Uncompacted myelin lamellae in dysglobulinemic neuropathy

Akio Ohnishi, Asao Hirano

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


Uncompacted lamellae, located preferentially in inner layers of myelin sheath, were observed in biopsied sural nerves of 3 cases of dysglobulinemic neuropathy, in which the main pathological findings of myelinated fibers were those of segmental demyelination and remyelination, and axonal degeneration with concurrent marked decrease of myelinated fiber density. The presence of uncompacted myelin lamellae is well explained by the irregular distribution of adaxonal, incisural and paranodal cytoplasm of the Schwann cell.

Original languageEnglish (US)
Pages (from-to)131-140
Number of pages10
JournalJournal of the Neurological Sciences
Issue number1
StatePublished - Jul 1981

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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