Treatment of mononeuropathy multiplex in hepatitis C virus and cryoglobulinemia

S. N. Scelsa, Steven Herskovitz, B. Reichler

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Recent reports advocate α-interferon (α-Ifn) treatment for mononeuropathy multiplex in hepatitis C virus-associated cryoglobulinemia. We report 2 patients with this disorder to describe two underrecognized treatment outcomes - worsening of polyneuropathy with initiation of α-Ifn, in the absence of immunosuppression, and deterioration of liver function with prednisone, despite improvement of polyneuropathy.

Original languageEnglish (US)
Pages (from-to)1526-1529
Number of pages4
JournalMuscle and Nerve
Volume21
Issue number11
DOIs
StatePublished - 1998
Externally publishedYes

Fingerprint

Mononeuropathies
Cryoglobulinemia
Polyneuropathies
Hepacivirus
Prednisone
Immunosuppression
Interferons
Liver
Therapeutics

Keywords

  • Alpha-interferon
  • Cryoglobulinemia
  • Hepatitis C virus
  • Mononeuropathy multiplex
  • Polyneuropathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Treatment of mononeuropathy multiplex in hepatitis C virus and cryoglobulinemia. / Scelsa, S. N.; Herskovitz, Steven; Reichler, B.

In: Muscle and Nerve, Vol. 21, No. 11, 1998, p. 1526-1529.

Research output: Contribution to journalArticle

@article{96134ddff4414954966ce84e404c9e13,
title = "Treatment of mononeuropathy multiplex in hepatitis C virus and cryoglobulinemia",
abstract = "Recent reports advocate α-interferon (α-Ifn) treatment for mononeuropathy multiplex in hepatitis C virus-associated cryoglobulinemia. We report 2 patients with this disorder to describe two underrecognized treatment outcomes - worsening of polyneuropathy with initiation of α-Ifn, in the absence of immunosuppression, and deterioration of liver function with prednisone, despite improvement of polyneuropathy.",
keywords = "Alpha-interferon, Cryoglobulinemia, Hepatitis C virus, Mononeuropathy multiplex, Polyneuropathy",
author = "Scelsa, {S. N.} and Steven Herskovitz and B. Reichler",
year = "1998",
doi = "10.1002/(SICI)1097-4598(199811)21:11<1526::AID-MUS23>3.0.CO;2-X",
language = "English (US)",
volume = "21",
pages = "1526--1529",
journal = "Muscle and Nerve",
issn = "0148-639X",
publisher = "John Wiley and Sons Inc.",
number = "11",

}

TY - JOUR

T1 - Treatment of mononeuropathy multiplex in hepatitis C virus and cryoglobulinemia

AU - Scelsa, S. N.

AU - Herskovitz, Steven

AU - Reichler, B.

PY - 1998

Y1 - 1998

N2 - Recent reports advocate α-interferon (α-Ifn) treatment for mononeuropathy multiplex in hepatitis C virus-associated cryoglobulinemia. We report 2 patients with this disorder to describe two underrecognized treatment outcomes - worsening of polyneuropathy with initiation of α-Ifn, in the absence of immunosuppression, and deterioration of liver function with prednisone, despite improvement of polyneuropathy.

AB - Recent reports advocate α-interferon (α-Ifn) treatment for mononeuropathy multiplex in hepatitis C virus-associated cryoglobulinemia. We report 2 patients with this disorder to describe two underrecognized treatment outcomes - worsening of polyneuropathy with initiation of α-Ifn, in the absence of immunosuppression, and deterioration of liver function with prednisone, despite improvement of polyneuropathy.

KW - Alpha-interferon

KW - Cryoglobulinemia

KW - Hepatitis C virus

KW - Mononeuropathy multiplex

KW - Polyneuropathy

UR - http://www.scopus.com/inward/record.url?scp=0031711085&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031711085&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1097-4598(199811)21:11<1526::AID-MUS23>3.0.CO;2-X

DO - 10.1002/(SICI)1097-4598(199811)21:11<1526::AID-MUS23>3.0.CO;2-X

M3 - Article

C2 - 9771679

AN - SCOPUS:0031711085

VL - 21

SP - 1526

EP - 1529

JO - Muscle and Nerve

JF - Muscle and Nerve

SN - 0148-639X

IS - 11

ER -