We report the use of voriconazole troughs to achieve appropriate therapeutic levels in treatment of a cutaneous Scedosporium apiospermum infection. Following heart transplantation, a 63-year-old immunocompromised patient presented with post-traumatic nodular lesions on his right shin. Pathology showed fungal yeasts with culture revealing Scedosporium apiospermum. According to therapeutic drug monitoring, initial voriconazole treatment was subtherapeutic requiring increased dosing until appropriate therapeutic trough levels were attained, and resolution of the fungal infection was achieved.
|Original language||English (US)|
|Number of pages||3|
|Journal||Medical Mycology Case Reports|
|State||Published - Dec 2018|
- Cutaneous Scedosporium apiospermum
ASJC Scopus subject areas
- Infectious Diseases