Utilization of defibrillators and resynchronization therapy at the time of evaluation at a heart failure and cardiac transplantation center

Daniel B. Sims, Luis I. Garcia, Andrea Mignatti, Paolo C. Colombo, Margaret Jones, Nir Uriel, Donna M. Mancini, Ulrich P. Jorde

Research output: Contribution to journalArticle

7 Scopus citations


Background: Internal cardioverter defibrillators (ICDs) and cardiac resynchronization therapy (CRT) reduce mortality, but are underutilized in routine clinical practice. The use of these devices in patients at the time of an initial evaluation at an advanced heart failure and cardiac transplantation center is unknown. Methods: We retrospectively analyzed consecutive patients who were enrolled in a database examining parameters of cardiopulmonary exercise testing in chronic heart failure (CHF) patients at the time of an initial outpatient evaluation at a tertiary care center. Rates of ICD and CRT use in eligible patients were determined. Results: Two hundred two patients had an average age of 54 ± 13 years and an average peak oxygen consumption (pVO2) of 12.5 ± 4.5 mL/kg/min. Of 97 patients eligible for an ICD only, 57% had an ICD at the time of evaluation. Sixty-four percent of ICD-eligible male patients had an ICD compared to 36% of ICD-eligible female patients (P = 0.015). Of 105 patients meeting criteria for CRT, 54% had a CRT device. There was no difference between CRT use in eligible male and female patients. Conclusions: ICDs and CRT are underutilized in patients with severe CHF at the time of evaluation at a tertiary care center despite young age, objective functional limitation, and active consideration for advanced CHF therapies. Female patients have lower rates of ICD use than male patients.

Original languageEnglish (US)
Pages (from-to)988-993
Number of pages6
JournalPACE - Pacing and Clinical Electrophysiology
Issue number8
StatePublished - Aug 1 2010
Externally publishedYes



  • advanced heart failure
  • cardiac resynchronization therapy
  • defibrillator

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this