Update in lung cancer 2014

Avrum Spira, Balazs Halmos, Charles A. Powell

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


In the past 2 years, lung cancer research and clinical care have advanced significantly. Advancements in the field have improved outcomes and promise to lead to further reductions in deaths from lung cancer, the leading cause of cancer death worldwide. These advances include identification of new molecular targets for personalized targeted therapy, validation of molecular signatures of lung cancer risk in smokers, progress in lung tumor immunotherapy, and implementation of population-based lung cancer screening with chest computed tomography in the United States. In this review, we highlight recent research in these areas and challenges for the future.

Original languageEnglish (US)
Pages (from-to)283-294
Number of pages12
JournalAmerican journal of respiratory and critical care medicine
Issue number3
StatePublished - Aug 1 2015
Externally publishedYes


  • Biomarkers
  • Chest computed tomography screening
  • Lung cancer
  • Lung immunotherapy
  • Targeted therapy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine


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