Treatment of the Occult Tethered Spinal Cord for Neuropathic Bladder

Results of Sectioning the Filum Terminale

P. D. Metcalfe, T. G. Luerssen, S. J. King, M. Kaefer, K. K. Meldrum, M. P. Cain, R. C. Rink, Anthony J. Casale

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Purpose: Occult tethered cord syndrome applies to patients with signs and symptoms consistent with a caudal spinal cord malformation despite normal neuroimaging. Although several reports of successful surgical treatment exist, controversy remains with respect to patient selection and efficacy. We present a large series with excellent clinical followup, neuroimaging and urodynamic characterization. Materials and Methods: We present our experience with 36 patients at a single institution with preoperative clinical findings, neuroimaging and urodynamics available. Postoperative outcomes were assessed clinically and with urodynamics. We determined predictive parameters to improve patient selection. Results: Approximately 0.04% of pediatric urology clinic visits resulted in neurosurgical referral for the potential of an occult tethered cord. They occurred after failure of a mean of 2 years of aggressive medical management. Daytime urinary incontinence was present in 83% of patients and 47% had encopresis. Preoperative urodynamics were markedly abnormal in all patients with mean bladder capacity 55% of expected capacity. Clinical improvement in urinary symptoms was seen in 72% of patients with resolution of incontinence in 42%. Bowel symptoms improved in 88% of cases, including resolution of encopresis in 53% within 3 months of surgery. Urodynamic improvements were demonstrated in 57% of cases. We were unable to determine preoperative factors that were more likely associated with surgical success. Conclusions: In a highly select population with severe urinary and fecal dysfunction sectioning a normal-appearing filum terminale can result in significant improvement. We were unable to identify factors that may increase the chance of surgical success.

Original languageEnglish (US)
Pages (from-to)1826-1830
Number of pages5
JournalJournal of Urology
Volume176
Issue number4 SUPPL.
DOIs
StatePublished - Oct 2006
Externally publishedYes

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Cauda Equina
Neurogenic Urinary Bladder
Urodynamics
Spinal Cord
Encopresis
Neuroimaging
Patient Selection
Diurnal Enuresis
Therapeutics
Neural Tube Defects
Urology
Ambulatory Care
Signs and Symptoms
Urinary Bladder
Referral and Consultation
Pediatrics
Population

Keywords

  • bladder
  • neural tube defects
  • neurogenic
  • urodynamics

ASJC Scopus subject areas

  • Urology

Cite this

Treatment of the Occult Tethered Spinal Cord for Neuropathic Bladder : Results of Sectioning the Filum Terminale. / Metcalfe, P. D.; Luerssen, T. G.; King, S. J.; Kaefer, M.; Meldrum, K. K.; Cain, M. P.; Rink, R. C.; Casale, Anthony J.

In: Journal of Urology, Vol. 176, No. 4 SUPPL., 10.2006, p. 1826-1830.

Research output: Contribution to journalArticle

Metcalfe, PD, Luerssen, TG, King, SJ, Kaefer, M, Meldrum, KK, Cain, MP, Rink, RC & Casale, AJ 2006, 'Treatment of the Occult Tethered Spinal Cord for Neuropathic Bladder: Results of Sectioning the Filum Terminale', Journal of Urology, vol. 176, no. 4 SUPPL., pp. 1826-1830. https://doi.org/10.1016/j.juro.2006.04.090
Metcalfe, P. D. ; Luerssen, T. G. ; King, S. J. ; Kaefer, M. ; Meldrum, K. K. ; Cain, M. P. ; Rink, R. C. ; Casale, Anthony J. / Treatment of the Occult Tethered Spinal Cord for Neuropathic Bladder : Results of Sectioning the Filum Terminale. In: Journal of Urology. 2006 ; Vol. 176, No. 4 SUPPL. pp. 1826-1830.
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