Unraveling the Molecular Pathways That Regulate Early Telencephalon Development

Research output: Chapter in Book/Report/Conference proceedingChapter

19 Scopus citations

Abstract

The telencephalon, at the rostral end of the developing central nervous system, starts off as a sheet of neuroepithelial cells. During development, this sheet of cells becomes patterned and morphologically partitioned into areas that give rise to the adult cerebral hemispheres. How does this happen? How are telencephalic precursor cells instructed to generate myriad neural cell types in different areas and at different times as well as to change their rates of cell proliferation, differentiation, and death? The molecular pathways required for patterning the telencephalic neuroepithelium and forming the cerebral hemispheres are beginning to be unraveled.

Original languageEnglish (US)
Title of host publicationNeural Development
EditorsGerald Schatten
Pages17-37
Number of pages21
DOIs
StatePublished - Dec 1 2005

Publication series

NameCurrent Topics in Developmental Biology
Volume69
ISSN (Print)0070-2153

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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    Hébert, J. M. (2005). Unraveling the Molecular Pathways That Regulate Early Telencephalon Development. In G. Schatten (Ed.), Neural Development (pp. 17-37). (Current Topics in Developmental Biology; Vol. 69). https://doi.org/10.1016/S0070-2153(05)69002-3