The ultrastructure of cerebral vessels was studied at various stages of brain development in chick embryos exposed to lead intoxication when they were 4 days old. The endothelial cells showed swelling of mitochondria, presence of many cytolysosomal structures, many tubular bodies, and coated vesicles. A few vessels showed attenuation on the lining endothelial cells. The significance of these morphological alterations are discussed.
- Cerebral Endothelium
- Lead Toxicity
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Clinical Neurology
- Cellular and Molecular Neuroscience