Understanding the cortex of crawling cells: insights from Dictyostelium

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18 Scopus citations


All animal cells are believed to use the same basic molecular mechanisms for locomotion when crawling on a surface. Study of a wide range of crawling cells has tended to confirm this belief but has also led to a diversity of hypotheses for locomotion and a bewildering list of candidate effector proteins. The emergence of a powerful model system, Dictyostelium discoideum, for the study of crawling of cells makes definitive tests of hypotheses for locomotion a reality.

Original languageEnglish (US)
Pages (from-to)371-376
Number of pages6
JournalTrends in Cell Biology
Issue number11
StatePublished - Nov 1993

ASJC Scopus subject areas

  • Cell Biology


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