We studied, retrospectively, the incidence of upper tract urothelial tumors following the treatment of primary transitional cell carcinoma of the bladder in 638 patients. Subsequent tumor development was found in 20 patients (3.1 %) with a mean latency interval between initial treatment of the bladder cancer and diagnosis of the upper urinary tract tumor of eighty months. We did not find a significant difference among treatment modalities on the incidence of upper tract occurrences. Other than carcinoma in situ, tumor stage was not an independent predictive variable.
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