TY - JOUR
T1 - Treatment outcome in depressed latinos predicted by concomitant psychosislike symptoms
AU - Cassano, Paolo
AU - Trinh, Nhi Ha
AU - Chang, Trina
AU - Cusin, Cristina
AU - Fisher, Lauren
AU - Pedrelli, Paola
AU - Nyer, Maren
AU - Kim, Daniel Ju Hyung
AU - Alpert, Jonathan
AU - Mischoulon, David
N1 - Publisher Copyright:
© 2015 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2015
Y1 - 2015
N2 - We compared treatment response (≥50 decrease in Nine-ItemPatient Health Questionnaire total score) among 24 Latinos with major depressive disorder, presenting with and without specific psychosislike symptoms: A, hearing noises or house sounds, B, hearing voices calling one's name, C, seeing fleeting visions such as shadows, and D, symptoms more likely to be truly psychotic (e.g., poorly defined and short-lasting voices [other than B], fleeting paranoid ideation, or fleeting ideas of reference). 18 subjects (75%) endorsed symptoms of cluster A, 12 (50%) of cluster B, 10 (31%) of cluster C, and 12 (50%) of cluster D. Only subjects who reported symptoms from the D cluster exhibited significantly unfavorable depressive outcomes (compared to those with absence of D symptoms). The authors propose a phenomenological differentiation between benign psychosislike symptoms (clusters A-C) and the expression of the psychotic continuum (cluster D) in depressed Latinos.
AB - We compared treatment response (≥50 decrease in Nine-ItemPatient Health Questionnaire total score) among 24 Latinos with major depressive disorder, presenting with and without specific psychosislike symptoms: A, hearing noises or house sounds, B, hearing voices calling one's name, C, seeing fleeting visions such as shadows, and D, symptoms more likely to be truly psychotic (e.g., poorly defined and short-lasting voices [other than B], fleeting paranoid ideation, or fleeting ideas of reference). 18 subjects (75%) endorsed symptoms of cluster A, 12 (50%) of cluster B, 10 (31%) of cluster C, and 12 (50%) of cluster D. Only subjects who reported symptoms from the D cluster exhibited significantly unfavorable depressive outcomes (compared to those with absence of D symptoms). The authors propose a phenomenological differentiation between benign psychosislike symptoms (clusters A-C) and the expression of the psychotic continuum (cluster D) in depressed Latinos.
KW - Antipsychotic augmentation
KW - Latinos
KW - Major depressive disorder
KW - Psychosislike symptoms
KW - Psychotic spectrum
KW - Subthreshold psychosis
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U2 - 10.1097/NMD.0000000000000365
DO - 10.1097/NMD.0000000000000365
M3 - Article
C2 - 26356091
AN - SCOPUS:84943428637
SN - 0022-3018
VL - 203
SP - 769
EP - 773
JO - Journal of Nervous and Mental Disease
JF - Journal of Nervous and Mental Disease
IS - 10
ER -
