@article{61af58a1c08242b9b45ffb39d111c443,
title = "UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells",
abstract = "Background: We have previously identified potent novel antimalarial compounds with an unknown mode of action. Results: A photo-reactive affinity capture method was used to identify parasite proteins that interact with these antimalarials. Conclusion: ACT-213615 interacts with Plasmodium falciparum multidrug resistance protein 1 (PfMDR1). Significance: This photo-reactive affinity capture method can be generally used to identify drug targets in live cells.",
author = "Ralf Brunner and Ng, {Caroline L.} and Hamed Aissaoui and Akabas, {Myles H.} and Christoph Boss and Reto Brun and Callaghan, {Paul S.} and Olivier Corminboeuf and Fidock, {David A.} and Frame, {Ithiel J.} and Bibia Heidmann and Bihan, {Am{\'e}lie Le} and Paul Jen{\"o} and Corinna Mattheis and Suzette Moes and M{\"u}ller, {Ingrid B.} and Michelle Paguio and Roepe, {Paul D.} and Romain Siegrist and Till Voss and Welford, {Richard W.D.} and Sergio Wittlin and Christoph Binkert",
year = "2013",
month = aug,
day = "2",
doi = "10.1074/jbc.M113.453159",
language = "English (US)",
volume = "288",
pages = "22576--22583",
journal = "Journal of Biological Chemistry",
issn = "0021-9258",
publisher = "American Society for Biochemistry and Molecular Biology Inc.",
number = "31",
}