Unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled HIV infection

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Abstract

Cryptococcal meningoencephalitis (CM) classically occurs in individuals with advanced HIV infection, solid organ transplants, or other immunocompromising conditions. We report a case of fatal CM in a 78-year-old woman with well-controlled HIV infection who had delayed diagnosis, persistently elevated intracranial pressure and pleocytosis of the cerebrospinal fluid. Initial suspicion for CM was low due to her relatively high CD4+ T cell counts, which likely contributed to greater inflammation.

Original languageEnglish (US)
Pages (from-to)14-16
Number of pages3
JournalMedical Mycology Case Reports
Volume32
DOIs
StatePublished - Jun 2021

Keywords

  • Cryptococcal meningoencephalitis
  • Cryptococcosis
  • HIV infection
  • Host immunity
  • Inflammatory response

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

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