Use of ethotoin in phenytoin-related hypersensitivity reactions

Alan B. Ettinger, Solomon L. Moshé, Mark J. Sinnett, Juan C. Canton, Shlomo Shinnar

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Hypersensitivity reactions to phenytoin (PHT) usually result in abandoning the use of hydantoin compounds in the treatment of epilepsy. We report two cases of patients experiencing allergic reactions to PHT who were successfully switched to a related phenylhydantoin, ethotoin, and who remained free of hypersensitivity reactions. Potential mechanisms for differences in hypersensitivity are discussed.

Original languageEnglish (US)
Pages (from-to)29-31
Number of pages3
JournalJournal of Epilepsy
Volume6
Issue number1
DOIs
StatePublished - 1993

Keywords

  • Anticonvulsants
  • Ethotoin
  • Hypersensitivity
  • Phenylhydantoin

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Use of ethotoin in phenytoin-related hypersensitivity reactions'. Together they form a unique fingerprint.

  • Cite this