Hypothesis: Ultrasound-guided injection of thrombin is the treatment of choice for femoral pseudoaneurysms. Design: A prospective study of patients undergoing a single form of treatment for femoral pseudoaneurysms. Setting: Patients were treated at 2 tertiary care, university-affiliated hospitals. Patients: Forty consecutive patients with femoral pseudoaneurysms resulting from diagnostic and therapeutic catheterizations for peripheral arterial, coronary arterial, and cerebrovascular diseases were evaluated. Intervention: Thrombin was injected directly into the pseudoaneurysms under ultrasonographic guidance. Main Outcome Measure: Thrombosis of the pseudoaneurysm following thrombin injection was the goal of treatment. Results: All 40 patients had initial complete thrombosis of their femoral pseudoaneurysms. In each case, except for one, the aneurysm was noted to have thrombosed on follow-up duplex ultrasongram. There was one complication. Conclusion: Ultrasound-guided thrombin injection is the treatment of choice for femoral pseudoaneurysms.
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