cite this

Dean, D. A., Jia, C. X., Cabreriza, S. E., D' Alessandro, D. A., Dickstein, M. L., Sardo, M. J., ... Spotnitz, H. M. (1996). Validation study of a new transit time ultrasonic flow probe for continuous great vessel measurements. ASAIO Journal, 42(5).

Validation study of a new transit time ultrasonic flow probe for continuous great vessel measurements. / Dean, David A.; Jia, Chao Xiang; Cabreriza, Santos E.; D' Alessandro, David A.; Dickstein, Marc L.; Sardo, Michael J.; Chalik, Natalya; Spotnitz, Henry M.

In: ASAIO Journal, Vol. 42, No. 5, 09.1996.

Research output: Contribution to journalArticle

Dean, DA, Jia, CX, Cabreriza, SE, D' Alessandro, DA, Dickstein, ML, Sardo, MJ, Chalik, N & Spotnitz, HM 1996, 'Validation study of a new transit time ultrasonic flow probe for continuous great vessel measurements', ASAIO Journal, vol. 42, no. 5.
Dean DA, Jia CX, Cabreriza SE, D' Alessandro DA, Dickstein ML, Sardo MJ et al. Validation study of a new transit time ultrasonic flow probe for continuous great vessel measurements. ASAIO Journal. 1996 Sep;42(5).
Dean, David A. ; Jia, Chao Xiang ; Cabreriza, Santos E. ; D' Alessandro, David A. ; Dickstein, Marc L. ; Sardo, Michael J. ; Chalik, Natalya ; Spotnitz, Henry M. / Validation study of a new transit time ultrasonic flow probe for continuous great vessel measurements. In: ASAIO Journal. 1996 ; Vol. 42, No. 5.
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