Use of pragmatic and explanatory trial designs in acute care research: lessons from COVID-19

Jonathan D. Casey, Laura M. Beskow, Jeremy Brown, Samuel M. Brown, Étienne Gayat, Michelle Ng Gong, Michael O. Harhay, Samir Jaber, Jacob C. Jentzer, Pierre François Laterre, John C. Marshall, Michael A. Matthay, Todd W. Rice, Yves Rosenberg, Alison E. Turnbull, Lorraine B. Ware, Wesley H. Self, Alexandre Mebazaa, Sean P. Collins