Ultrastructure of cerebral vessels in chick embryo in lead intoxication

Subimal Roy, Asao Hirano, Joseph A. Kochen, Harry M. Zimmerman

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


The ultrastructure of cerebral vessels was studied at various stages of brain development in chick embryos exposed to lead intoxication when they were 4 days old. The endothelial cells showed swelling of mitochondria, presence of many cytolysosomal structures, many tubular bodies, and coated vesicles. A few vessels showed attenuation on the lining endothelial cells. The significance of these morphological alterations are discussed.

Original languageEnglish (US)
Pages (from-to)287-294
Number of pages8
JournalActa neuropathologica
Issue number4
StatePublished - Dec 1 1974


  • Brain
  • Cerebral Endothelium
  • Lead Toxicity
  • Ultrastructure

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience


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