Validation of a Rheumatoid Arthritis Health-Related Quality of Life Instrument, the CSHQ-RA

S. M. Russak, C. D. Sherbourne, D. P. Lubeck, H. D. Paulus, C. F. Chiou, N. Sengupta, J. Borenstein, J. Ofman, Alyson B. Moadel-Robblee, M. H. Weisman

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective. To test the validity and reliability of a newly developed disease-specific multidimensional quality of life instrument: the Cedars-Sinai Health-Related Quality of Life Instrument (CSHQ-RA). Methods. A total of 350 rheumatoid arthritis (RA) patients were asked to complete the CSHQ-RA at 2 time points (4 weeks apart). Patients also completed the Medical Outcomes Study Short Form 36 (SF-36) and the Stanford Health Assessment Questionnaire (HAQ) Disability Index (DI) at the second time point. Construct validity was tested, using Pearson's correlations, by comparing subscale scores on the CSHQ-RA to those obtained from the mental component summary (MCS) and physical component summary (PCS) of the SF-36. HAQ DI scores were used to assess the discriminant validity of the CSHQ-RA. Intraclass correlation coefficients (ICCs) were used to assess test-retest reliability. Results. Response rates for the first and second survey were 83% (291) and 93% (276), respectively; 84% of respondents were women, and mean age was 57 years. Mean scores ± SDs on instruments were: HAQ 0.73 ± 0.69; MCS 49 ± 12; and PCS 33 ± 11. Pearson's correlations between the CSHQ-RA subscale scores and the SF-36 scores ranged from 0.55 to 0.76 (P < 0.001). Analysis of variance indicate that scores on the CSHQ-RA discriminated between levels of physical disability as measured by the HAQ (P < 0.001). Test-retest reliability was demonstrated in the instrument's subscale scores (ICC 0.70-0.90). Conclusion. These results support the construct validity, discriminant validity, and reliability of the CSHQ-RA as a measure that captures the impact of RA on patients' health-related quality of life.

Original languageEnglish (US)
Pages (from-to)798-803
Number of pages6
JournalArthritis Care and Research
Volume49
Issue number6
StatePublished - Dec 15 2003

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Rheumatoid Arthritis
Quality of Life
Reproducibility of Results
Health
Surveys and Questionnaires
Analysis of Variance
Outcome Assessment (Health Care)

Keywords

  • Assessment tool
  • Quality of life
  • Rheumatoid arthritis
  • Validation

ASJC Scopus subject areas

  • Rheumatology

Cite this

Russak, S. M., Sherbourne, C. D., Lubeck, D. P., Paulus, H. D., Chiou, C. F., Sengupta, N., ... Weisman, M. H. (2003). Validation of a Rheumatoid Arthritis Health-Related Quality of Life Instrument, the CSHQ-RA. Arthritis Care and Research, 49(6), 798-803.

Validation of a Rheumatoid Arthritis Health-Related Quality of Life Instrument, the CSHQ-RA. / Russak, S. M.; Sherbourne, C. D.; Lubeck, D. P.; Paulus, H. D.; Chiou, C. F.; Sengupta, N.; Borenstein, J.; Ofman, J.; Moadel-Robblee, Alyson B.; Weisman, M. H.

In: Arthritis Care and Research, Vol. 49, No. 6, 15.12.2003, p. 798-803.

Research output: Contribution to journalArticle

Russak, SM, Sherbourne, CD, Lubeck, DP, Paulus, HD, Chiou, CF, Sengupta, N, Borenstein, J, Ofman, J, Moadel-Robblee, AB & Weisman, MH 2003, 'Validation of a Rheumatoid Arthritis Health-Related Quality of Life Instrument, the CSHQ-RA', Arthritis Care and Research, vol. 49, no. 6, pp. 798-803.
Russak SM, Sherbourne CD, Lubeck DP, Paulus HD, Chiou CF, Sengupta N et al. Validation of a Rheumatoid Arthritis Health-Related Quality of Life Instrument, the CSHQ-RA. Arthritis Care and Research. 2003 Dec 15;49(6):798-803.
Russak, S. M. ; Sherbourne, C. D. ; Lubeck, D. P. ; Paulus, H. D. ; Chiou, C. F. ; Sengupta, N. ; Borenstein, J. ; Ofman, J. ; Moadel-Robblee, Alyson B. ; Weisman, M. H. / Validation of a Rheumatoid Arthritis Health-Related Quality of Life Instrument, the CSHQ-RA. In: Arthritis Care and Research. 2003 ; Vol. 49, No. 6. pp. 798-803.
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abstract = "Objective. To test the validity and reliability of a newly developed disease-specific multidimensional quality of life instrument: the Cedars-Sinai Health-Related Quality of Life Instrument (CSHQ-RA). Methods. A total of 350 rheumatoid arthritis (RA) patients were asked to complete the CSHQ-RA at 2 time points (4 weeks apart). Patients also completed the Medical Outcomes Study Short Form 36 (SF-36) and the Stanford Health Assessment Questionnaire (HAQ) Disability Index (DI) at the second time point. Construct validity was tested, using Pearson's correlations, by comparing subscale scores on the CSHQ-RA to those obtained from the mental component summary (MCS) and physical component summary (PCS) of the SF-36. HAQ DI scores were used to assess the discriminant validity of the CSHQ-RA. Intraclass correlation coefficients (ICCs) were used to assess test-retest reliability. Results. Response rates for the first and second survey were 83{\%} (291) and 93{\%} (276), respectively; 84{\%} of respondents were women, and mean age was 57 years. Mean scores ± SDs on instruments were: HAQ 0.73 ± 0.69; MCS 49 ± 12; and PCS 33 ± 11. Pearson's correlations between the CSHQ-RA subscale scores and the SF-36 scores ranged from 0.55 to 0.76 (P < 0.001). Analysis of variance indicate that scores on the CSHQ-RA discriminated between levels of physical disability as measured by the HAQ (P < 0.001). Test-retest reliability was demonstrated in the instrument's subscale scores (ICC 0.70-0.90). Conclusion. These results support the construct validity, discriminant validity, and reliability of the CSHQ-RA as a measure that captures the impact of RA on patients' health-related quality of life.",
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AU - Sherbourne, C. D.

AU - Lubeck, D. P.

AU - Paulus, H. D.

AU - Chiou, C. F.

AU - Sengupta, N.

AU - Borenstein, J.

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AU - Weisman, M. H.

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N2 - Objective. To test the validity and reliability of a newly developed disease-specific multidimensional quality of life instrument: the Cedars-Sinai Health-Related Quality of Life Instrument (CSHQ-RA). Methods. A total of 350 rheumatoid arthritis (RA) patients were asked to complete the CSHQ-RA at 2 time points (4 weeks apart). Patients also completed the Medical Outcomes Study Short Form 36 (SF-36) and the Stanford Health Assessment Questionnaire (HAQ) Disability Index (DI) at the second time point. Construct validity was tested, using Pearson's correlations, by comparing subscale scores on the CSHQ-RA to those obtained from the mental component summary (MCS) and physical component summary (PCS) of the SF-36. HAQ DI scores were used to assess the discriminant validity of the CSHQ-RA. Intraclass correlation coefficients (ICCs) were used to assess test-retest reliability. Results. Response rates for the first and second survey were 83% (291) and 93% (276), respectively; 84% of respondents were women, and mean age was 57 years. Mean scores ± SDs on instruments were: HAQ 0.73 ± 0.69; MCS 49 ± 12; and PCS 33 ± 11. Pearson's correlations between the CSHQ-RA subscale scores and the SF-36 scores ranged from 0.55 to 0.76 (P < 0.001). Analysis of variance indicate that scores on the CSHQ-RA discriminated between levels of physical disability as measured by the HAQ (P < 0.001). Test-retest reliability was demonstrated in the instrument's subscale scores (ICC 0.70-0.90). Conclusion. These results support the construct validity, discriminant validity, and reliability of the CSHQ-RA as a measure that captures the impact of RA on patients' health-related quality of life.

AB - Objective. To test the validity and reliability of a newly developed disease-specific multidimensional quality of life instrument: the Cedars-Sinai Health-Related Quality of Life Instrument (CSHQ-RA). Methods. A total of 350 rheumatoid arthritis (RA) patients were asked to complete the CSHQ-RA at 2 time points (4 weeks apart). Patients also completed the Medical Outcomes Study Short Form 36 (SF-36) and the Stanford Health Assessment Questionnaire (HAQ) Disability Index (DI) at the second time point. Construct validity was tested, using Pearson's correlations, by comparing subscale scores on the CSHQ-RA to those obtained from the mental component summary (MCS) and physical component summary (PCS) of the SF-36. HAQ DI scores were used to assess the discriminant validity of the CSHQ-RA. Intraclass correlation coefficients (ICCs) were used to assess test-retest reliability. Results. Response rates for the first and second survey were 83% (291) and 93% (276), respectively; 84% of respondents were women, and mean age was 57 years. Mean scores ± SDs on instruments were: HAQ 0.73 ± 0.69; MCS 49 ± 12; and PCS 33 ± 11. Pearson's correlations between the CSHQ-RA subscale scores and the SF-36 scores ranged from 0.55 to 0.76 (P < 0.001). Analysis of variance indicate that scores on the CSHQ-RA discriminated between levels of physical disability as measured by the HAQ (P < 0.001). Test-retest reliability was demonstrated in the instrument's subscale scores (ICC 0.70-0.90). Conclusion. These results support the construct validity, discriminant validity, and reliability of the CSHQ-RA as a measure that captures the impact of RA on patients' health-related quality of life.

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