Abstract
The RNP and Sm antigens recognized by lupus erythematosus antibodies are located on discrete particles containing single small nuclear RNA's complexed with proteins. The antigens Ro and La are also on ribonucleoproteins. The small RNA's in ribonucleoproteins with Ro are discrete, like those associated with RNP and Sm; in contrast, ribonucleoproteins with La contain a striking highly banded spectrum of small RNA's from uninfected cells as well as virus-associated RNA from adenovirus-infected cells.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 400-402 |
| Number of pages | 3 |
| Journal | Science |
| Volume | 211 |
| Issue number | 4480 |
| State | Published - 1981 |
| Externally published | Yes |
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ASJC Scopus subject areas
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Cite this
Two novel classes of small ribonucleoproteins detected by antibodies associated with lupus erythematosus. / Lerner, Michael R.; Boyle, John A.; Hardin, John A.; Steitz, Joan A.
In: Science, Vol. 211, No. 4480, 1981, p. 400-402.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Two novel classes of small ribonucleoproteins detected by antibodies associated with lupus erythematosus
AU - Lerner, Michael R.
AU - Boyle, John A.
AU - Hardin, John A.
AU - Steitz, Joan A.
PY - 1981
Y1 - 1981
N2 - The RNP and Sm antigens recognized by lupus erythematosus antibodies are located on discrete particles containing single small nuclear RNA's complexed with proteins. The antigens Ro and La are also on ribonucleoproteins. The small RNA's in ribonucleoproteins with Ro are discrete, like those associated with RNP and Sm; in contrast, ribonucleoproteins with La contain a striking highly banded spectrum of small RNA's from uninfected cells as well as virus-associated RNA from adenovirus-infected cells.
AB - The RNP and Sm antigens recognized by lupus erythematosus antibodies are located on discrete particles containing single small nuclear RNA's complexed with proteins. The antigens Ro and La are also on ribonucleoproteins. The small RNA's in ribonucleoproteins with Ro are discrete, like those associated with RNP and Sm; in contrast, ribonucleoproteins with La contain a striking highly banded spectrum of small RNA's from uninfected cells as well as virus-associated RNA from adenovirus-infected cells.
UR - http://www.scopus.com/inward/record.url?scp=0019459464&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019459464&partnerID=8YFLogxK
M3 - Article
VL - 211
SP - 400
EP - 402
JO - Science
JF - Science
SN - 0036-8075
IS - 4480
ER -