Ubiquitinated eosinophilic granules in the inferior olivary nucleus

S. KATO; A. HIRANO; T. SUENAGA; S. H. YEN

doi:10.1111/j.1365-2990.1990.tb00942.x

Ubiquitinated eosinophilic granules in the inferior olivary nucleus

S. KATO, A. HIRANO, T. SUENAGA, S. H. YEN

Pathology

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Ubiquitinated ìntracytoplasmic eosinophilic granules were found in the inferior olivary neurons of 99 normal individuals. The granules, ranging from 1 to 8 μM in diameter, were round and appeared in groups. Their number increased significantly with ageing. The frequency of the granules in 12 patients with Alzheimer's disease or spinocerebellar degeneration did not differ from that in normal subjects. The ubiquitinated eosinophilic granules can be considered to represent age‐related changes in the inferior olivary neurons.

Original language	English (US)
Pages (from-to)	135-139
Number of pages	5
Journal	Neuropathology and Applied Neurobiology
Volume	16
Issue number	2
DOIs	https://doi.org/10.1111/j.1365-2990.1990.tb00942.x
State	Published - Apr 1990

Keywords

Alzheimer's Disease
ageing
eosinophilic granules
inferior oljve
phosphorylated neuro‐filament
spinocerebellar degeneration
tau protein
ubiquitin

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology
Neurology
Clinical Neurology
Physiology (medical)

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10.1111/j.1365-2990.1990.tb00942.x

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abstract = "Ubiquitinated {\`i}ntracytoplasmic eosinophilic granules were found in the inferior olivary neurons of 99 normal individuals. The granules, ranging from 1 to 8 μM in diameter, were round and appeared in groups. Their number increased significantly with ageing. The frequency of the granules in 12 patients with Alzheimer's disease or spinocerebellar degeneration did not differ from that in normal subjects. The ubiquitinated eosinophilic granules can be considered to represent age‐related changes in the inferior olivary neurons.",

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AU - HIRANO, A.

AU - SUENAGA, T.

AU - YEN, S. H.

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AB - Ubiquitinated ìntracytoplasmic eosinophilic granules were found in the inferior olivary neurons of 99 normal individuals. The granules, ranging from 1 to 8 μM in diameter, were round and appeared in groups. Their number increased significantly with ageing. The frequency of the granules in 12 patients with Alzheimer's disease or spinocerebellar degeneration did not differ from that in normal subjects. The ubiquitinated eosinophilic granules can be considered to represent age‐related changes in the inferior olivary neurons.

KW - Alzheimer's Disease

KW - ageing

KW - eosinophilic granules

KW - inferior oljve

KW - phosphorylated neuro‐filament

KW - spinocerebellar degeneration

KW - tau protein

KW - ubiquitin

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Ubiquitinated eosinophilic granules in the inferior olivary nucleus

Abstract

Keywords

ASJC Scopus subject areas

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