TY - JOUR
T1 - Understanding the cortex of crawling cells
T2 - insights from Dictyostelium
AU - Condeelis, John
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 1993/11
Y1 - 1993/11
N2 - All animal cells are believed to use the same basic molecular mechanisms for locomotion when crawling on a surface. Study of a wide range of crawling cells has tended to confirm this belief but has also led to a diversity of hypotheses for locomotion and a bewildering list of candidate effector proteins. The emergence of a powerful model system, Dictyostelium discoideum, for the study of crawling of cells makes definitive tests of hypotheses for locomotion a reality.
AB - All animal cells are believed to use the same basic molecular mechanisms for locomotion when crawling on a surface. Study of a wide range of crawling cells has tended to confirm this belief but has also led to a diversity of hypotheses for locomotion and a bewildering list of candidate effector proteins. The emergence of a powerful model system, Dictyostelium discoideum, for the study of crawling of cells makes definitive tests of hypotheses for locomotion a reality.
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U2 - 10.1016/0962-8924(93)90085-F
DO - 10.1016/0962-8924(93)90085-F
M3 - Article
C2 - 14731653
AN - SCOPUS:0027482361
VL - 3
SP - 371
EP - 376
JO - Trends in Cell Biology
JF - Trends in Cell Biology
SN - 0962-8924
IS - 11
ER -