Tricyclic therapy of the DSM-III anxiety disorders: A review with implications for further research

Michael R. Liebowitz, Abby J. Fyer, Jack M. Gorman, Raphael B. Campeas, Diana P. Sandberg, Eric Hollander, Lazlo A. Papp, Donald F. Klein

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

Existing data suggests dramatic efficacy for all tested tricyclics in disorders involving spontaneous panic attacks; moderate efficacy for clomipramine but not other tricyclics in obsessive-compulsive patients; possible, but as yet not well established, tricyclic efficacy in generalized anxiety; and lack of efficacy in simple phobias. Further studies in all DSM-III Anxiety Disorders are both warranted and required to answer the nonological, pathophysiological and treatment questions raised by these findings.

Original languageEnglish (US)
Pages (from-to)7-31
Number of pages25
JournalJournal of Psychiatric Research
Volume22
Issue numberSUPPL. 1
DOIs
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Fingerprint Dive into the research topics of 'Tricyclic therapy of the DSM-III anxiety disorders: A review with implications for further research'. Together they form a unique fingerprint.

  • Cite this

    Liebowitz, M. R., Fyer, A. J., Gorman, J. M., Campeas, R. B., Sandberg, D. P., Hollander, E., Papp, L. A., & Klein, D. F. (1988). Tricyclic therapy of the DSM-III anxiety disorders: A review with implications for further research. Journal of Psychiatric Research, 22(SUPPL. 1), 7-31. https://doi.org/10.1016/0022-3956(88)90067-2